Genular: Defining Cellular Identity and Function

Details for: Rs1

Gene ID: 20147

Symbol: Rs1

Ensembl ID: ENSMUSG00000031293

Description: retinoschisis (X-linked, juvenile) 1 (human)

Associated with

Adaptation of rhodopsin mediated signaling
(GO:0016062)
Cell adhesion
(GO:0007155)
Cell surface
(GO:0009986)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Lipid binding
(GO:0008289)
Membrane
(GO:0016020)
Neuron to neuron synapse
(GO:0098984)
Phosphatidylcholine binding
(GO:0031210)
Phosphatidylethanolamine binding
(GO:0008429)
Phosphatidylinositol-3,4,5-trisphosphate binding
(GO:0005547)
Phosphatidylinositol-3,4-bisphosphate binding
(GO:0043325)
Phosphatidylinositol-3,5-bisphosphate binding
(GO:0080025)
Phosphatidylinositol-3-phosphate binding
(GO:0032266)
Phosphatidylinositol-4,5-bisphosphate binding
(GO:0005546)
Phosphatidylinositol-4-phosphate binding
(GO:0070273)
Phosphatidylinositol-5-phosphate binding
(GO:0010314)
Phosphatidylserine binding
(GO:0001786)
Photoreceptor inner segment
(GO:0001917)
Plasma membrane
(GO:0005886)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein homooligomerization
(GO:0051260)
Response to stimulus
(GO:0050896)
Retina layer formation
(GO:0010842)
Visual perception
(GO:0007601)

Other Information

Proteins

Retinoschisin

Genular Protein ID: 759128425

Symbol: XLRS1_MOUSE

Name: Retinoschisin

UniProtKB Accession Codes:

Q9Z1L4

Database IDs:

Citations:

PubMed ID: 10051329

Title: Isolation and characterization of the murine X-linked juvenile retinoschisis (Rs1h) gene.

PubMed ID: 10051329

DOI: 10.1007/s003359900991

PubMed ID: 10023077

Title: The mouse X-linked juvenile retinoschisis cDNA: expression in photoreceptors.

PubMed ID: 10023077

DOI: 10.1016/s0378-1119(98)00578-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10915776

Title: Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells.

PubMed ID: 10915776

DOI: 10.1093/hmg/9.12.1873

PubMed ID: 11983912

Title: Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure.

PubMed ID: 11983912

DOI: 10.1073/pnas.092528599

PubMed ID: 17325137

Title: Retinoschisin is a peripheral membrane protein with affinity for anionic phospholipids and affected by divalent cations.

PubMed ID: 17325137

DOI: 10.1167/iovs.06-0915

PubMed ID: 20677810

Title: Retinoschisin (RS1) interacts with negatively charged lipid bilayers in the presence of Ca2+: an atomic force microscopy study.

PubMed ID: 20677810

DOI: 10.1021/bi1007029

Sequence Information:

Length: 224
Mass: 25575
Checksum: 4536203CC00E90E4
Sequence:

MPHKIEGFFL LLLFGYEATL GLSSTEDEGE DPWYQKACKC DCQVGANALW SAGATSLDCI 
PECPYHKPLG FESGEVTPDQ ITCSNPEQYV GWYSSWTANK ARLNSQGFGC AWLSKYQDSS 
QWLQIDLKEI KVISGILTQG RCDIDEWVTK YSVQYRTDER LNWIYYKDQT GNNRVFYGNS 
DRSSTVQNLL RPPIISRFIR LIPLGWHVRI AIRMELLECA SKCA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rs1

Associated with

Other Information

Isolation and characterization of the murine X-linked juvenile retinoschisis (Rs1h) gene. PubMed ID: 10051329

The mouse X-linked juvenile retinoschisis cDNA: expression in photoreceptors. PubMed ID: 10023077

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells. PubMed ID: 10915776

Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure. PubMed ID: 11983912

Retinoschisin is a peripheral membrane protein with affinity for anionic phospholipids and affected by divalent cations. PubMed ID: 17325137

Retinoschisin (RS1) interacts with negatively charged lipid bilayers in the presence of Ca2+: an atomic force microscopy study. PubMed ID: 20677810