Genular: Defining Cellular Identity and Function

Details for: Rgs2

Gene ID: 19735

Symbol: Rgs2

Ensembl ID: ENSMUSG00000026360

Description: regulator of G-protein signaling 2

Associated with

G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Adenylate cyclase inhibitor activity
(GO:0010855)
Beta-tubulin binding
(GO:0048487)
Brown fat cell differentiation
(GO:0050873)
Cell cycle
(GO:0007049)
Cytoplasm
(GO:0005737)
Cytoplasmic side of plasma membrane
(GO:0009898)
Cytosol
(GO:0005829)
G-protein alpha-subunit binding
(GO:0001965)
G protein-coupled receptor signaling pathway
(GO:0007186)
Gtpase activator activity
(GO:0005096)
Membrane
(GO:0016020)
Negative regulation of cardiac muscle hypertrophy
(GO:0010614)
Negative regulation of cell growth involved in cardiac muscle cell development
(GO:0061052)
Negative regulation of glycine import across plasma membrane
(GO:1900924)
Negative regulation of g protein-coupled receptor signaling pathway
(GO:0045744)
Negative regulation of map kinase activity
(GO:0043407)
Negative regulation of phospholipase activity
(GO:0010519)
Negative regulation of signal transduction
(GO:0009968)
Negative regulation of translation
(GO:0017148)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of cardiac muscle contraction
(GO:0060452)
Positive regulation of neuron projection development
(GO:0010976)
Protein binding
(GO:0005515)
Regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway
(GO:0071877)
Regulation of g protein-coupled receptor signaling pathway
(GO:0008277)
Regulation of translation
(GO:0006417)
Relaxation of cardiac muscle
(GO:0055119)
Relaxation of vascular associated smooth muscle
(GO:0060087)
Spermatogenesis
(GO:0007283)

Other Information

Proteins

Regulator of G-protein signaling 2

Genular Protein ID: 3244454030

Symbol: RGS2_MOUSE

Name: Regulator of G-protein signaling 2

UniProtKB Accession Codes:

O08849 Q544S7 Q91WX1 Q9JL24

Database IDs:

Citations:

PubMed ID: 9079700

Title: Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast.

PubMed ID: 9079700

DOI: 10.1074/jbc.272.13.8679

PubMed ID: 10779778

Title: RGS molecule expression in murine B lymphocytes and ability to down-regulate chemotaxis to lymphoid chemokines.

PubMed ID: 10779778

DOI: 10.4049/jimmunol.164.9.4720

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14608379

Title: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure.

PubMed ID: 14608379

DOI: 10.1038/nm958

Sequence Information:

Length: 211
Mass: 24294
Checksum: 5D6E255C2BC7E7FA
Sequence:

MQSAMFLAVQ HDCVPMDKSA GNGPKVEEKR EKMKRTLLKD WKTRLSYFLQ NSSAPGKPKT 
GKKSKQQTFI KPSPEEAQLW AEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK 
KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKSLIAQ NIQEATSGCF TTAQKRVYSL 
MENNSYPRFL ESEFYQDLCK KPQITTEPHA T

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rgs2

Associated with

Other Information

Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast. PubMed ID: 9079700

RGS molecule expression in murine B lymphocytes and ability to down-regulate chemotaxis to lymphoid chemokines. PubMed ID: 10779778

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072