Details for: ABCA2

Gene ID: 20

Symbol: ABCA2

Ensembl ID: ENSG00000107331

Description: ATP binding cassette subfamily A member 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 110.5788
    Cell Significance Index: -17.2000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 61.4248
    Cell Significance Index: -15.5800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 35.3471
    Cell Significance Index: -14.3600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 15.0198
    Cell Significance Index: -14.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 13.9664
    Cell Significance Index: -17.2200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.4389
    Cell Significance Index: -14.5700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.7990
    Cell Significance Index: -14.7400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.3841
    Cell Significance Index: -17.3000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.2441
    Cell Significance Index: -7.1000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0155
    Cell Significance Index: 203.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9887
    Cell Significance Index: 97.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7020
    Cell Significance Index: 31.8200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6754
    Cell Significance Index: 609.8300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.6219
    Cell Significance Index: 13.2500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5062
    Cell Significance Index: 82.3400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.4878
    Cell Significance Index: 13.9200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4381
    Cell Significance Index: 29.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4374
    Cell Significance Index: 156.9000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3895
    Cell Significance Index: 42.3700
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.2966
    Cell Significance Index: 2.2800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2651
    Cell Significance Index: 50.4600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2586
    Cell Significance Index: 178.8400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1877
    Cell Significance Index: 4.1100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1813
    Cell Significance Index: 5.2300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1687
    Cell Significance Index: 10.1300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1526
    Cell Significance Index: 10.5600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1515
    Cell Significance Index: 82.7200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1268
    Cell Significance Index: 25.1600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1220
    Cell Significance Index: 2.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0939
    Cell Significance Index: 6.0600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0715
    Cell Significance Index: 1.5500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0687
    Cell Significance Index: 4.2200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0546
    Cell Significance Index: 1.9200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0525
    Cell Significance Index: 6.7300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0478
    Cell Significance Index: 8.6200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0233
    Cell Significance Index: 10.3000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0101
    Cell Significance Index: 7.4100
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.0084
    Cell Significance Index: 0.0900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0049
    Cell Significance Index: 6.7300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0002
    Cell Significance Index: 0.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0001
    Cell Significance Index: -0.1800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0011
    Cell Significance Index: -0.1500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0014
    Cell Significance Index: -2.5600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0051
    Cell Significance Index: -9.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0137
    Cell Significance Index: -0.7200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0154
    Cell Significance Index: -9.8000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0207
    Cell Significance Index: -15.3200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0224
    Cell Significance Index: -16.9200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0239
    Cell Significance Index: -10.8400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0256
    Cell Significance Index: -14.4400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0308
    Cell Significance Index: -19.2300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0316
    Cell Significance Index: -1.6400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0500
    Cell Significance Index: -14.3900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0538
    Cell Significance Index: -6.6100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0560
    Cell Significance Index: -5.7300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0590
    Cell Significance Index: -8.5800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0602
    Cell Significance Index: -7.0100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0665
    Cell Significance Index: -11.3600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0746
    Cell Significance Index: -5.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0800
    Cell Significance Index: -3.5400
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0809
    Cell Significance Index: -0.7700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0878
    Cell Significance Index: -18.5000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0911
    Cell Significance Index: -11.7700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0938
    Cell Significance Index: -10.7500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1270
    Cell Significance Index: -3.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1336
    Cell Significance Index: -15.7500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1370
    Cell Significance Index: -7.6900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1398
    Cell Significance Index: -2.9000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1425
    Cell Significance Index: -10.0800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1444
    Cell Significance Index: -8.8600
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.1559
    Cell Significance Index: -2.1800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1590
    Cell Significance Index: -16.5600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1600
    Cell Significance Index: -6.0600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1723
    Cell Significance Index: -10.8600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1793
    Cell Significance Index: -4.3000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1842
    Cell Significance Index: -13.7300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1877
    Cell Significance Index: -8.8200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1885
    Cell Significance Index: -4.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1914
    Cell Significance Index: -15.1600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1995
    Cell Significance Index: -2.4800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2016
    Cell Significance Index: -5.1500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2116
    Cell Significance Index: -5.2900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2277
    Cell Significance Index: -11.8600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2437
    Cell Significance Index: -7.7600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2520
    Cell Significance Index: -5.0600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2816
    Cell Significance Index: -9.2200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2898
    Cell Significance Index: -5.7300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.2898
    Cell Significance Index: -4.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3010
    Cell Significance Index: -9.6400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3026
    Cell Significance Index: -10.5200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.3148
    Cell Significance Index: -4.2000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3172
    Cell Significance Index: -8.3400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3222
    Cell Significance Index: -3.5100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3233
    Cell Significance Index: -5.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3240
    Cell Significance Index: -8.8200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.3330
    Cell Significance Index: -2.8300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3460
    Cell Significance Index: -12.1200
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.3489
    Cell Significance Index: -2.8800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3504
    Cell Significance Index: -7.5700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3741
    Cell Significance Index: -10.0300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Lipid Transport:** ABCA2 is a transmembrane transporter that uses the energy from ATP hydrolysis to transport phospholipids and other lipids across cell membranes. 2. **Cholesterol Efflux:** ABCA2 is involved in the efflux of cholesterol from cells to high-density lipoprotein (HDL) particles, which is essential for maintaining cholesterol homeostasis. 3. **Myelin Formation:** ABCA2 is required for the formation of myelin in the central nervous system, a process critical for the transmission of nerve impulses. 4. **Regulation of Lipid Metabolism:** ABCA2 regulates various lipid metabolic processes, including sphingomyelin and sphingosine biosynthesis, glycosphingolipid metabolism, and lipid transport. **Pathways and Functions:** ABCA2 is involved in several key pathways, including: 1. **Abc-family proteins mediated transport:** ABCA2 is a member of the ABC family of transporters, which use ATP hydrolysis to transport lipids and other molecules across cell membranes. 2. **Abc-type transporter activity:** ABCA2 exhibits abc-type transporter activity, which involves the transport of phospholipids and other lipids across cell membranes. 3. **Lipid homeostasis:** ABCA2 regulates lipid homeostasis by modulating cholesterol efflux, sphingomyelin and sphingosine biosynthesis, and glycosphingolipid metabolism. 4. **Central nervous system myelin formation:** ABCA2 is required for the formation of myelin in the central nervous system, a process critical for nerve impulse transmission. **Clinical Significance:** Dysregulation of ABCA2 has been implicated in various diseases, including: 1. **Atherosclerosis:** ABCA2 has been shown to play a critical role in maintaining cholesterol homeostasis, and its dysregulation contributes to the development of atherosclerosis. 2. **Alzheimer's disease:** ABCA2 has been implicated in the pathogenesis of Alzheimer's disease, and its dysregulation contributes to the accumulation of amyloid-beta peptides. 3. **Multiple sclerosis:** ABCA2 is required for the formation of myelin in the central nervous system, and its dysregulation contributes to the development of multiple sclerosis. 4. **Xenobiotic metabolism:** ABCA2 regulates the metabolism of xenobiotics, and its dysregulation can lead to impaired detoxification processes. In conclusion, ABCA2 is a multifaceted gene involved in lipid metabolism and beyond. Its dysregulation has been implicated in various diseases, highlighting the importance of ABCA2 in maintaining cellular homeostasis and preventing disease. Further research is needed to fully elucidate the mechanisms by which ABCA2 regulates lipid metabolism and to develop therapeutic strategies for the treatment of ABCA2-related diseases.

Genular Protein ID: 111809873

Symbol: ABCA2_HUMAN

Name: ATP-binding cassette transporter 2

UniProtKB Accession Codes:

Q9BZC7 A6NED5 Q5SPY5 Q5W9G5 Q76MW7 Q9HC28

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 2 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 53 Ensembl 3 ExpressionAtlas 1 GO 51 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11178988

Title: Complete coding sequence, promoter region, and genomic structure of the human ABCA2 gene and evidence for sterol-dependent regulation in macrophages.

PubMed ID: 11178988

DOI: 10.1006/bbrc.2001.4305

PubMed ID: 11309290

Title: Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2.

PubMed ID: 11309290

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 15093135

Title: Identification of a novel first exon of the human ABCA2 transporter gene encoding a unique N-terminus.

PubMed ID: 15093135

DOI: 10.1016/j.bbaexp.2004.01.007

PubMed ID: 15238223

Title: Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells.

PubMed ID: 15238223

DOI: 10.1016/j.bbalip.2004.04.009

PubMed ID: 15999530

Title: Characterization of the ATPase activity of human ATP-binding cassette transporter-2 (ABCA2).

PubMed ID: 15999530

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21810484

Title: The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells.

PubMed ID: 21810484

DOI: 10.1016/j.bbalip.2011.07.010

PubMed ID: 22086926

Title: Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin maturation and intracellular localization.

PubMed ID: 22086926

DOI: 10.1074/jbc.m111.288258

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24201375

Title: The ATP-binding cassette transporter-2 (ABCA2) regulates esterification of plasma membrane cholesterol by modulation of sphingolipid metabolism.

PubMed ID: 24201375

DOI: 10.1016/j.bbalip.2013.10.019

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26510981

Title: The ATP-Binding Cassette Transporter-2 (ABCA2) Overexpression Modulates Sphingosine Levels and Transcription of the Amyloid Precursor Protein (APP) Gene.

PubMed ID: 26510981

DOI: 10.2174/156720501209151019105834

PubMed ID: 26797129

Title: Substrate specificity of the HEMK2 protein glutamine methyltransferase and identification of novel substrates.

PubMed ID: 26797129

DOI: 10.1074/jbc.m115.711952

PubMed ID: 29302074

Title: Genetics of intellectual disability in consanguineous families.

PubMed ID: 29302074

DOI: 10.1038/s41380-017-0012-2

PubMed ID: 30237576

Title: Autozygome and high throughput confirmation of disease genes candidacy.

PubMed ID: 30237576

DOI: 10.1038/s41436-018-0138-x

Sequence Information:

  • Length: 2435
  • Mass: 269833
  • Checksum: D707CC83F30BE2BF
  • Sequence:
    • MGFLHQLQLL LWKNVTLKRR SPWVLAFEIF IPLVLFFILL GLRQKKPTIS VKEAFYTAAP 
LTSAGILPVM QSLCPDGQRD EFGFLQYANS TVTQLLERLD RVVEEGNLFD PARPSLGSEL 
EALRQHLEAL SAGPGTSGSH LDRSTVSSFS LDSVARNPQE LWRFLTQNLS LPNSTAQALL 
AARVDPPEVY HLLFGPSSAL DSQSGLHKGQ EPWSRLGGNP LFRMEELLLA PALLEQLTCT 
PGSGELGRIL TVPESQKGAL QGYRDAVCSG QAAARARRFS GLSAELRNQL DVAKVSQQLG 
LDAPNGSDSS PQAPPPRRLQ ALLGDLLDAQ KVLQDVDVLS ALALLLPQGA CTGRTPGPPA 
SGAGGAANGT GAGAVMGPNA TAEEGAPSAA ALATPDTLQG QCSAFVQLWA GLQPILCGNN 
RTIEPEALRR GNMSSLGFTS KEQRNLGLLV HLMTSNPKIL YAPAGSEVDR VILKANETFA 
FVGNVTHYAQ VWLNISAEIR SFLEQGRLQQ HLRWLQQYVA ELRLHPEALN LSLDELPPAL 
RQDNFSLPSG MALLQQLDTI DNAACGWIQF MSKVSVDIFK GFPDEESIVN YTLNQAYQDN 
VTVFASVIFQ TRKDGSLPPH VHYKIRQNSS FTEKTNEIRR AYWRPGPNTG GRFYFLYGFV 
WIQDMMERAI IDTFVGHDVV EPGSYVQMFP YPCYTRDDFL FVIEHMMPLC MVISWVYSVA 
MTIQHIVAEK EHRLKEVMKT MGLNNAVHWV AWFITGFVQL SISVTALTAI LKYGQVLMHS 
HVVIIWLFLA VYAVATIMFC FLVSVLYSKA KLASACGGII YFLSYVPYMY VAIREEVAHD 
KITAFEKCIA SLMSTTAFGL GSKYFALYEV AGVGIQWHTF SQSPVEGDDF NLLLAVTMLM 
VDAVVYGILT WYIEAVHPGM YGLPRPWYFP LQKSYWLGSG RTEAWEWSWP WARTPRLSVM 
EEDQACAMES RRFEETRGME EEPTHLPLVV CVDKLTKVYK DDKKLALNKL SLNLYENQVV 
SFLGHNGAGK TTTMSILTGL FPPTSGSATI YGHDIRTEMD EIRKNLGMCP QHNVLFDRLT 
VEEHLWFYSR LKSMAQEEIR REMDKMIEDL ELSNKRHSLV QTLSGGMKRK LSVAIAFVGG 
SRAIILDEPT AGVDPYARRA IWDLILKYKP GRTILLSTHH MDEADLLGDR IAIISHGKLK 
CCGSPLFLKG TYGDGYRLTL VKRPAEPGGP QEPGLASSPP GRAPLSSCSE LQVSQFIRKH 
VASCLLVSDT STELSYILPS EAAKKGAFER LFQHLERSLD ALHLSSFGLM DTTLEEVFLK 
VSEEDQSLEN SEADVKESRK DVLPGAEGPA SGEGHAGNLA RCSELTQSQA SLQSASSVGS 
ARGDEGAGYT DVYGDYRPLF DNPQDPDNVS LQEVEAEALS RVGQGSRKLD GGWLKVRQFH 
GLLVKRFHCA RRNSKALFSQ ILLPAFFVCV AMTVALSVPE IGDLPPLVLS PSQYHNYTQP 
RGNFIPYANE ERREYRLRLS PDASPQQLVS TFRLPSGVGA TCVLKSPANG SLGPTLNLSS 
GESRLLAARF FDSMCLESFT QGLPLSNFVP PPPSPAPSDS PASPDEDLQA WNVSLPPTAG 
PEMWTSAPSL PRLVREPVRC TCSAQGTGFS CPSSVGGHPP QMRVVTGDIL TDITGHNVSE 
YLLFTSDRFR LHRYGAITFG NVLKSIPASF GTRAPPMVRK IAVRRAAQVF YNNKGYHSMP 
TYLNSLNNAI LRANLPKSKG NPAAYGITVT NHPMNKTSAS LSLDYLLQGT DVVIAIFIIV 
AMSFVPASFV VFLVAEKSTK AKHLQFVSGC NPIIYWLANY VWDMLNYLVP ATCCVIILFV 
FDLPAYTSPT NFPAVLSLFL LYGWSITPIM YPASFWFEVP SSAYVFLIVI NLFIGITATV 
ATFLLQLFEH DKDLKVVNSY LKSCFLIFPN YNLGHGLMEM AYNEYINEYY AKIGQFDKMK 
SPFEWDIVTR GLVAMAVEGV VGFLLTIMCQ YNFLRRPQRM PVSTKPVEDD VDVASERQRV 
LRGDADNDMV KIENLTKVYK SRKIGRILAV DRLCLGVRPG ECFGLLGVNG AGKTSTFKML 
TGDESTTGGE AFVNGHSVLK ELLQVQQSLG YCPQCDALFD ELTAREHLQL YTRLRGISWK 
DEARVVKWAL EKLELTKYAD KPAGTYSGGN KRKLSTAIAL IGYPAFIFLD EPTTGMDPKA 
RRFLWNLILD LIKTGRSVVL TSHSMEECEA LCTRLAIMVN GRLRCLGSIQ HLKNRFGDGY 
MITVRTKSSQ SVKDVVRFFN RNFPEAMLKE RHHTKVQYQL KSEHISLAQV FSKMEQVSGV 
LGIEDYSVSQ TTLDNVFVNF AKKQSDNLEQ QETEPPSALQ SPLGCLLSLL RPRSAPTELR 
ALVADEPEDL DTEDEGLISF EEERAQLSFN TDTLC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.