Genular: Defining Cellular Identity and Function

Details for: Rrm1

Gene ID: 20133

Symbol: Rrm1

Ensembl ID: ENSMUSG00000030978

Description: ribonucleotide reductase M1

Associated with

Interconversion of nucleotide di- and triphosphates
(R-MMU-499943)
Metabolism
(R-MMU-1430728)
Metabolism of nucleotides
(R-MMU-15869)
2'-deoxyribonucleotide biosynthetic process
(GO:0009265)
Atp binding
(GO:0005524)
Catalytic activity
(GO:0003824)
Cell projection
(GO:0042995)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Deoxyribonucleotide biosynthetic process
(GO:0009263)
Disordered domain specific binding
(GO:0097718)
Dna repair
(GO:0006281)
Dna replication
(GO:0006260)
Dna synthesis involved in dna repair
(GO:0000731)
Identical protein binding
(GO:0042802)
Metabolic process
(GO:0008152)
Mitochondrial dna replication
(GO:0006264)
Neuronal cell body
(GO:0043025)
Nuclear envelope
(GO:0005635)
Nucleotide binding
(GO:0000166)
Oxidoreductase activity
(GO:0016491)
Positive regulation of g0 to g1 transition
(GO:0070318)
Positive regulation of g1/s transition of mitotic cell cycle
(GO:1900087)
Positive regulation of g2/m transition of mitotic cell cycle
(GO:0010971)
Protein binding
(GO:0005515)
Protein heterotetramerization
(GO:0051290)
Purine nucleotide binding
(GO:0017076)
Ribonucleoside-diphosphate reductase activity
(GO:0061731)
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
(GO:0004748)
Ribonucleoside-diphosphate reductase complex
(GO:0005971)
Ribonucleoside diphosphate metabolic process
(GO:0009185)

Other Information

Proteins

Ribonucleoside-diphosphate reductase large subunit

Genular Protein ID: 3967927738

Symbol: RIR1_MOUSE

Name: Ribonucleoside-diphosphate reductase large subunit

UniProtKB Accession Codes:

P07742 Q91YM8

Database IDs:

Citations:

PubMed ID: 2581962

Title: Cloned mouse ribonucleotide reductase subunit M1 cDNA reveals amino acid sequence homology with Escherichia coli and herpesvirus ribonucleotide reductases.

PubMed ID: 2581962

DOI: 10.1016/s0021-9258(18)88881-0

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19176520

Title: Molecular mechanisms of thioredoxin and glutaredoxin as hydrogen donors for mammalian S phase ribonucleotide reductase.

PubMed ID: 19176520

DOI: 10.1074/jbc.m809338200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 792
Mass: 90210
Checksum: 051C6CE407D24C69
Sequence:

MHVIKRDGRQ ERVMFDKITS RIQKLCYGLN MDFVDPAQIT MKVIQGLYSG VTTVELDTLA 
AETAATLTTK HPDYAILAAR IAVSNLHKET KKVFSDVMED LYNYINPHNG RHSPMVASST 
LDIVMANKDR LNSAIIYDRD FSYNYFGFKT LERSYLLKIN GKVAERPQHM LMRVSVGIHK 
EDIDAAIETY NLLSEKWFTH ASPTLFNAGT NRPQLSSCFL LSMKDDSIEG IYDTLKQCAL 
ISKSAGGIGV AVSCIRATGS YIAGTNGNSN GLVPMLRVYN NTARYVDQGG NKRPGAFAIY 
LEPWHLDIFE FLDLKKNTGK EEQRARDLFF ALWIPDLFMK RVETNQDWSL MCPNECPGLD 
EVWGEEFEKL YESYEKQGRV RKVVKAQQLW YAIIESQTET GTPYMLYKDS CNRKSNQQNL 
GTIKCSNLCT EIVEYTSKDE VAVCNLASLA LNMYVTPEHT YDFEKLAEVT KVIVRNLNKI 
IDINYYPIPE AHLSNKRHRP IGIGVQGLAD AFILMRYPFE SPEAQLLNKQ IFETIYYGAL 
EASCELAKEY GPYETYEGSP VSKGILQYDM WNVAPTDLWD WKPLKEKIAK YGIRNSLLIA 
PMPTASTAQI LGNNESIEPY TSNIYTRRVL SGEFQIVNPH LLKDLTERGL WNEEMKNQII 
ACNGSIQSIP EIPDDLKQLY KTVWEISQKT VLKMAAERGA FIDQSQSLNI HIAEPNYGKL 
TSMHFYGWKQ GLKTGMYYLR TRPAANPIQF TLNKEKLKDK EKALKEEEEK ERNTAAMVCS 
LENREECLMC GS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rrm1

Associated with

Other Information

Cloned mouse ribonucleotide reductase subunit M1 cDNA reveals amino acid sequence homology with Escherichia coli and herpesvirus ribonucleotide reductases. PubMed ID: 2581962

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334