Details for: Ripk1
Associated with
Other Information
Genular Protein ID: 2435568562
Symbol: RIPK1_MOUSE
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7538908
Title: RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.
PubMed ID: 7538908
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12654725
Title: The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation.
PubMed ID: 12654725
DOI: 10.1101/gad.1062403
PubMed ID: 17301840
Title: RIP1, a kinase on the crossroads of a cell's decision to live or die.
PubMed ID: 17301840
PubMed ID: 18442983
Title: Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1.
PubMed ID: 18442983
PubMed ID: 18239685
Title: Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation.
PubMed ID: 18239685
DOI: 10.1038/emboj.2008.5
PubMed ID: 19590578
Title: DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB.
PubMed ID: 19590578
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 23283962
Title: DNA sensing-independent inhibition of herpes simplex virus 1 replication by DAI/ZBP1.
PubMed ID: 23283962
DOI: 10.1128/jvi.02860-12
PubMed ID: 24813849
Title: RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
PubMed ID: 24813849
PubMed ID: 24813850
Title: RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
PubMed ID: 24813850
PubMed ID: 25459879
Title: The two faces of receptor interacting protein kinase-1.
PubMed ID: 25459879
PubMed ID: 24557836
Title: Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.
PubMed ID: 24557836
PubMed ID: 27819681
Title: RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.
PubMed ID: 27819681
DOI: 10.1038/nature20558
PubMed ID: 27819682
Title: RIPK1 inhibits ZBP1-driven necroptosis during development.
PubMed ID: 27819682
DOI: 10.1038/nature20559
PubMed ID: 28842570
Title: Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.
PubMed ID: 28842570
PubMed ID: 28701375
Title: SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.
PubMed ID: 28701375
PubMed ID: 29883609
Title: PELI1 selectively targets kinase-active RIP3 for ubiquitylation-dependent proteasomal degradation.
PubMed ID: 29883609
PubMed ID: 29440439
Title: Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis.
PubMed ID: 29440439
PubMed ID: 30867408
Title: RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development.
PubMed ID: 30867408
PubMed ID: 30185824
Title: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.
PubMed ID: 30185824
PubMed ID: 31457011
PubMed ID: 31358656
Title: ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1.
PubMed ID: 31358656
PubMed ID: 30498077
Title: Viral M45 and necroptosis-associated proteins form heteromeric amyloid assemblies.
PubMed ID: 30498077
PubMed ID: 30988283
Title: Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation.
PubMed ID: 30988283
PubMed ID: 31519887
Title: K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation.
PubMed ID: 31519887
PubMed ID: 31519886
Title: Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.
PubMed ID: 31519886
PubMed ID: 31511692
Title: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
PubMed ID: 31511692
PubMed ID: 31827281
Title: Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.
PubMed ID: 31827281
PubMed ID: 31827280
Title: A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1.
PubMed ID: 31827280
PubMed ID: 34471287
Title: AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
PubMed ID: 34471287
PubMed ID: 33397971
Title: ZBP1 promotes LPS-induced cell death and IL-1beta release via RHIM-mediated interactions with RIPK1.
PubMed ID: 33397971
Sequence Information:
- Length: 656
- Mass: 74854
- Checksum: ABB350B523879933
- Sequence:
MQPDMSLDNI KMASSDLLEK TDLDSGGFGK VSLCYHRSHG FVILKKVYTG PNRAEYNEVL LEEGKMMHRL RHSRVVKLLG IIIEEGNYSL VMEYMEKGNL MHVLKTQIDV PLSLKGRIIV EAIEGMCYLH DKGVIHKDLK PENILVDRDF HIKIADLGVA SFKTWSKLTK EKDNKQKEVS STTKKNNGGT LYYMAPEHLN DINAKPTEKS DVYSFGIVLW AIFAKKEPYE NVICTEQFVI CIKSGNRPNV EEILEYCPRE IISLMERCWQ AIPEDRPTFL GIEEEFRPFY LSHFEEYVEE DVASLKKEYP DQSPVLQRMF SLQHDCVPLP PSRSNSEQPG SLHSSQGLQM GPVEESWFSS SPEYPQDEND RSVQAKLQEE ASYHAFGIFA EKQTKPQPRQ NEAYNREEER KRRVSHDPFA QQRARENIKS AGARGHSDPS TTSRGIAVQQ LSWPATQTVW NNGLYNQHGF GTTGTGVWYP PNLSQMYSTY KTPVPETNIP GSTPTMPYFS GPVADDLIKY TIFNSSGIQI GNHNYMDVGL NSQPPNNTCK EESTSRHQAI FDNTTSLTDE HLNPIRENLG RQWKNCARKL GFTESQIDEI DHDYERDGLK EKVYQMLQKW LMREGTKGAT VGKLAQALHQ CCRIDLLNHL IRASQS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.