Genular: Defining Cellular Identity and Function

Details for: Scp2

Gene ID: 20280

Symbol: Scp2

Ensembl ID: ENSMUSG00000028603

Description: sterol carrier protein 2, liver

Associated with

Alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
(R-MMU-2046104)
Alpha-linolenic acid (ala) metabolism
(R-MMU-2046106)
Beta-oxidation of pristanoyl-coa
(R-MMU-389887)
Bile acid and bile salt metabolism
(R-MMU-194068)
Fatty acid metabolism
(R-MMU-8978868)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of steroids
(R-MMU-8957322)
Peroxisomal lipid metabolism
(R-MMU-390918)
Peroxisomal protein import
(R-MMU-9033241)
Protein localization
(R-MMU-9609507)
Synthesis of bile acids and bile salts
(R-MMU-192105)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
(R-MMU-193368)
Acetyl-coa c-acyltransferase activity
(GO:0003988)
Acetyl-coa c-myristoyltransferase activity
(GO:0050633)
Acyltransferase activity
(GO:0016746)
Acyltransferase activity, transferring groups other than amino-acyl groups
(GO:0016747)
Bile acid metabolic process
(GO:0008206)
Cholesterol binding
(GO:0015485)
Cholesterol transfer activity
(GO:0120020)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Fatty-acyl-coa binding
(GO:0000062)
Fatty acid beta-oxidation
(GO:0006635)
Identical protein binding
(GO:0042802)
Inositol trisphosphate biosynthetic process
(GO:0032959)
Intracellular cholesterol transport
(GO:0032367)
Lipid binding
(GO:0008289)
Lipid hydroperoxide transport
(GO:1901373)
Lipid metabolic process
(GO:0006629)
Lipid transport
(GO:0006869)
Long-chain fatty acyl-coa binding
(GO:0036042)
Mitochondrion
(GO:0005739)
Nucleoplasm
(GO:0005654)
Oleic acid binding
(GO:0070538)
Peroxisomal matrix
(GO:0005782)
Peroxisome
(GO:0005777)
Phosphatidylcholine transfer activity
(GO:0120019)
Phosphatidylethanolamine transfer activity
(GO:1904121)
Phosphatidylinositol transfer activity
(GO:0008526)
Phospholipid transport
(GO:0015914)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of cholesterol biosynthetic process
(GO:0045542)
Positive regulation of cholesterol import
(GO:1904109)
Positive regulation of intracellular cholesterol transport
(GO:0032385)
Positive regulation of steroid biosynthetic process
(GO:0010893)
Positive regulation of steroid metabolic process
(GO:0045940)
Progesterone biosynthetic process
(GO:0006701)
Propanoyl-coa c-acyltransferase activity
(GO:0033814)
Propionyl-coa c2-trimethyltridecanoyltransferase activity
(GO:0050632)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein localization to plasma membrane
(GO:0072659)
Regulation of phospholipid biosynthetic process
(GO:0071071)
Signaling receptor binding
(GO:0005102)
Steroid biosynthetic process
(GO:0006694)
Transferase activity
(GO:0016740)

Other Information

Proteins

Acetyl-CoA C-myristoyltransferase

Genular Protein ID: 3002857657

Symbol: SCP2_MOUSE

Name: Acetyl-CoA C-myristoyltransferase

UniProtKB Accession Codes:

P32020 A2APS2 A2APS3 Q9DBM7

Database IDs:

Citations:

PubMed ID: 8428655

Title: Cloning, expression and sequences of mouse sterol-carrier protein-x-encoding cDNAs and a related pseudogene.

PubMed ID: 8428655

DOI: 10.1016/0378-1119(93)90120-r

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1709640

Title: cDNA sequence and bacterial expression of mouse liver sterol carrier protein-2.

PubMed ID: 1709640

DOI: 10.1016/s0021-9258(18)92901-7

PubMed ID: 8751375

Title: Structure and chromosomal assignment of the murine sterol carrier protein 2 gene (Scp2) and two related pseudogenes by in situ hybridization.

PubMed ID: 8751375

DOI: 10.1159/000134355

PubMed ID: 9553048

Title: Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function.

PubMed ID: 9553048

DOI: 10.1101/gad.12.8.1189

PubMed ID: 11003606

Title: Sterol carrier protein-2 localization in endoplasmic reticulum and role in phospholipid formation.

PubMed ID: 11003606

DOI: 10.1152/ajpcell.2000.279.4.c1259

PubMed ID: 10706581

Title: Peroxisomal fatty acid oxidation disorders and 58 kDa sterol carrier protein X (SCPx). Activity measurements in liver and fibroblasts using a newly developed method.

PubMed ID: 10706581

PubMed ID: 16916647

Title: Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.

PubMed ID: 16916647

DOI: 10.1016/j.molcel.2006.06.026

PubMed ID: 17208939

Title: Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

PubMed ID: 17208939

DOI: 10.1074/mcp.m600218-mcp200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 26901662

Title: Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells.

PubMed ID: 26901662

DOI: 10.1371/journal.pone.0149728

Sequence Information:

Length: 547
Mass: 59126
Checksum: 37BA2E730D9CB105
Sequence:

MPSVALKSPR LRRVFVVGVG MTKFMKPGGE NSRDYPDMAK EAGQKALEDA QIPYSAVEQA 
CVGYVYGDST SGQRAIYHSL GLTGIPIINV NNNCSTGSTA LFMAHQLIQG GLANCVLALG 
FEKMERGSIG TKFSDRTTPT DKHIEVLIDK YGLSAHPITP QMFGYAGKEH MEKYGTKVEH 
FAKIGWKNHK HSVNNTYSQF QDEYSLEEVM KSKPVFDFLT ILQCCPTSDG AAAAILSSEE 
FVQQYGLQSK AVEIVAQEMM TDLPSTFEEK SIIKVVGYDM SKEAARRCYE KSGLTPNDVD 
VIELHDCFSV NELITYEALG LCPEGQGGTL VDRGDNTYGG KWVINPSGGL ISKGHPLGAT 
GLAQCAELCW QLRGEAGKRQ VPGAKVALQH NLGLGGAVVV TLYRMGFPEA ASSFRTHQVS 
AAPTSSAGDG FKANLVFKEI EKKLEEEGEQ FVKKIGGIFA FKVKDGPGGK EATWVVDVKN 
GKGSVLPNSD KKADCTITMA DSDLLALMTG KMNPQSAFFQ GKLKIAGNMG LAMKLQNLQL 
QPGKAKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Scp2

Associated with

Other Information

Cloning, expression and sequences of mouse sterol-carrier protein-x-encoding cDNAs and a related pseudogene. PubMed ID: 8428655

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

cDNA sequence and bacterial expression of mouse liver sterol carrier protein-2. PubMed ID: 1709640

Structure and chromosomal assignment of the murine sterol carrier protein 2 gene (Scp2) and two related pseudogenes by in situ hybridization. PubMed ID: 8751375

Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function. PubMed ID: 9553048

Sterol carrier protein-2 localization in endoplasmic reticulum and role in phospholipid formation. PubMed ID: 11003606

Peroxisomal fatty acid oxidation disorders and 58 kDa sterol carrier protein X (SCPx). Activity measurements in liver and fibroblasts using a newly developed method. PubMed ID: 10706581

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. PubMed ID: 16916647

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. PubMed ID: 17208939

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753

Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells. PubMed ID: 26901662