Genular: Defining Cellular Identity and Function

Details for: Scg3

Gene ID: 20255

Symbol: Scg3

Ensembl ID: ENSMUSG00000032181

Description: secretogranin III

Associated with

Hemostasis
(R-MMU-109582)
Metabolism of proteins
(R-MMU-392499)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Post-translational protein modification
(R-MMU-597592)
Post-translational protein phosphorylation
(R-MMU-8957275)
Regulation of insulin-like growth factor (igf) transport and uptake by insulin-like growth factor binding proteins (igfbps)
(R-MMU-381426)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Cytoplasmic vesicle
(GO:0031410)
Extracellular region
(GO:0005576)
Membrane
(GO:0016020)
Protein binding
(GO:0005515)
Protein localization to secretory granule
(GO:0033366)
Secretory granule membrane
(GO:0030667)

Other Information

Proteins

Secretogranin-3

Genular Protein ID: 3368685164

Symbol: SCG3_MOUSE

Name: Secretogranin-3

UniProtKB Accession Codes:

P47867 Q3UTT1 Q3UZT8 Q8R1D7

Database IDs:

Citations:

PubMed ID: 7917832

Title: Primary structure of mouse secretogranin III and its absence from deficient mice.

PubMed ID: 7917832

DOI: 10.1007/bf02821554

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12388744

Title: Identification of a chromogranin A domain that mediates binding to secretogranin III and targeting to secretory granules in pituitary cells and pancreatic beta-cells.

PubMed ID: 12388744

DOI: 10.1091/mbc.02-03-0040

PubMed ID: 16219686

Title: Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules.

PubMed ID: 16219686

DOI: 10.1242/jcs.02608

PubMed ID: 17200173

Title: Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.

PubMed ID: 17200173

DOI: 10.1210/jc.2006-1808

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 28330905

Title: Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.

PubMed ID: 28330905

DOI: 10.1084/jem.20161802

Sequence Information:

Length: 471
Mass: 53326
Checksum: FC1E9C381AFCA564
Sequence:

MGFLWTGSWI LVLVLNSGPI QAFPKPEGSQ DKSLHNRELS AERPLNEQIA EAEADKIKKA 
FPSESKPSES NYSSVDNLNL LRAITEKETV EKERQSIRSP PFDNQLNVED ADSTKNRKLI 
DEYDSTKSGL DHKFQDDPDG LHQLDGTPLT AEDIVHKIAT RIYEENDRGV FDKIVSKLLN 
LGLITESQAH TLEDEVAEAL QKLISKEANN YEETLDKPTS RTENQDGKIP EKVTPVAAVQ 
DGFTNRENDE TVSNTLTLSN GLERRTNPHR EDDFEELQYF PNFYALLTSI DSEKEAKEKE 
TLITIMKTLI DFVKMMVKYG TISPEEGVSY LENLDETIAL QTKNKLEKNT TDSKSKLFPA 
PPEKSQEETD STKEEAAKME KEYGSLKDST KDDNSNLGGK TDEATGKTEA YLEAIRKNIE 
WLKKHNKKGN KEDYDLSKMR DFINQQADAY VEKGILDKEE ANAIKRIYSS L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scg3

Associated with

Other Information

Primary structure of mouse secretogranin III and its absence from deficient mice. PubMed ID: 7917832

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of a chromogranin A domain that mediates binding to secretogranin III and targeting to secretory granules in pituitary cells and pancreatic beta-cells. PubMed ID: 12388744

Interaction between secretogranin III and carboxypeptidase E facilitates prohormone sorting within secretory granules. PubMed ID: 16219686

Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity. PubMed ID: 17200173

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy. PubMed ID: 28330905