Genular: Defining Cellular Identity and Function

Details for: Ccl4

Gene ID: 20303

Symbol: Ccl4

Ensembl ID: ENSMUSG00000018930

Description: C-C motif chemokine ligand 4

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Ccr1 chemokine receptor binding
(GO:0031726)
Ccr5 chemokine receptor binding
(GO:0031730)
Ccr chemokine receptor binding
(GO:0048020)
Cellular response to interleukin-1
(GO:0071347)
Cellular response to tumor necrosis factor
(GO:0071356)
Cellular response to type ii interferon
(GO:0071346)
Cellular response to xenobiotic stimulus
(GO:0071466)
Chemokine-mediated signaling pathway
(GO:0070098)
Chemokine activity
(GO:0008009)
Chemotaxis
(GO:0006935)
Cytokine activity
(GO:0005125)
Eosinophil chemotaxis
(GO:0048245)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
G protein-coupled receptor signaling pathway
(GO:0007186)
Identical protein binding
(GO:0042802)
Immune response
(GO:0006955)
Inflammatory response
(GO:0006954)
Leukocyte chemotaxis
(GO:0030595)
Lymphocyte chemotaxis
(GO:0048247)
Monocyte chemotaxis
(GO:0002548)
Neutrophil chemotaxis
(GO:0030593)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gtpase activity
(GO:0043547)
Positive regulation of tumor necrosis factor production
(GO:0032760)
Positive regulation of vascular permeability
(GO:0043117)
Protein binding
(GO:0005515)

Other Information

Proteins

C-C motif chemokine 4

Genular Protein ID: 985448003

Symbol: CCL4_MOUSE

Name: C-C motif chemokine 4

UniProtKB Accession Codes:

P14097

Database IDs:

Citations:

PubMed ID: 3058856

Title: Resolution of the two components of macrophage inflammatory protein 1, and cloning and characterization of one of those components, macrophage inflammatory protein 1 beta.

PubMed ID: 3058856

DOI: 10.1084/jem.168.6.2251

PubMed ID: 2521353

Title: A family of small inducible proteins secreted by leukocytes are members of a new superfamily that includes leukocyte and fibroblast-derived inflammatory agents, growth factors, and indicators of various activation processes.

PubMed ID: 2521353

PubMed ID: 10438970

Title: Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.

PubMed ID: 10438970

Sequence Information:

Length: 92
Mass: 10168
Checksum: 8853FD58FDE61BAC
Sequence:

MKLCVSALSL LLLVAAFCAP GFSAPMGSDP PTSCCFSYTS RQLHRSFVMD YYETSSLCSK 
PAVVFLTKRG RQICANPSEP WVTEYMSDLE LN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.