Details for: Rgl2

Gene ID: 19732

Symbol: Rgl2

Ensembl ID: ENSMUSG00000041354

Description: ral guanine nucleotide dissociation stimulator-like 2

Associated with

  • Mapk1/mapk3 signaling
    (R-MMU-5684996)
  • Mapk family signaling cascades
    (R-MMU-5683057)
  • Raf/map kinase cascade
    (R-MMU-5673001)
  • Guanyl-nucleotide exchange factor activity
    (GO:0005085)
  • Negative regulation of cardiac muscle cell apoptotic process
    (GO:0010667)
  • Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
    (GO:0051897)
  • Regulation of ral protein signal transduction
    (GO:0032485)
  • Signal transduction
    (GO:0007165)
  • Small gtpase-mediated signal transduction
    (GO:0007264)

Other Information

Genular Protein ID: 2414955800

Symbol: RGL2_MOUSE

Name: Ral guanine nucleotide dissociation stimulator-like 2

UniProtKB Accession Codes:

Q61193 Q9QUJ2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 5 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 4 PIR 1 PRO 1 PROSITE 4 PROSITE-ProRule 3 PaxDb 1 PeptideAtlas 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 8710374

Title: RalGDS-like factor (Rlf) is a novel Ras and Rap 1A-associating protein.

PubMed ID: 8710374

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 9753431

Title: Structure determination of the Ras-binding domain of the Ral-specific guanine nucleotide exchange factor Rlf.

PubMed ID: 9753431

DOI: 10.1021/bi9811664

Sequence Information:

  • Length: 778
  • Mass: 83826
  • Checksum: B23CB882A5416564
  • Sequence:
    • MLPRPLRLLL DTTPPGGVVL SSFRSRDPEE GGDPGGRAVG GGQEEEDEEE EEASVSVWDE 
EEDGATFTVT SRQYRPLDPL APLPPPRSSR RLRAGTLEAL VRHLLDARTA GADMMFTPAL 
LATHRAFTST PALFGLVADR LEALESHPPG ELERTTGVAI SVLSTWLASH PEDFGSEVKG 
QLDRLESFLL RTGYAAREGV VGGSADLIRN LRARVDPRAP DLPKPLALPG DSPADPTDVL 
VFLADHLAEQ LTLLDAELFL NLIPSQCLGG LWGHRDRPGH SHLCPSVRAT VTQFNKVAGA 
VVSSVLGATS IGEGPREVTV RPLRPPQRAR LLEKWIRVAE ECRLLRNFSS VYAVVSALQS 
SPIHRLRAAW GETTRDSLRV FSSLCQIFSE EDNYSQSREL LMQEVKPQPP VEPHSKKAPR 
SGFRGGGVVP YLGTFLKDLV MLDAASKDEL ENGYINFDKR RKEFAILSEL LRLQKECRGY 
DLRPNSDIQQ WLQGLQPLTE AQSHRVSCEV EPPGTSDSPA ARTPRPTLVI TQWTEVLGSV 
GGPTPLVSWD RPSVGGDEVP GTPAPLLTRL AQHMKWPSVS SLDSALESSP SLHSPADPGH 
LSPPASSPRP SRGHRRSASC GSPLSGNTGE GTSRSAGCGG GVSGPGSSDC RIIRVQMELG 
EDGSVYKSIL VTSQDKAPSV ISRVLKKNNR DSAVASEFEL VQLLPGDREL TIPHSANVFY 
AMDGASHDFL LRQRRRPSAA TPGSHSGPSA SGTPPSEGGG GSFPRIKATG RKIARALF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.