Details for: Slc22a8

Gene ID: 19879

Symbol: Slc22a8

Ensembl ID: ENSMUSG00000063796

Description: solute carrier family 22 (organic anion transporter), member 8

Associated with

Other Information

Genular Protein ID: 483195500

Symbol: S22A8_MOUSE

Name: Organic anion/dicarboxylate exchanger

UniProtKB Accession Codes:

O88909 Q3TZF9 Q8CCX3 Q8CFH5 Q91WJ9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 46 ChEMBL 1 DNASU 1 EMBL 6 Ensembl 2 GO 14 Gene3D 1 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 4 Rhea 23 SAM 1 SMR 1 STRING 1 SUPFAM 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 10087192

Title: A novel putative transporter maps to the osteosclerosis (oc) mutation and is not expressed in the oc mutant mouse.

PubMed ID: 10087192

DOI: 10.1006/geno.1998.5722

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12011098

Title: Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

PubMed ID: 12011098

DOI: 10.1074/jbc.m203803200

PubMed ID: 15075193

Title: Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice.

PubMed ID: 15075193

DOI: 10.1152/ajprenal.00356.2003

PubMed ID: 15100168

Title: Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.

PubMed ID: 15100168

DOI: 10.1124/dmd.32.5.479

PubMed ID: 15944205

Title: Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites.

PubMed ID: 15944205

DOI: 10.1152/ajpcell.00619.2004

PubMed ID: 17220594

Title: Role of mouse organic anion transporter 3 (mOat3) as a basolateral prostaglandin E2 transport pathway.

PubMed ID: 17220594

DOI: 10.1254/jphs.fp0060816

PubMed ID: 21325432

Title: Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice.

PubMed ID: 21325432

DOI: 10.1124/dmd.110.036863

PubMed ID: 23389457

Title: Sex-dependent expression of Oat3 (Slc22a8) and Oat1 (Slc22a6) proteins in murine kidneys.

PubMed ID: 23389457

DOI: 10.1152/ajprenal.00201.2012

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 537
  • Mass: 59246
  • Checksum: F85FF82002AB26EB
  • Sequence:
    • MTFSEILDRV GSMGPFQYLH VTLLALPILG IANHNLLQIF TATTPDHHCR PPPNASLEPW 
VLPLGPNGKP EKCLRFVHLP NASLPNDTQG ATEPCLDGWI YNSTRDTIVT EWDLVCGSNK 
LKEMAQSVFM AGILVGGPVF GELSDRFGRK PILTWSYLLL AASGSSAAFS PSLTVYMIFR 
FLCGCSISGI SLSTIILNVE WVPTSTRAIS STTIGYCYTI GQFILPGLAY AVPQWRWLQL 
SVSAAFFIFS LLSWWVPESI RWLVLSGKFS KALKTLQRVA TFNGKKEEGE KLTVEELKFN 
LQKDITSAKV KYGLSDLFRV SILRRVTFCL SLAWFATGFA YYSLAMGVEE FGVNIYILQI 
IFGGVDIPAK FITILSISYL GRRITQGFLL ILAGVAILAL IFVSSEMQLL RTALAVFGKG 
CLSGSFSCLF LYTSELYPTV LRQTGMGISN IWARVGSMIA PLVKITGELQ PFIPNVIFGT 
MTLLGGSAAF FLLETLNRPL PETIEDIQDW YQQTKKTKQE PEAEKASQTI PLKTGGP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.