Genular: Defining Cellular Identity and Function

Details for: Scd2

Gene ID: 20250

Symbol: Scd2

Ensembl ID: ENSMUSG00000025203

Description: stearoyl-Coenzyme A desaturase 2

Associated with

Fatty acid metabolism
(R-MMU-8978868)
Fatty acyl-coa biosynthesis
(R-MMU-75105)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Fatty acid biosynthetic process
(GO:0006633)
Fatty acid metabolic process
(GO:0006631)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Monounsaturated fatty acid biosynthetic process
(GO:1903966)
Nucleolus
(GO:0005730)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
(GO:0016717)
Palmitoyl-coa 9-desaturase activity
(GO:0032896)
Response to fatty acid
(GO:0070542)
Stearoyl-coa 9-desaturase activity
(GO:0004768)
Unsaturated fatty acid biosynthetic process
(GO:0006636)

Other Information

Proteins

Acyl-CoA desaturase 2

Genular Protein ID: 174662295

Symbol: SCD2_MOUSE

Name: Acyl-CoA desaturase 2

UniProtKB Accession Codes:

P13011 Q8BH96

Database IDs:

Citations:

PubMed ID: 2570068

Title: Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase.

PubMed ID: 2570068

DOI: 10.1016/s0021-9258(18)63763-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10545940

Title: Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.

PubMed ID: 10545940

DOI: 10.1038/15446

PubMed ID: 11161812

Title: Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin.

PubMed ID: 11161812

DOI: 10.1006/geno.2000.6429

PubMed ID: 12815040

Title: Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors.

PubMed ID: 12815040

DOI: 10.1074/jbc.m304724200

PubMed ID: 16118274

Title: Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development.

PubMed ID: 16118274

DOI: 10.1073/pnas.0503132102

PubMed ID: 16443825

Title: Identification of mouse palmitoyl-coenzyme A Delta9-desaturase.

PubMed ID: 16443825

DOI: 10.1194/jlr.c500025-jlr200

Sequence Information:

Length: 358
Mass: 40916
Checksum: 3E04893F12E92A9A
Sequence:

MPAHILQEIS GAYSATTTIT APPSGGQQNG GEKFEKSSHH WGADVRPELK DDLYDPTYQD 
DEGPPPKLEY VWRNIILMAL LHLGALYGIT LVPSCKLYTC LFAYLYYVIS ALGITAGAHR 
LWSHRTYKAR LPLRLFLIIA NTMAFQNDVY EWARDHRAHH KFSETHADPH NSRRGFFFSH 
VGWLLVRKHP AVKEKGGKLD MSDLKAEKLV MFQRRYYKPG LLLMCFVLPT LVPWYCWGET 
FVNSLCVSTF LRYAVVLNAT WLVNSAAHLY GYRPYDKNIS SRENILVSMG AVGEGFHNYH 
HAFPYDYSAS EYRWHINFTT FFIDCMALLG LAYDRKRVSR AAVLARIKRT GDGSCKSG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scd2

Associated with

Other Information

Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase. PubMed ID: 2570068

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse. PubMed ID: 10545940

Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin. PubMed ID: 11161812

Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. PubMed ID: 12815040

Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. PubMed ID: 16118274

Identification of mouse palmitoyl-coenzyme A Delta9-desaturase. PubMed ID: 16443825