Genular: Defining Cellular Identity and Function

Details for: Rit2

Gene ID: 19762

Symbol: Rit2

Ensembl ID: ENSMUSG00000057455

Description: Ras-like without CAAX 2

Associated with

Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Calmodulin binding
(GO:0005516)
Cell body
(GO:0044297)
Chromatin binding
(GO:0003682)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dendritic tree
(GO:0097447)
Gdp binding
(GO:0019003)
Golgi apparatus
(GO:0005794)
G protein activity
(GO:0003925)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hydrolase activity
(GO:0016787)
Intracellular signal transduction
(GO:0035556)
Maintenance of protein location in cell
(GO:0032507)
Mapk cascade
(GO:0000165)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Negative regulation of neuron projection development
(GO:0010977)
Neuron projection
(GO:0043005)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Ras protein signal transduction
(GO:0007265)
Regulation of calcium-mediated signaling
(GO:0050848)
Regulation of cdc42 protein signal transduction
(GO:0032489)
Regulation of endocytosis
(GO:0030100)
Regulation of erk1 and erk2 cascade
(GO:0070372)
Regulation of protein phosphorylation
(GO:0001932)
Semaphorin receptor binding
(GO:0030215)
Signal transduction
(GO:0007165)

Other Information

Proteins

GTP-binding protein Rit2

Genular Protein ID: 64268985

Symbol: RIT2_MOUSE

Name: GTP-binding protein Rit2

UniProtKB Accession Codes:

P70425 Q3UST1 Q3UUP4 Q8BQT5 Q9QWX5

Database IDs:

Citations:

PubMed ID: 8824319

Title: Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.

PubMed ID: 8824319

DOI: 10.1523/jneurosci.16-21-06784.1996

PubMed ID: 10545207

Title: Biochemical characterization of the Ras-related GTPases Rit and Rin.

PubMed ID: 10545207

DOI: 10.1006/abbi.1999.1448

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12934100

Title: Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor.

PubMed ID: 12934100

DOI: 10.1038/sj.onc.1206635

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23805044

Title: RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.

PubMed ID: 23805044

Sequence Information:

Length: 217
Mass: 24802
Checksum: 189AA6DCCE75034F
Sequence:

MEVENEAHCC PGSSSGGSRE YKVVMLGAGG VGKSAVTMQF ISHQFPDYHD PTIEDAYKTQ 
VRIDNEPAYL DILDTAGQAE FTAMREQYMR GGEGFIICYS VTDRQSFQEA AKFKELIFQV 
RHTYEIPLVL VGNKIDLEQF RQVSTEEGMN LARDYNCAFF ETSAALRFGI DDAFQGLVRE 
IRRKESMLSL VERKLKRKDS LWKKIKASLK KKRENML

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rit2

Associated with

Other Information

Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins. PubMed ID: 8824319

Biochemical characterization of the Ras-related GTPases Rit and Rin. PubMed ID: 10545207

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Functional interaction between the small GTP-binding protein Rin and the N-terminal of Brn-3a transcription factor. PubMed ID: 12934100

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. PubMed ID: 23805044