Genular: Defining Cellular Identity and Function

Details for: Scn1b

Gene ID: 20266

Symbol: Scn1b

Ensembl ID: ENSMUSG00000019194

Description: sodium channel, voltage-gated, type I, beta

Associated with

Axon guidance
(GO:0007411)
Cardiac conduction
(GO:0061337)
Cardiac muscle cell action potential involved in contraction
(GO:0086002)
Cardiac muscle contraction
(GO:0060048)
Cell projection
(GO:0042995)
Corticospinal neuron axon guidance
(GO:0021966)
Intercalated disc
(GO:0014704)
Locomotion
(GO:0040011)
Membrane
(GO:0016020)
Membrane depolarization
(GO:0051899)
Membrane depolarization during cardiac muscle cell action potential
(GO:0086012)
Membrane depolarization during purkinje myocyte cell action potential
(GO:0086047)
Monoatomic ion channel complex
(GO:0034702)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Neuronal action potential propagation
(GO:0019227)
Neuron projection development
(GO:0031175)
Node of ranvier
(GO:0033268)
Plasma membrane
(GO:0005886)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of sodium ion transport
(GO:0010765)
Positive regulation of voltage-gated sodium channel activity
(GO:1905152)
Protein binding
(GO:0005515)
Regulation of atrial cardiac muscle cell membrane depolarization
(GO:0060371)
Regulation of heart rate by cardiac conduction
(GO:0086091)
Regulation of sodium ion transmembrane transporter activity
(GO:2000649)
Regulation of sodium ion transport
(GO:0002028)
Regulation of ventricular cardiac muscle cell membrane repolarization
(GO:0060307)
Response to pyrethroid
(GO:0046684)
Sodium channel activity
(GO:0005272)
Sodium channel complex
(GO:0034706)
Sodium channel inhibitor activity
(GO:0019871)
Sodium channel regulator activity
(GO:0017080)
Sodium ion transmembrane transport
(GO:0035725)
Sodium ion transport
(GO:0006814)
T-tubule
(GO:0030315)
Transmembrane transporter binding
(GO:0044325)
Voltage-gated sodium channel activity
(GO:0005248)
Voltage-gated sodium channel activity involved in cardiac muscle cell action potential
(GO:0086006)
Voltage-gated sodium channel activity involved in purkinje myocyte action potential
(GO:0086062)
Voltage-gated sodium channel complex
(GO:0001518)

Other Information

Proteins

Sodium channel subunit beta-1

Genular Protein ID: 1331321913

Symbol: SCN1B_MOUSE

Name: Sodium channel subunit beta-1

UniProtKB Accession Codes:

P97952

Database IDs:

Citations:

PubMed ID: 9013777

Title: Sequence of the voltage-gated sodium channel beta1-subunit in wild-type and in quivering mice.

PubMed ID: 9013777

DOI: 10.1016/s0169-328x(96)00123-4

PubMed ID: 9721701

Title: Modulation of cardiac Na+ current phenotype by beta1-subunit expression.

PubMed ID: 9721701

DOI: 10.1161/01.res.83.4.441

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19710327

Title: A functional null mutation of SCN1B in a patient with Dravet syndrome.

PubMed ID: 19710327

DOI: 10.1523/jneurosci.2475-09.2009

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 218
Mass: 24650
Checksum: 5198F3383B0A8CA5
Sequence:

MGTLLALVVG AALVSSAWGG CVEVDSDTEA VYGMTFKILC ISCKRRSETT AETFTEWTFR 
QKGTEEFVKI LRYENEVLQL EEDERFEGRV VWNGSRGTKD LQDLSIFITN VTYNHSGDYE 
CHVYRLLFFD NYEHNTSVVK KIHLEVVDKA NRDMASIVSE IMMYVLIVVL TIWLVAEMVY 
CYKKIAAATE AAAQENASEY LAITSESKEN CTGVQVAE

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scn1b

Associated with

Other Information

Sequence of the voltage-gated sodium channel beta1-subunit in wild-type and in quivering mice. PubMed ID: 9013777

Modulation of cardiac Na+ current phenotype by beta1-subunit expression. PubMed ID: 9721701

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334