Genular: Defining Cellular Identity and Function

Details for: Scnn1g

Gene ID: 20278

Symbol: Scnn1g

Ensembl ID: ENSMUSG00000000216

Description: sodium channel, nonvoltage-gated 1 gamma

Associated with

Ion channel transport
(R-MMU-983712)
Sensory perception
(R-MMU-9709957)
Stimuli-sensing channels
(R-MMU-2672351)
Transport of small molecules
(R-MMU-382551)
Apical plasma membrane
(GO:0016324)
Cell surface
(GO:0009986)
Cellular response to acidic ph
(GO:0071468)
Cellular response to aldosterone
(GO:1904045)
Cellular response to vasopressin
(GO:1904117)
External side of plasma membrane
(GO:0009897)
Extracellular exosome
(GO:0070062)
Intracellular sodium ion homeostasis
(GO:0006883)
Ligand-gated sodium channel activity
(GO:0015280)
Membrane
(GO:0016020)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Monoatomic ion transport
(GO:0006811)
Multicellular organismal-level water homeostasis
(GO:0050891)
Nucleoplasm
(GO:0005654)
Plasma membrane
(GO:0005886)
Regulation of blood pressure
(GO:0008217)
Response to stimulus
(GO:0050896)
Sensory perception of salty taste
(GO:0050914)
Sensory perception of sour taste
(GO:0050915)
Sensory perception of taste
(GO:0050909)
Sodium channel activity
(GO:0005272)
Sodium channel complex
(GO:0034706)
Sodium ion homeostasis
(GO:0055078)
Sodium ion import across plasma membrane
(GO:0098719)
Sodium ion transmembrane transport
(GO:0035725)
Sodium ion transmembrane transporter activity
(GO:0015081)
Sodium ion transport
(GO:0006814)
Wound healing, spreading of epidermal cells
(GO:0035313)
Ww domain binding
(GO:0050699)

Other Information

Proteins

Amiloride-sensitive sodium channel subunit gamma

Genular Protein ID: 71932329

Symbol: SCNNG_MOUSE

Name: Amiloride-sensitive sodium channel subunit gamma

UniProtKB Accession Codes:

Q9WU39

Database IDs:

Citations:

PubMed ID: 10409305

Title: Cloning and functional expression of the mouse epithelial sodium channel.

PubMed ID: 10409305

DOI: 10.1152/ajprenal.1999.277.1.f121

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11244092

Title: The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel.

PubMed ID: 11244092

DOI: 10.1074/jbc.c000906200

PubMed ID: 12424229

Title: The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels.

PubMed ID: 12424229

DOI: 10.1096/fj.02-0497fje

PubMed ID: 15123669

Title: Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

PubMed ID: 15123669

DOI: 10.1074/jbc.m402820200

PubMed ID: 20525693

Title: Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.

PubMed ID: 20525693

DOI: 10.1074/jbc.m110.103432

Sequence Information:

Length: 655
Mass: 74635
Checksum: ABADDA9D6160596D
Sequence:

MAPGEKIKAK IKKNLPVRGP QAPTIKDLMH WYCLNTNTHG CRRIVVSRGR LRRLLWIAFT 
LTAVALIIWQ CALLVFSFYT VSVSIKVHFQ KLDFPAVTIC NINPYKYSAV SDLLTDLDSE 
TKQALLSLYG VKDVLDSTPR KRREAGSMRS TWEGTPPRFL NLIPLLVFNE NEKGKARDFF 
TGRKRKISGK IIHKASNVMH VHESKKLVGF QLCSNDTSDC ATYTFSSGIN AIQEWYKLHY 
MNIMAQVPLE KKINMSYSAE ELLVTCFFDG MSCDARNFTL FHHPMYGNCY TFNNRENATI 
LSTSMGGSEY GLQVILYINE DEYNPFLVSS TGAKVLVHQQ NEYPFIEDVG TEIETAMSTS 
IGMHLTESFK LSEPYSQCTE DGSDVPVTNI YNAAYSLQIC LYSCFQTKMV EKCGCAQYSQ 
PLPPAANYCN YQQHPNWMYC YYQLYQAFVR EELGCQSVCK QSCSFKEWTL TTSLAQWPSE 
ASEKWLLNVL TWDQSQQINK KLNKTDLAKL LIFYKDLNQR SIMESPANSI EMLLSNFGGQ 
LGLWMSCSVV CVIEIIEVFF IDFFSIIARR QWQKAKDWWA RRRTPPSTET PSSQQGQDNP 
ALDTDDDLPT FTSAMRLPPA PEAPVPGTPP PRYNTLRLDS AFSSQLTDTQ LTNEF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scnn1g

Associated with

Other Information

Cloning and functional expression of the mouse epithelial sodium channel. PubMed ID: 10409305

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel. PubMed ID: 11244092

The role of individual Nedd4-2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels. PubMed ID: 12424229

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. PubMed ID: 15123669