Genular: Defining Cellular Identity and Function

Details for: Rps6ka2

Gene ID: 20112

Symbol: Rps6ka2

Ensembl ID: ENSMUSG00000023809

Description: ribosomal protein S6 kinase, polypeptide 2

Associated with

Activation of nmda receptors and postsynaptic events
(R-MMU-442755)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular senescence
(R-MMU-2559583)
Creb1 phosphorylation through nmda receptor-mediated activation of ras signaling
(R-MMU-442742)
Creb phosphorylation
(R-MMU-199920)
Cytokine signaling in immune system
(R-MMU-1280215)
Erk/mapk targets
(R-MMU-198753)
G alpha (q) signalling events
(R-MMU-416476)
Gastrin-creb signalling pathway via pkc and mapk
(R-MMU-881907)
Gpcr downstream signalling
(R-MMU-388396)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Interleukin-17 signaling
(R-MMU-448424)
Map kinase activation
(R-MMU-450294)
Mapk targets/ nuclear events mediated by map kinases
(R-MMU-450282)
Myd88 cascade initiated on plasma membrane
(R-MMU-975871)
Myd88 dependent cascade initiated on endosome
(R-MMU-975155)
Myd88-independent tlr4 cascade
(R-MMU-166166)
Myd88:mal(tirap) cascade initiated on plasma membrane
(R-MMU-166058)
Neuronal system
(R-MMU-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-MMU-112314)
Nuclear events (kinase and transcription factor activation)
(R-MMU-198725)
Post nmda receptor activation events
(R-MMU-438064)
Rsk activation
(R-MMU-444257)
Senescence-associated secretory phenotype (sasp)
(R-MMU-2559582)
Signaling by gpcr
(R-MMU-372790)
Signaling by interleukins
(R-MMU-449147)
Signaling by ntrk1 (trka)
(R-MMU-187037)
Signaling by ntrks
(R-MMU-166520)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Toll-like receptor cascades
(R-MMU-168898)
Toll like receptor 2 (tlr2) cascade
(R-MMU-181438)
Toll like receptor 3 (tlr3) cascade
(R-MMU-168164)
Toll like receptor 4 (tlr4) cascade
(R-MMU-166016)
Toll like receptor 5 (tlr5) cascade
(R-MMU-168176)
Toll like receptor 7/8 (tlr7/8) cascade
(R-MMU-168181)
Toll like receptor 9 (tlr9) cascade
(R-MMU-168138)
Toll like receptor 10 (tlr10) cascade
(R-MMU-168142)
Toll like receptor tlr1:tlr2 cascade
(R-MMU-168179)
Toll like receptor tlr6:tlr2 cascade
(R-MMU-168188)
Traf6 mediated induction of nfkb and map kinases upon tlr7/8 or 9 activation
(R-MMU-975138)
Transmission across chemical synapses
(R-MMU-112315)
Trif(ticam1)-mediated tlr4 signaling
(R-MMU-937061)
Atp binding
(GO:0005524)
Brain renin-angiotensin system
(GO:0002035)
Cardiac muscle cell apoptotic process
(GO:0010659)
Cellular response to carbohydrate stimulus
(GO:0071322)
Cytoplasm
(GO:0005737)
Heart contraction
(GO:0060047)
Heart development
(GO:0007507)
Intracellular signal transduction
(GO:0035556)
Kinase activity
(GO:0016301)
Magnesium ion binding
(GO:0000287)
Meiotic spindle
(GO:0072687)
Negative regulation of cell cycle
(GO:0045786)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of meiotic nuclear division
(GO:0045835)
Nucleoplasm
(GO:0005654)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Oocyte maturation
(GO:0001556)
Peptidyl-serine phosphorylation
(GO:0018105)
Phosphorylation
(GO:0016310)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of gene expression
(GO:0010628)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein serine/threonine/tyrosine kinase activity
(GO:0004712)
Protein serine/threonine kinase activity
(GO:0004674)
Regulation of protein processing
(GO:0070613)
Ribosomal protein s6 kinase activity
(GO:0004711)
Spindle
(GO:0005819)
Transferase activity
(GO:0016740)

Other Information

Proteins

Ribosomal protein S6 kinase alpha-2
Q7TPD5_MOUSE

Genular Protein ID: 1228516721

Symbol: KS6A2_MOUSE

Name: Ribosomal protein S6 kinase alpha-2

UniProtKB Accession Codes:

Q9WUT3 Q9D2C0

Database IDs:

Citations:

PubMed ID: 10430666

Title: The mouse Rsk3 gene maps to the Leh66 elements carrying the T-complex responder Tcr.

PubMed ID: 10430666

DOI: 10.1007/s003359901094

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1281307

Title: An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain.

PubMed ID: 1281307

PubMed ID: 15526037

Title: Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes.

PubMed ID: 15526037

DOI: 10.1038/sj.emboj.7600448

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 733
Mass: 83157
Checksum: 49C1390316CFCE91
Sequence:

MELSMKKFTV RRFFSVYLRK KSRSKSSSLS RLEEEGIVKE IDISNHVKEG FEKADPSQFE 
LLKVLGQGSY GKVFLVRKVT GSDAGQLYAM KVLKKATLKV RDRVRSKMER DILAEVNHPF 
IVKLHYAFQT EGKLYLILDF LRGGDLFTRL SKEVMFTEED VKFYLAELAL ALDHLHGLGI 
IYRDLKPENI LLDEEGHIKI TDFGLSKEAT DHDKRAYSFC GTIEYMAPEV VNRRGHTQSA 
DWWSFGVLMF EMLTGSLPFQ GKDRKETMAL ILKAKLGMPQ FLSAEAQSLL RALFKRNPCN 
RLGAGVDGVE EIKRHPFFVT IDWNKLYRKE IKPPFKPAVG RPEDTFHFDP EFTARTPTDS 
PGVPPSANAH HLFRGFSFVA SSLVQEPSQQ DVPKAPIHPI VQQLHGNNIH FTDGYEIKED 
IGVGSYSVCK RCVHKATDAE YAVKIIDKSK RDPSEEIEIL LRYGQHPNII TLKDVYDDGK 
YVYLVMELMR GGELLDRILR QRCFSEREAS DVLYTIARTM DYLHSQGVVH RDLKPSNILY 
MDESGNPESI RICDFGFAKQ LRAENGLLMT PCYTANFVAP EVLKRQGYDA ACDVWSLGIL 
LYTMLAGFTP FANGPDDTPE EILARIGSGK YALSGGNWDS ISDAAKDVVS KMLHVDPQQR 
LTAVQVLKHP WIVNREYLSQ NQLSRQDVHL VKGAMAATYF ALNRTPQAPR LEPVLSSSLA 
QRRGMKRLTS TRL

Genular Protein ID: 2482728361

Symbol: Q7TPD5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q7TPD5

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 733
Mass: 83187
Checksum: 82A03EB57F8E3E16
Sequence:

MELSMKKFTV RRFFSVYLRK KSRSKSSSLS RLEEEGIVKE IDISNHVKEG FEKADPSQFE 
LLKVLGQGSY GKVFLVRKVT GSDAGQLYTM KVLKKATLKV RDRVRSKMER DILAEVNHPF 
IVKLHYAFQT EGKLYLILDF LRGGDLFTRL SKEVMFTEED VKFYLAELAL ALDHLHGLGI 
IYRDLKPENI LLDEEGHIKI TDFGLSKEAT DHDKRAYSFC GTIEYMAPEV VNRRGHTQSA 
DWWSFGVLMF EMLTGSLPFQ GKDRKETMAL ILKAKLGMPQ FLSAEAQSLL RALFKRNPCN 
RLGAGVDGVE EIKRHPFFVT IDWNKLYRKE IKPPFKPAVG RPEDTFHFDP EFTARTPTDS 
PGVPPSANAH HLFRGFSFVA SSLVQEPSQQ DVPKAPIHPI VQQLHGNNIH FTDGYEIKED 
IGVGSYSVCK RCVHKATDAE YAVKIIDKSK RDPSEEIEIL LRYGQHPNII TLKDVYDDGK 
YVYLVMELMR GGELLDRILR QRCFSEREAS DVLYTIARTM DYLHSQGVVH RDLKPSNILY 
MDESGNPESI RICDFGFAKQ LRAENGLLMT PCYTANFVAP EVLKRQGYDA ACDVWSLGIL 
LYTMLAGFTP FANGPDDTPE EILARIGSGK YALSGGNWDS ISDAAKDVVS KMLHVDPQQR 
LTAVQVLKHP WIVNREYLSQ NQLSRQDVHL VKGAMAATYF ALNRTPQAPR LEPVLSSSLA 
QRRGMKRLTS TRL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rps6ka2

Associated with

Other Information

The mouse Rsk3 gene maps to the Leh66 elements carrying the T-complex responder Tcr. PubMed ID: 10430666

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain. PubMed ID: 1281307

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes. PubMed ID: 15526037

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 10430666

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 1281307

PubMed ID: 15526037

PubMed ID: 15345747

PubMed ID: 21183079

PubMed ID: 15489334