Details for: Scd1
Associated with
Other Information
Genular Protein ID: 2128338192
Symbol: ACOD1_MOUSE
Name: Fatty acid desaturase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2903162
Title: Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase.
PubMed ID: 2903162
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17738154
Title: Hereditary absence of sebaceous glands in the mouse.
PubMed ID: 17738154
PubMed ID: 10545940
Title: Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
PubMed ID: 10545940
DOI: 10.1038/15446
PubMed ID: 10854228
Title: Asebia-2J (Scd1(ab2J)): a new allele and a model for scarring alopecia.
PubMed ID: 10854228
PubMed ID: 10899171
Title: The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1.
PubMed ID: 10899171
PubMed ID: 11161812
Title: Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin.
PubMed ID: 11161812
PubMed ID: 11500518
Title: Oleoyl-CoA is the major de novo product of stearoyl-CoA desaturase 1 gene isoform and substrate for the biosynthesis of the Harderian gland 1-alkyl-2,3-diacylglycerol.
PubMed ID: 11500518
PubMed ID: 11441127
Title: A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis.
PubMed ID: 11441127
PubMed ID: 11533264
Title: Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid.
PubMed ID: 11533264
PubMed ID: 12177411
Title: Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity.
PubMed ID: 12177411
PubMed ID: 12815040
Title: Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors.
PubMed ID: 12815040
PubMed ID: 15210843
Title: Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment.
PubMed ID: 15210843
PubMed ID: 15278437
Title: Scd1ab-Xyk: a new asebia allele characterized by a CCC trinucleotide insertion in exon 5 of the stearoyl-CoA desaturase 1 gene in mouse.
PubMed ID: 15278437
PubMed ID: 16275639
Title: Membrane topology of mouse stearoyl-CoA desaturase 1.
PubMed ID: 16275639
PubMed ID: 16443825
Title: Identification of mouse palmitoyl-coenzyme A Delta9-desaturase.
PubMed ID: 16443825
PubMed ID: 17127673
Title: Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat.
PubMed ID: 17127673
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 24356954
Title: Role of stearoyl-CoA desaturase-1 in skin integrity and whole body energy balance.
PubMed ID: 24356954
PubMed ID: 24295027
Title: Opportunities and challenges in developing stearoyl-coenzyme A desaturase-1 inhibitors as novel therapeutics for human disease.
PubMed ID: 24295027
DOI: 10.1021/jm401516c
PubMed ID: 26098370
Title: X-ray structure of a mammalian stearoyl-CoA desaturase.
PubMed ID: 26098370
DOI: 10.1038/nature14549
Sequence Information:
- Length: 355
- Mass: 41046
- Checksum: 00E2348C1898FE75
- Sequence:
MPAHMLQEIS SSYTTTTTIT APPSGNEREK VKTVPLHLEE DIRPEMKEDI HDPTYQDEEG PPPKLEYVWR NIILMVLLHL GGLYGIILVP SCKLYTCLFG IFYYMTSALG ITAGAHRLWS HRTYKARLPL RIFLIIANTM AFQNDVYEWA RDHRAHHKFS ETHADPHNSR RGFFFSHVGW LLVRKHPAVK EKGGKLDMSD LKAEKLVMFQ RRYYKPGLLL MCFILPTLVP WYCWGETFVN SLFVSTFLRY TLVLNATWLV NSAAHLYGYR PYDKNIQSRE NILVSLGAVG EGFHNYHHTF PFDYSASEYR WHINFTTFFI DCMAALGLAY DRKKVSKATV LARIKRTGDG SHKSS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.