Genular: Defining Cellular Identity and Function

Details for: Rgs16

Gene ID: 19734

Symbol: Rgs16

Ensembl ID: ENSMUSG00000026475

Description: regulator of G-protein signaling 16

Associated with

G alpha (i) signalling events
(R-MMU-418594)
G alpha (q) signalling events
(R-MMU-416476)
G alpha (z) signalling events
(R-MMU-418597)
Gpcr downstream signalling
(R-MMU-388396)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Cytoplasm
(GO:0005737)
G protein-coupled receptor signaling pathway
(GO:0007186)
Gtpase activator activity
(GO:0005096)
Membrane
(GO:0016020)
Negative regulation of signal transduction
(GO:0009968)
Positive regulation of gtpase activity
(GO:0043547)
Protein binding
(GO:0005515)

Other Information

Proteins

Regulator of G-protein signaling 16

Genular Protein ID: 563581712

Symbol: RGS16_MOUSE

Name: Regulator of G-protein signaling 16

UniProtKB Accession Codes:

P97428 O09091 P97420 Q80V16

Database IDs:

Citations:

PubMed ID: 8917514

Title: RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling.

PubMed ID: 8917514

DOI: 10.1073/pnas.93.23.12885

PubMed ID: 9079700

Title: Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast.

PubMed ID: 9079700

DOI: 10.1074/jbc.272.13.8679

PubMed ID: 9223279

Title: The p53 tumor suppressor targets a novel regulator of G protein signaling.

PubMed ID: 9223279

DOI: 10.1073/pnas.94.15.7868

PubMed ID: 9469939

Title: Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene.

PubMed ID: 9469939

DOI: 10.1016/s0378-1119(97)00593-3

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10373502

Title: Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling.

PubMed ID: 10373502

DOI: 10.1074/jbc.274.26.18836

PubMed ID: 18434540

Title: Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation.

PubMed ID: 18434540

DOI: 10.1073/pnas.0801569105

Sequence Information:

Length: 201
Mass: 22691
Checksum: AE3D798F15787392
Sequence:

MCRTLATFPN TCLERAKEFK TRLGIFLHKS ELSSDTGGIS KFEWASKHNK ERSFSEDVLG 
WRESFDLLLN SKNGVAAFHA FLKTEFSEEN LEFWLACEEF KKIRSATKLA SRAHHIFDEY 
IRSEAPKEVN IDHETRELTK TNLQAATTSC FDVAQGKTRT LMEKDSYPRF LKSPAYRDLA 
AQASATSTSA PSGSPAEPSH T

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rgs16

Associated with

Other Information

RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling. PubMed ID: 8917514

Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast. PubMed ID: 9079700

The p53 tumor suppressor targets a novel regulator of G protein signaling. PubMed ID: 9223279

Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene. PubMed ID: 9469939

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling. PubMed ID: 10373502

Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation. PubMed ID: 18434540