Genular: Defining Cellular Identity and Function

Details for: Rnf4

Gene ID: 19822

Symbol: Rnf4

Ensembl ID: ENSMUSG00000029110

Description: ring finger protein 4

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Dna double-strand break repair
(R-MMU-5693532)
Dna repair
(R-MMU-73894)
Hdr through homologous recombination (hrr) or single strand annealing (ssa)
(R-MMU-5693567)
Homology directed repair
(R-MMU-5693538)
Immune system
(R-MMU-168256)
Processing of dna double-strand break ends
(R-MMU-5693607)
Cellular response to gamma radiation
(GO:0071480)
Cellular response to hydroxyurea
(GO:0072711)
Cellular response to testosterone stimulus
(GO:0071394)
Cytoplasm
(GO:0005737)
Dna binding
(GO:0003677)
Identical protein binding
(GO:0042802)
Metal ion binding
(GO:0046872)
Microtubule end
(GO:1990752)
Negative regulation of protein localization to chromatin
(GO:0120186)
Nuclear androgen receptor binding
(GO:0050681)
Nuclear body
(GO:0016604)
Nuclear estrogen receptor binding
(GO:0030331)
Nucleoplasm
(GO:0005654)
Nucleosome binding
(GO:0031491)
Nucleus
(GO:0005634)
Pml body
(GO:0016605)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein autoubiquitination
(GO:0051865)
Protein binding
(GO:0005515)
Protein k6-linked ubiquitination
(GO:0085020)
Protein k11-linked ubiquitination
(GO:0070979)
Protein k48-linked ubiquitination
(GO:0070936)
Protein k63-linked ubiquitination
(GO:0070534)
Protein ubiquitination
(GO:0016567)
Regulation of kinetochore assembly
(GO:0090234)
Regulation of spindle assembly
(GO:0090169)
Response to arsenic-containing substance
(GO:0046685)
Sumo polymer binding
(GO:0032184)
Tbp-class protein binding
(GO:0017025)
Transcription factor binding
(GO:0008134)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin conjugating enzyme binding
(GO:0031624)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

RNF4_MOUSE

Genular Protein ID: 1323673080

Symbol: RNF4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9QZS2 O35941 Q541Z6

Database IDs:

Citations:

PubMed ID: 10822263

Title: Rnf4, a RING protein expressed in the developing nervous and reproductive systems, interacts with Gscl, a gene within the DiGeorge critical region.

PubMed ID: 10822263

DOI: 10.1002/(sici)1097-0177(200005)218:1<102::aid-dvdy9>3.0.co;2-a

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9479498

Title: Identification and characterization of a novel RING-finger gene (RNF4) mapping at 4p16.3.

PubMed ID: 9479498

DOI: 10.1006/geno.1997.5105

PubMed ID: 10849425

Title: Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingers.

PubMed ID: 10849425

DOI: 10.1074/jbc.m003405200

PubMed ID: 12885770

Title: The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor.

PubMed ID: 12885770

DOI: 10.1074/jbc.m306259200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19779455

Title: PARP-1 transcriptional activity is regulated by sumoylation upon heat shock.

PubMed ID: 19779455

DOI: 10.1038/emboj.2009.279

PubMed ID: 20681948

Title: RING domain dimerization is essential for RNF4 function.

PubMed ID: 20681948

DOI: 10.1042/bj20100957

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 194
Mass: 21911
Checksum: 9A0A4277725C62E5
Sequence:

MSTRNPQRKR RGGTVNSRQT QKRTRETTST PEVSLETEPI ELVETVGDEI VDLTCESLEP 
VVVDLTHNDS VVIVEERRRP RRNGRRLRQD HADSCVVSSD DEELSRDKDV YVTTHTPRST 
KDDGATGPRP SGTVSCPICM DGYSEIVQNG RLIVSTECGH VFCSQCLRDS LKNANTCPTC 
RKKINHKRYH PIYI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rnf4

Associated with

Other Information

Rnf4, a RING protein expressed in the developing nervous and reproductive systems, interacts with Gscl, a gene within the DiGeorge critical region. PubMed ID: 10822263

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification and characterization of a novel RING-finger gene (RNF4) mapping at 4p16.3. PubMed ID: 9479498

Interaction between the transcription factor SPBP and the positive cofactor RNF4. An interplay between protein binding zinc fingers. PubMed ID: 10849425

The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor. PubMed ID: 12885770

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

PARP-1 transcriptional activity is regulated by sumoylation upon heat shock. PubMed ID: 19779455

RING domain dimerization is essential for RNF4 function. PubMed ID: 20681948

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079