Genular: Defining Cellular Identity and Function

Details for: Trim30a

Gene ID: 20128

Symbol: Trim30a

Ensembl ID: ENSMUSG00000030921

Description: tripartite motif-containing 30A

Associated with

Activation of innate immune response
(GO:0002218)
Autophagy
(GO:0006914)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dna binding
(GO:0003677)
Identical protein binding
(GO:0042802)
Innate immune response
(GO:0045087)
Metal ion binding
(GO:0046872)
Negative regulation of interleukin-6 production
(GO:0032715)
Negative regulation of nlrp3 inflammasome complex assembly
(GO:1900226)
Negative regulation of reactive oxygen species metabolic process
(GO:2000378)
Negative regulation of toll-like receptor signaling pathway
(GO:0034122)
Negative regulation of tumor necrosis factor production
(GO:0032720)
Negative regulation of viral entry into host cell
(GO:0046597)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Omegasome
(GO:1990462)
P-body
(GO:0000932)
Pattern recognition receptor activity
(GO:0038187)
Positive regulation of autophagy
(GO:0010508)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Positive regulation of protein catabolic process
(GO:0045732)
Positive regulation of viral entry into host cell
(GO:0046598)
Protein-macromolecule adaptor activity
(GO:0030674)
Protein autoubiquitination
(GO:0051865)
Protein homodimerization activity
(GO:0042803)
Protein k63-linked ubiquitination
(GO:0070534)
Protein kinase binding
(GO:0019901)
Protein polyubiquitination
(GO:0000209)
Regulation of lipopolysaccharide-mediated signaling pathway
(GO:0031664)
Regulation of protein localization
(GO:0032880)
Regulation of viral entry into host cell
(GO:0046596)
Response to bacterium
(GO:0009617)
Suppression of viral release by host
(GO:0044790)
Transcription coactivator activity
(GO:0003713)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Tripartite motif-containing protein 30A

Genular Protein ID: 2745750240

Symbol: TR30A_MOUSE

Name: Tripartite motif-containing protein 30A

UniProtKB Accession Codes:

P15533 Q3UV85 Q3UZ29 Q99K55 Q99PQ7 Q99PQ8 Q99PQ9

Database IDs:

Citations:

PubMed ID: 2965815

Title: rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1.

PubMed ID: 2965815

DOI: 10.1073/pnas.85.8.2733

PubMed ID: 11331580

Title: The tripartite motif family identifies cell compartments.

PubMed ID: 11331580

DOI: 10.1093/emboj/20.9.2140

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18345001

Title: TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation.

PubMed ID: 18345001

DOI: 10.1038/ni1577

PubMed ID: 19147168

Title: An expanded clade of rodent Trim5 genes.

PubMed ID: 19147168

DOI: 10.1016/j.virol.2008.12.018

PubMed ID: 21048113

Title: Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

PubMed ID: 21048113

DOI: 10.4049/jimmunol.1001099

Sequence Information:

Length: 496
Mass: 57330
Checksum: 66502B93BDC3A1D2
Sequence:

MASSVLEMIK EEVTCPICLE LLKEPVSADC NHSFCRACIT LNYESNRNTD GKGNCPVCRV 
PYPFGNLRPN LHVANIVERL KGFKSIPEEE QKVNICAQHG EKLRLFCRKD MMVICWLCER 
SQEHRGHQTA LIEEVDQEYK EKLQGALWKL MKKAKICDEW QDDLQLQRVD WENQIQINVE 
NVQRQFKGLR DLLDSKENEE LQKLKKEKKE VMEKLEESEN ELEDQTELVR DLISDVEHHL 
ELSTLEMLQG ANCVLRRSQS LSLQQPQTVP QKRKRTFQAP DLKGMLQVYQ GLMDIQQYWV 
HMTLHARNNA VIAINKEKRQ IQYRSYNTVP VSEIYHLGVL GYPALSSGKH YWEVDISRSD 
AWLLGLNDGK CAQPQLHSKE EMGIKKNLHS QIKQNVLFQP KCGYWVIGMK NPSVYKAFDE 
CSITHNSSIL VISLPDRPSR VGVFLDRKAG TLSFYDVSNC GALIYRFYDP AFPVEVYPYF 
NPMKCSEPMT ICGPPS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Trim30a

Associated with

Other Information

rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1. PubMed ID: 2965815

The tripartite motif family identifies cell compartments. PubMed ID: 11331580

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation. PubMed ID: 18345001

An expanded clade of rodent Trim5 genes. PubMed ID: 19147168

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production. PubMed ID: 21048113