Genular: Defining Cellular Identity and Function

Details for: Ring1

Gene ID: 19763

Symbol: Ring1

Ensembl ID: ENSMUSG00000024325

Description: ring finger protein 1

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Rna polymerase ii transcription
(R-MMU-73857)
Runx1 interacts with co-factors whose precise effect on runx1 targets is not known
(R-MMU-8939243)
Sumo e3 ligases sumoylate target proteins
(R-MMU-3108232)
Sumoylation
(R-MMU-2990846)
Sumoylation of chromatin organization proteins
(R-MMU-4551638)
Sumoylation of dna damage response and repair proteins
(R-MMU-3108214)
Sumoylation of rna binding proteins
(R-MMU-4570464)
Sumoylation of transcription cofactors
(R-MMU-3899300)
Transcriptional regulation by e2f6
(R-MMU-8953750)
Transcriptional regulation by runx1
(R-MMU-8878171)
Anterior/posterior pattern specification
(GO:0009952)
Camera-type eye morphogenesis
(GO:0048593)
Chromatin binding
(GO:0003682)
Chromatin organization
(GO:0006325)
Chromatin remodeling
(GO:0006338)
Cytosol
(GO:0005829)
Metal ion binding
(GO:0046872)
Negative regulation of dna-templated transcription
(GO:0045892)
Nuclear body
(GO:0016604)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Pcg protein complex
(GO:0031519)
Prc1 complex
(GO:0035102)
Protein binding
(GO:0005515)
Sex chromatin
(GO:0001739)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activator activity
(GO:0097027)
Ubiquitin ligase complex
(GO:0000151)
Ubiquitin protein ligase activity
(GO:0061630)

Other Information

Proteins

E3 ubiquitin-protein ligase RING1

Genular Protein ID: 4025190021

Symbol: RING1_MOUSE

Name: E3 ubiquitin-protein ligase RING1

UniProtKB Accession Codes:

O35730 Q3U242 Q3U333 Q4FK33 Q63ZX8 Q921Z8

Database IDs:

Citations:

PubMed ID: 9312051

Title: Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.

PubMed ID: 9312051

DOI: 10.1093/emboj/16.19.5930

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15525528

Title: Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.

PubMed ID: 15525528

DOI: 10.1016/j.devcel.2004.10.005

PubMed ID: 16359901

Title: Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.

PubMed ID: 16359901

DOI: 10.1016/j.molcel.2005.12.002

PubMed ID: 16710298

Title: Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

PubMed ID: 16710298

DOI: 10.1038/sj.emboj.7601144

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 406
Mass: 42631
Checksum: 4F274E976974A2D8
Sequence:

MTTPANAQNA SKTWELSLYE LHRTPQEAIM DGTEIAVSPR SLHSELMCPI CLDMLKNTMT 
TKECLHRFCS DCIVTALRSG NKECPTCRKK LVSKRSLRPD PNFDALISKI YPSREEYEAH 
QDRVLIRLSR LHNQQALSSS IEEGLRMQAM HRAQRVRRPM PGSDQTATMS GGEGEPGEGE 
GDGEDVSSDS APDSAPGPAP KRPRGAGAGA SSVGTGGGAA GGACGGAGSE DSGDRGGTLG 
GGTLGPPSPP GAPSPPEPGG EIELVFRPHP LLVEKGEYCQ TRYVKTTGNA TVDHLSKYLA 
LRIALERRQQ QETTEPGGPG GGASDTGGPD GGGGERGVAG GGEGPEEPAL PSLEGVSEKQ 
YTIYIAPGGG AFTTLNGSLT LELVNEKFWK VSRPLELCYA PTKDPK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ring1

Associated with

Other Information

Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain. PubMed ID: 9312051

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. PubMed ID: 15525528

Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. PubMed ID: 16359901

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b. PubMed ID: 16710298

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079