Details for: Hps6

Gene ID: 20170

Symbol: Hps6

Ensembl ID: ENSMUSG00000074811

Description: HPS6, biogenesis of lysosomal organelles complex 2 subunit 3

Associated with

Other Information

Genular Protein ID: 644519557

Symbol: HPS6_MOUSE

Name: Hermansky-Pudlak syndrome 6 protein homolog

UniProtKB Accession Codes:

Q8BLY7 Q3TWQ8 Q8BML5 Q8CIA3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CORUM 1 CTD 1 ComplexPortal 1 EMBL 5 EPD 1 Ensembl 1 GO 16 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 12548288

Title: Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6.

PubMed ID: 12548288

DOI: 10.1038/ng1087

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19010779

Title: Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.

PubMed ID: 19010779

DOI: 10.1074/jbc.m805991200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25189619

Title: HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes.

PubMed ID: 25189619

DOI: 10.1242/jcs.141978

Sequence Information:

  • Length: 805
  • Mass: 87341
  • Checksum: 503BCD0B3760D95A
  • Sequence:
    • MKRAGTLRLL SDLSNFTGAA RLRELLAGDP AVLVRCSPDG RHLLLLRPPG SPAPQLLVAV 
RGPGLPLERA WPEGDPSPLD VFFVPWLARP ALILVWESGL AEVWGVGMEP GWKLLQSTEL 
CPDGGARVMA VAATRGRLVW CEERQPGVKD QPEQLSTAFS HRVCFKTLET SGEAGTKLGC 
THILLHHCPL FGLIASRKDL FLVPTTNTWS GVAHLLLIWS PSKGKVIVAA PSLGLSHSKS 
LNPKQGDTWD FRTLLRGLPG FLSPREPLAV HTWAPSSQGL LLLDLKGKVS LVQCHGGTRT 
VGILQEAPVS LKGSAALGTF HGTLACVLGS TLELLDMSSG RLLEKKVLST DRVHLLEPPA 
PGMKNEEELE TRGALRLLSA LGLFCVCWET PQGLELPSDK DLVFEEACGY YQRRSLRGTQ 
LTPEELRHNS MFRAPQALAS ILQGHLPPST LLTTLRAELR DYRSIEQLKA QLVAGDDEEA 
GWTELAEHEV ARLLRTQLTG DQLAQFNTIF QALPTAAWGA TLQALQLQPD RSGRLRSQAP 
PDVWKKVLRA PTAGKEHPNG ILPPFELLCQ CLGQLEPQWL PPFVKLAQQQ GGPGWGAEGP 
SLPLYRRALA VLGEEGKRPE ALELELLLGS GRPKAVLQAV RQLIKKEEWE RALEAGLALD 
ASSPLLRSEI FKLLLAEFAQ HRRLDAHLPL LCRLCPPEVA PHELLLLLRT HLPDDEGTTP 
FPEPGAEPPL TVGLVRALLE QTGAQGRPSG PVQSTYEDIL WDPGTPPPTP PRGPTASLPA 
SDHPGQEAWV PPGQGLGAAD VGVHL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.