Genular: Defining Cellular Identity and Function

Details for: Cxcl12

Gene ID: 20315

Symbol: Cxcl12

Ensembl ID: ENSMUSG00000061353

Description: C-X-C motif chemokine ligand 12

Associated with

Chemokine receptors bind chemokines
(R-MMU-380108)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
Developmental biology
(R-MMU-1266738)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Nervous system development
(R-MMU-9675108)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signaling by robo receptors
(R-MMU-376176)
Signal transduction
(R-MMU-162582)
Adult locomotory behavior
(GO:0008344)
Animal organ regeneration
(GO:0031100)
Antimicrobial humoral immune response mediated by antimicrobial peptide
(GO:0061844)
Axon guidance
(GO:0007411)
Blood vessel endothelial cell migration
(GO:0043534)
Brain development
(GO:0007420)
Branching involved in blood vessel morphogenesis
(GO:0001569)
Cell-cell adhesion
(GO:0098609)
Cell chemotaxis
(GO:0060326)
Cellular response to chemokine
(GO:1990869)
Chemokine (c-x-c motif) ligand 12 signaling pathway
(GO:0038146)
Chemokine-mediated signaling pathway
(GO:0070098)
Chemokine activity
(GO:0008009)
Chemokine receptor binding
(GO:0042379)
Chemotaxis
(GO:0006935)
Cxcl12-activated cxcr4 signaling pathway
(GO:0038160)
Cxcr chemokine receptor binding
(GO:0045236)
Cytokine activity
(GO:0005125)
Defense response
(GO:0006952)
Detection of mechanical stimulus involved in sensory perception of pain
(GO:0050966)
Detection of temperature stimulus involved in sensory perception of pain
(GO:0050965)
Dopaminergic neuron differentiation
(GO:0071542)
External side of plasma membrane
(GO:0009897)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Germ cell development
(GO:0007281)
Germ cell migration
(GO:0008354)
Growth factor activity
(GO:0008083)
Immune response
(GO:0006955)
Induction of positive chemotaxis
(GO:0050930)
Integrin activation
(GO:0033622)
Integrin binding
(GO:0005178)
Killing of cells of another organism
(GO:0031640)
Motor neuron axon guidance
(GO:0008045)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of dendritic cell apoptotic process
(GO:2000669)
Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage
(GO:1902230)
Negative regulation of leukocyte tethering or rolling
(GO:1903237)
Neuron migration
(GO:0001764)
Positive regulation of axon extension involved in axon guidance
(GO:0048842)
Positive regulation of calcium ion import
(GO:0090280)
Positive regulation of cell adhesion
(GO:0045785)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of chemotaxis
(GO:0050921)
Positive regulation of dopamine secretion
(GO:0033603)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of monocyte chemotaxis
(GO:0090026)
Positive regulation of myoblast fusion
(GO:1901741)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of t cell migration
(GO:2000406)
Positive regulation of vasculature development
(GO:1904018)
Regulation of calcium ion transport
(GO:0051924)
Regulation of cell migration
(GO:0030334)
T cell chemotaxis
(GO:0010818)
T cell proliferation
(GO:0042098)
Telencephalon cell migration
(GO:0022029)

Other Information

Proteins

Stromal cell-derived factor 1
H7BX38_MOUSE

Genular Protein ID: 197862193

Symbol: SDF1_MOUSE

Name: Stromal cell-derived factor 1

UniProtKB Accession Codes:

P40224 Q4FJL5 Q543V6

Database IDs:

Citations:

PubMed ID: 8342023

Title: Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins.

PubMed ID: 8342023

DOI: 10.1126/science.8342023

PubMed ID: 7982471

Title: Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA).

PubMed ID: 7982471

DOI: 10.1006/excr.1994.1344

PubMed ID: 8134392

Title: Molecular cloning and structure of a pre-B-cell growth-stimulating factor.

PubMed ID: 8134392

DOI: 10.1073/pnas.91.6.2305

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8757135

Title: Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1.

PubMed ID: 8757135

DOI: 10.1038/382635a0

Sequence Information:

Length: 93
Mass: 10561
Checksum: 625367D344B8AD69
Sequence:

MDAKVVAVLA LVLAALCISD GKPVSLSYRC PCRFFESHIA RANVKHLKIL NTPNCALQIV 
ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR LKM

Genular Protein ID: 937156391

Symbol: H7BX38_MOUSE

Name: N/A

UniProtKB Accession Codes:

H7BX38

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Title: Deciphering the structural attributes of protein-heparan sulfate interactions using chemo-enzymatic approaches and NMR spectroscopy.

DOI: 10.1093/glycob/cwab012

Sequence Information:

Length: 119
Mass: 13634
Checksum: E87A2F139C651B2E
Sequence:

MDAKVVAVLA LVLAALCISD GKPVSLSYRC PCRFFESHIA RANVKHLKIL NTPNCALQIV 
ARLKNNNRQV CIDPKLKWIQ EYLEKALNKG RREEKVGKKE KIGKKKRQKK RKAAQKRKN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Cxcl12

Associated with

Other Information

Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. PubMed ID: 8342023

Molecular cloning of TPAR1, a gene whose expression is repressed by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA). PubMed ID: 7982471

Molecular cloning and structure of a pre-B-cell growth-stimulating factor. PubMed ID: 8134392

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. PubMed ID: 8757135

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Deciphering the structural attributes of protein-heparan sulfate interactions using chemo-enzymatic approaches and NMR spectroscopy.