Genular: Defining Cellular Identity and Function

Details for: Rph3a

Gene ID: 19894

Symbol: Rph3a

Ensembl ID: ENSMUSG00000029608

Description: rabphilin 3A

Associated with

Calcium-dependent phospholipid binding
(GO:0005544)
Calcium ion binding
(GO:0005509)
Cell projection
(GO:0042995)
Cholinergic synapse
(GO:0098981)
Cytoplasmic vesicle
(GO:0031410)
Dendritic spine
(GO:0043197)
Dendritic spine organization
(GO:0097061)
Exocytosis
(GO:0006887)
Extrinsic component of membrane
(GO:0019898)
Extrinsic component of synaptic vesicle membrane
(GO:0098850)
Inositol 1,4,5 trisphosphate binding
(GO:0070679)
Intracellular protein transport
(GO:0006886)
Lipid binding
(GO:0008289)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Neuromuscular junction
(GO:0031594)
Neuron projection
(GO:0043005)
Phosphate ion binding
(GO:0042301)
Phosphatidylinositol-4,5-bisphosphate binding
(GO:0005546)
Plasma membrane
(GO:0005886)
Postsynaptic membrane
(GO:0045211)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein transport
(GO:0015031)
Regulation of calcium ion-dependent exocytosis
(GO:0017158)
Secretory granule
(GO:0030141)
Selenium binding
(GO:0008430)
Small gtpase binding
(GO:0031267)
Spontaneous neurotransmitter secretion
(GO:0061669)
Synapse
(GO:0045202)
Synaptic vesicle
(GO:0008021)
Synaptic vesicle membrane
(GO:0030672)
Synaptic vesicle priming
(GO:0016082)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Rabphilin-3A

Genular Protein ID: 3246750369

Symbol: RP3A_MOUSE

Name: Rabphilin-3A

UniProtKB Accession Codes:

P47708

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7822236

Title: Cloning of a mouse Rabphilin-3A expressed in hormone-secreting cells.

PubMed ID: 7822236

DOI: 10.1093/oxfordjournals.jbchem.a124512

PubMed ID: 10407024

Title: Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release.

PubMed ID: 10407024

DOI: 10.1523/jneurosci.19-14-05834.1999

PubMed ID: 12578829

Title: Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.

PubMed ID: 12578829

DOI: 10.1074/jbc.m212341200

PubMed ID: 17114649

Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PubMed ID: 17114649

DOI: 10.1074/mcp.m600046-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 18945677

Title: Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A.

PubMed ID: 18945677

DOI: 10.1074/jbc.m804094200

Sequence Information:

Length: 681
Mass: 75489
Checksum: D09F8D8D2CBB271E
Sequence:

MTDTVVNRWM YPGDGPLQSN DKEQLQAGWS VHPGAQTDRQ RKQEELTDEE KEIINRVIAR 
AEKMEAMEQE RIGRLVDRLE TMRKNVAGDG VNRCILCGEQ LGMLGSACVV CEDCKKNVCT 
KCGVETSNNR PHPVWLCKIC LEQREVWKRS GAWFFKGFPK QVLPQPMPIK KTKPQQPAGE 
PATQEQPTPE SRHPARAPAR GDMEDRRPPG QKPGPDLTSA PGRGSHGPPT RRASEARMST 
AARDSEGWDH AHGGGTGDTS RSPAGLRRAN SVQAARPAPA PVPSPAPPQP VQPGPPGGSR 
ATPGPGRFPE QSTEAPPSDP GYPGAVAPAR EERTGPAGGF QAAPHTAAPY SQAAPARQPP 
PAEEEEEEAN SYDSDEATTL GALEFSLLYD QDNSNLQCTI IRAKGLKPMD SNGLADPYVK 
LHLLPGASKS NKLRTKTLRN TRNPVWNETL QYHGITEEDM QRKTLRISVC DEDKFGHNEF 
IGETRFSLKK LKANQRKNFN ICLERVIPMK RAGTTGSARG MALYEEEQVE RIGDIEERGK 
ILVSLMYSTQ QGGLIVGIIR CVHLAAMDAN GYSDPFVKLW LKPDMGKKAK HKTQIKKKTL 
NPEFNEEFFY DIKHSDLAKK SLDISVWDYD IGKSNDYIGG CQLGISAKGE RLKHWYECLK 
NKDKKIERWH QLQNENHVSS D

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rph3a

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning of a mouse Rabphilin-3A expressed in hormone-secreting cells. PubMed ID: 7822236

Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release. PubMed ID: 10407024

Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. PubMed ID: 12578829

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. PubMed ID: 17114649

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A. PubMed ID: 18945677