Details for: Rnf2

Gene ID: 19821

Symbol: Rnf2

Ensembl ID: ENSMUSG00000026484

Description: ring finger protein 2

Associated with

Other Information

Genular Protein ID: 3451642951

Symbol: RING2_MOUSE

Name: E3 ubiquitin-protein ligase RING2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9312051

Title: Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain.

PubMed ID: 9312051

DOI: 10.1093/emboj/16.19.5930

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10369680

Title: RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1.

PubMed ID: 10369680

DOI: 10.1093/emboj/18.12.3404

PubMed ID: 12183370

Title: Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.

PubMed ID: 12183370

DOI: 10.1242/dev.129.18.4171

PubMed ID: 15525528

Title: Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.

PubMed ID: 15525528

DOI: 10.1016/j.devcel.2004.10.005

PubMed ID: 15509584

Title: Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation.

PubMed ID: 15509584

DOI: 10.1074/jbc.c400493200

PubMed ID: 16024804

Title: Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes.

PubMed ID: 16024804

DOI: 10.1128/mcb.25.15.6694-6706.2005

PubMed ID: 19170609

Title: The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA.

PubMed ID: 19170609

DOI: 10.1021/bi801933c

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22325148

Title: RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3.

PubMed ID: 22325148

DOI: 10.1016/j.cell.2011.12.029

PubMed ID: 22226355

Title: Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells.

PubMed ID: 22226355

DOI: 10.1016/j.stem.2011.12.006

PubMed ID: 22872859

Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.

PubMed ID: 22872859

DOI: 10.1074/mcp.m112.017194

PubMed ID: 24034696

Title: The Aurora B kinase and the Polycomb protein Ring1B combine to regulate active promoters in quiescent lymphocytes.

PubMed ID: 24034696

DOI: 10.1016/j.molcel.2013.08.022

PubMed ID: 24980959

Title: RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy.

PubMed ID: 24980959

DOI: 10.1038/cr.2014.85

PubMed ID: 28596365

Title: PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.

PubMed ID: 28596365

DOI: 10.1126/science.aal2512

PubMed ID: 16710298

Title: Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

PubMed ID: 16710298

DOI: 10.1038/sj.emboj.7601144

Sequence Information:

  • Length: 336
  • Mass: 37623
  • Checksum: 84BA5B3E044DB7EC
  • Sequence:
  • MSQAVQTNGT QPLSKTWELS LYELQRTPQE AITDGLEIVV SPRSLHSELM CPICLDMLKN 
    TMTTKECLHR FCADCIITAL RSGNKECPTC RKKLVSKRSL RPDPNFDALI SKIYPSRDEY 
    EAHQERVLAR INKHNNQQAL SHSIEEGLKI QAMNRLQRGK KQQIENGSGA EDNGDSSHCS 
    NASTHSNQEA GPSNKRTKTS DDSGLELDNN NAAVAIDPVM DGASEIELVF RPHPTLMEKD 
    DSAQTRYIKT SGNATVDHLS KYLAVRLALE ELRSKGESNQ MNLDTASEKQ YTIYIATASG 
    QFTVLNGSFS LELVSEKYWK VNKPMELYYA PTKEHK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.