Genular: Defining Cellular Identity and Function

Details for: Scx

Gene ID: 20289

Symbol: Scx

Ensembl ID: ENSMUSG00000034161

Description: scleraxis scleraxis bHLH transcription factor

Associated with

Bhlh transcription factor binding
(GO:0043425)
Bmp signaling pathway
(GO:0030509)
Cartilage development
(GO:0051216)
Cell differentiation
(GO:0030154)
Cellular response to bmp stimulus
(GO:0071773)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Chondrocyte differentiation
(GO:0002062)
Cis-regulatory region sequence-specific dna binding
(GO:0000987)
Collagen fibril organization
(GO:0030199)
Deltoid tuberosity development
(GO:0035993)
Developmental process
(GO:0032502)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-templated transcription
(GO:0006351)
Dna binding
(GO:0003677)
E-box binding
(GO:0070888)
Embryonic skeletal system development
(GO:0048706)
Endochondral ossification
(GO:0001958)
Face morphogenesis
(GO:0060325)
Heart valve formation
(GO:0003188)
Heart valve morphogenesis
(GO:0003179)
Mesoderm formation
(GO:0001707)
Multicellular organism development
(GO:0007275)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dna-templated transcription
(GO:0045892)
Nucleus
(GO:0005634)
Positive regulation of cartilage development
(GO:0061036)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of collagen biosynthetic process
(GO:0032967)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of gastrulation
(GO:2000543)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein dimerization activity
(GO:0046983)
Regulation of cartilage development
(GO:0061035)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sclerotome development
(GO:0061056)
Sequence-specific dna binding
(GO:0043565)
Skeletal muscle cell differentiation
(GO:0035914)
Tendon cell differentiation
(GO:0035990)
Tendon development
(GO:0035989)
Tendon formation
(GO:0035992)
Tissue homeostasis
(GO:0001894)
Transcription regulator complex
(GO:0005667)

Other Information

Proteins

Basic helix-loop-helix transcription factor scleraxis

Genular Protein ID: 515452894

Symbol: SCX_MOUSE

Name: Basic helix-loop-helix transcription factor scleraxis

UniProtKB Accession Codes:

Q64124

Database IDs:

Citations:

PubMed ID: 7743923

Title: Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis.

PubMed ID: 7743923

DOI: 10.1242/dev.121.4.1099

PubMed ID: 10477299

Title: Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis.

PubMed ID: 10477299

DOI: 10.1242/dev.126.19.4317

Sequence Information:

Length: 207
Mass: 22239
Checksum: 8340052200A85EF9
Sequence:

MSFAMLRSAP PPGRYLYPEV SPLSEDEDRG SESSGSDEKP CRVHAARCGL QGARRRAGGR 
RAAGSGPGPG GRPGREPRQR HTANARERDR TNSVNTAFTA LRTLIPTEPA DRKLSKIETL 
RLASSYISHL GNVLLVGEAC GDGQPCHSGP AFFHSGRAGS PLPPPPPPPP LARDGGENTQ 
PKQICTFCLS NQRKLSKDRD RKTAIRS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.