Genular: Defining Cellular Identity and Function

Details for: Ccl11

Gene ID: 20292

Symbol: Ccl11

Ensembl ID: ENSMUSG00000020676

Description: C-C motif chemokine ligand 11

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Actin filament organization
(GO:0007015)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Branching involved in mammary gland duct morphogenesis
(GO:0060444)
Ccr3 chemokine receptor binding
(GO:0031728)
Ccr chemokine receptor binding
(GO:0048020)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to tumor necrosis factor
(GO:0071356)
Cellular response to type ii interferon
(GO:0071346)
Chemokine-mediated signaling pathway
(GO:0070098)
Chemokine activity
(GO:0008009)
Chemotaxis
(GO:0006935)
Cytokine activity
(GO:0005125)
Cytoskeleton organization
(GO:0007010)
Eosinophil chemotaxis
(GO:0048245)
Erk1 and erk2 cascade
(GO:0070371)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
G protein-coupled receptor signaling pathway
(GO:0007186)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Killing of cells of another organism
(GO:0031640)
Learning or memory
(GO:0007611)
Lymphocyte chemotaxis
(GO:0048247)
Mammary duct terminal end bud growth
(GO:0060763)
Mast cell chemotaxis
(GO:0002551)
Monocyte chemotaxis
(GO:0002548)
Negative regulation of neurogenesis
(GO:0050768)
Neutrophil chemotaxis
(GO:0030593)
Positive regulation of actin filament polymerization
(GO:0030838)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gtpase activity
(GO:0043547)
Protein dimerization activity
(GO:0046983)
Receptor ligand activity
(GO:0048018)
Regulation of cell shape
(GO:0008360)

Other Information

Proteins

Eotaxin

Genular Protein ID: 128312181

Symbol: CCL11_MOUSE

Name: Eotaxin

UniProtKB Accession Codes:

P48298

Database IDs:

Citations:

PubMed ID: 7568052

Title: Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression.

PubMed ID: 7568052

DOI: 10.1073/pnas.92.19.8960

PubMed ID: 8574847

Title: Mouse eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response.

PubMed ID: 8574847

DOI: 10.1016/s1074-7613(00)80293-9

PubMed ID: 10438970

Title: Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.

PubMed ID: 10438970

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9169149

Title: Genomic organization, complete sequence, and chromosomal location of the gene for human eotaxin (SCYA11), an eosinophil-specific CC chemokine.

PubMed ID: 9169149

DOI: 10.1006/geno.1997.4656

PubMed ID: 15647285

Title: Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation.

PubMed ID: 15647285

DOI: 10.1074/jbc.m406037200

Sequence Information:

Length: 97
Mass: 10893
Checksum: 36C9812107FC6CA7
Sequence:

MQSSTALLFL LLTVTSFTSQ VLAHPGSIPT SCCFIMTSKK IPNTLLKSYK RITNNRCTLK 
AIVFKTRLGK EICADPKKKW VQDATKHLDQ KLQTPKP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ccl11

Associated with

Other Information

Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression. PubMed ID: 7568052

Mouse eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response. PubMed ID: 8574847

Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis. PubMed ID: 10438970

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Genomic organization, complete sequence, and chromosomal location of the gene for human eotaxin (SCYA11), an eosinophil-specific CC chemokine. PubMed ID: 9169149

Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. PubMed ID: 15647285