Genular: Defining Cellular Identity and Function

Details for: Ccl12

Gene ID: 20293

Symbol: Ccl12

Ensembl ID: ENSMUSG00000035352

Description: C-C motif chemokine ligand 12

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Angiogenesis
(GO:0001525)
Ccr2 chemokine receptor binding
(GO:0031727)
Ccr chemokine receptor binding
(GO:0048020)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to tumor necrosis factor
(GO:0071356)
Cellular response to type ii interferon
(GO:0071346)
Chemokine-mediated signaling pathway
(GO:0070098)
Chemokine activity
(GO:0008009)
Chemotaxis
(GO:0006935)
Cytokine activity
(GO:0005125)
Eosinophil chemotaxis
(GO:0048245)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
G protein-coupled receptor signaling pathway
(GO:0007186)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Lymphocyte chemotaxis
(GO:0048247)
Monocyte chemotaxis
(GO:0002548)
Negative regulation of leukocyte proliferation
(GO:0070664)
Neutrophil chemotaxis
(GO:0030593)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gtpase activity
(GO:0043547)
Positive regulation of leukocyte migration
(GO:0002687)

Other Information

Proteins

C-C motif chemokine 12

Genular Protein ID: 4144369922

Symbol: CCL12_MOUSE

Name: C-C motif chemokine 12

UniProtKB Accession Codes:

Q62401 Q9QYD6

Database IDs:

Citations:

PubMed ID: 8920881

Title: Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammation.

PubMed ID: 8920881

DOI: 10.1084/jem.184.5.1939

PubMed ID: 8996246

Title: Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.

PubMed ID: 8996246

DOI: 10.1084/jem.185.1.99

PubMed ID: 10438970

Title: Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.

PubMed ID: 10438970

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 104
Mass: 11659
Checksum: 8D102F4FF4CC3DBF
Sequence:

MKISTLLCLL LIATTISPQV LAGPDAVSTP VTCCYNVVKQ KIHVRKLKSY RRITSSQCPR 
EAVIFRTILD KEICADPKEK WVKNSINHLD KTSQTFILEP SCLG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ccl12

Associated with

Other Information

Distinct expression and function of the novel mouse chemokine monocyte chemotactic protein-5 in lung allergic inflammation. PubMed ID: 8920881

Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1. PubMed ID: 8996246

Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis. PubMed ID: 10438970

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Database document:

PubMed ID: 8920881

PubMed ID: 8996246

PubMed ID: 10438970

PubMed ID: 15489334