Details for: Rora

Gene ID: 19883

Symbol: Rora

Ensembl ID: ENSMUSG00000032238

Description: RAR-related orphan receptor alpha

Associated with

Other Information

Genular Protein ID: 3262392150

Symbol: RORA_MOUSE

Name: Nuclear receptor ROR-alpha

UniProtKB Accession Codes:

P51448 P70283 P97741 P97773 Q923G1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 47 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MGI 1 MINT 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 3 PRO 1 PROSITE 3 PROSITE-ProRule 2 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 2 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8602221

Title: Disruption of the nuclear hormone receptor RORalpha in staggerer mice.

PubMed ID: 8602221

DOI: 10.1038/379736a0

PubMed ID: 7935491

Title: RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers.

PubMed ID: 7935491

DOI: 10.1210/mend.8.6.7935491

PubMed ID: 9226375

Title: The structural integrity of ROR alpha isoforms is mutated in staggerer mice: cerebellar coexpression of ROR alpha1 and ROR alpha4.

PubMed ID: 9226375

DOI: 10.1006/geno.1997.4757

PubMed ID: 8750880

Title: An orphan nuclear receptor, mROR alpha, and its spatial expression in adult mouse brain.

PubMed ID: 8750880

DOI: 10.1016/0169-328x(95)00126-d

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11053433

Title: Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha.

PubMed ID: 11053433

DOI: 10.1074/jbc.m004982200

PubMed ID: 14687547

Title: RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.

PubMed ID: 14687547

DOI: 10.1016/s0896-6273(03)00769-4

PubMed ID: 15821743

Title: The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1.

PubMed ID: 15821743

DOI: 10.1038/nsmb925

PubMed ID: 17476214

Title: Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism.

PubMed ID: 17476214

DOI: 10.1038/nature05767

PubMed ID: 17666523

Title: Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism.

PubMed ID: 17666523

DOI: 10.1152/physiolgenomics.00098.2007

PubMed ID: 18055760

Title: Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3).

PubMed ID: 18055760

DOI: 10.1124/mol.107.040741

PubMed ID: 18535165

Title: The emerging role of nuclear receptor RORalpha and its crosstalk with LXR in xeno- and endobiotic gene regulation.

PubMed ID: 18535165

DOI: 10.3181/0802-mr-50

PubMed ID: 18164222

Title: T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma.

PubMed ID: 18164222

DOI: 10.1016/j.immuni.2007.11.016

PubMed ID: 18441015

Title: The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

PubMed ID: 18441015

DOI: 10.1074/jbc.m710526200

PubMed ID: 19039140

Title: Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease.

PubMed ID: 19039140

DOI: 10.1126/science.1164847

PubMed ID: 19014374

Title: Retinoic acid receptor-related orphan receptor alpha regulates a subset of cone genes during mouse retinal development.

PubMed ID: 19014374

DOI: 10.1111/j.1471-4159.2008.05739.x

PubMed ID: 19324970

Title: The orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expression.

PubMed ID: 19324970

DOI: 10.1210/me.2008-0277

PubMed ID: 19381306

Title: Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism.

PubMed ID: 19381306

DOI: 10.1621/nrs.07003

PubMed ID: 20300063

Title: Interaction of MAGED1 with nuclear receptors affects circadian clock function.

PubMed ID: 20300063

DOI: 10.1038/emboj.2010.34

PubMed ID: 20159955

Title: The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors.

PubMed ID: 20159955

DOI: 10.1101/gad.564110

PubMed ID: 19965867

Title: Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands.

PubMed ID: 19965867

DOI: 10.1074/jbc.m109.080614

PubMed ID: 21628546

Title: Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140).

PubMed ID: 21628546

DOI: 10.1177/0748730411401579

PubMed ID: 21499262

Title: Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.

PubMed ID: 21499262

DOI: 10.1038/nature10075

PubMed ID: 22170608

Title: Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.

PubMed ID: 22170608

DOI: 10.1038/nature10700

PubMed ID: 22753030

Title: RORgamma directly regulates the circadian expression of clock genes and downstream targets in vivo.

PubMed ID: 22753030

DOI: 10.1093/nar/gks630

PubMed ID: 22789990

Title: Action of RORs and their ligands in (patho)physiology.

PubMed ID: 22789990

DOI: 10.1016/j.tem.2012.05.012

PubMed ID: 23172836

Title: Pivotal role of Rho-associated kinase 2 in generating the intrinsic circadian rhythm of vascular contractility.

PubMed ID: 23172836

DOI: 10.1161/circulationaha.112.135608

PubMed ID: 23723244

Title: Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors alpha- and gamma-mediated transactivation.

PubMed ID: 23723244

DOI: 10.1093/nar/gkt447

Sequence Information:

  • Length: 523
  • Mass: 58845
  • Checksum: A194E02E4D9D177E
  • Sequence:
    • MESAPAAPDP AASEPGSSGS EAAAGSRETP LTQDTGRKSE APGAGRRQSY ASSSRGISVT 
KKTHTSQIEI IPCKICGDKS SGIHYGVITC EGCKGFFRRS QQSNATYSCP RQKNCLIDRT 
SRNRCQHCRL QKCLAVGMSR DAVKFGRMSK KQRDSLYAEV QKHRMQQQQR DHQQQPGEAE 
PLTPTYNISA NGLTELHDDL STYMDGHTPE GSKADSAVSS FYLDIQPSPD QSGLDINGIK 
PEPICDYTPA SGFFPYCSFT NGETSPTVSM AELEHLAQNI SKSHLETCQY LREELQQITW 
QTFLQEEIEN YQNKQREVMW QLCAIKITEA IQYVVEFAKR IDGFMELCQN DQIVLLKAGS 
LEVVFIRMCR AFDSQNNTVY FDGKYASPDV FKSLGCEDFI SFVFEFGKSL CSMHLTEDEI 
ALFSAFVLMS ADRSWLQEKV KIEKLQQKIQ LALQHVLQKN HREDGILTKL ICKVSTLRAL 
CGRHTEKLMA FKAIYPDIVR LHFPPLYKEL FTSEFEPAMQ IDG

Genular Protein ID: 809023679

Symbol: Q3U1P4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3U1P4

Database IDs:

AGR 1 ARBA 11 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 ExpressionAtlas 1 GO 4 Gene3D 2 Google 1 HOGENOM 1 InterPro 7 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 5 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 467
  • Mass: 53414
  • Checksum: 5621E275EC282A54
  • Sequence:
    • MYFVIAAMKA QIEIIPCKIC GDKSSGIHYG VITCEGCKGF FRRSQQSNAT YSCPRQKNCL 
IDRTSRNRCQ HCRLQKCLAV GMSRDAVKFG RMSKKQRDSL YAEVQKHRMQ QQQRDHQQQP 
GEAEPLTPTY NISANGLTEL HDDLSTYMDG HTPEGSKADS AVSSFYLDIQ PSPDQSGLDI 
NGIKPEPICD YTPASGFFPY CSFTNGETSP TVSMAELEHL AQNISKSHLE TCQYLREELQ 
QITWQTFLQE EIENYQNKQR EVMWQLCAIK ITEAIQYVVE FAKRIDGFME LCQNDQIVLL 
KAGSLEVVFI RMCRAFDSQN NTVYFDGKYA SPDVFKSLGC EDFISFVFEF GKSLCSMHLT 
EDEIALFSAF VLMSADRSWL QEKVKIEKLQ QKIQLALQHV LQKNHREDGI LTKLICKVST 
LRALCGRHTE KLMAFKAIYP DIVRLHFPPL YKELFTSEFE PAMQIDG

Genular Protein ID: 1369649309

Symbol: Q8C3F5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8C3F5

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Google 1 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 RefSeq 2 SAM 1 UCSC 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 79
  • Mass: 8258
  • Checksum: D61B91F3796E49C8
  • Sequence:
    • MESAPAAPDP AASEPGSSGS EAAAGSRETP LTQDTGRKSE APGAGRRQSY ASSSRGDFII 
SRHRHVSLKS RKENSQAKF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.