Genular: Defining Cellular Identity and Function

Details for: Nptn

Gene ID: 20320

Symbol: Nptn

Ensembl ID: ENSMUSG00000032336

Description: neuroplastin

Associated with

Axon guidance
(GO:0007411)
Cell adhesion
(GO:0007155)
Cell adhesion molecule binding
(GO:0050839)
Cell surface
(GO:0009986)
Dendrite
(GO:0030425)
Excitatory synapse assembly
(GO:1904861)
Gaba-ergic synapse
(GO:0098982)
Glutamatergic synapse
(GO:0098978)
Homophilic cell adhesion via plasma membrane adhesion molecules
(GO:0007156)
Immunological synapse
(GO:0001772)
Inhibitory synapse
(GO:0060077)
Intracellular calcium ion homeostasis
(GO:0006874)
Long-term synaptic potentiation
(GO:0060291)
Membrane
(GO:0016020)
Modulation of chemical synaptic transmission
(GO:0050804)
Negative regulation of cytokine production
(GO:0001818)
Nervous system development
(GO:0007399)
Plasma membrane
(GO:0005886)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of fibroblast growth factor receptor signaling pathway
(GO:0045743)
Positive regulation of long-term neuronal synaptic plasticity
(GO:0048170)
Positive regulation of long-term synaptic potentiation
(GO:1900273)
Positive regulation of neuron projection development
(GO:0010976)
Positive regulation of protein localization
(GO:1903829)
Positive regulation of protein phosphorylation
(GO:0001934)
Postsynaptic density membrane
(GO:0098839)
Presynaptic active zone membrane
(GO:0048787)
Presynaptic membrane
(GO:0042734)
Protein binding
(GO:0005515)
Regulation of receptor localization to synapse
(GO:1902683)
Schaffer collateral - ca1 synapse
(GO:0098685)
Synapse
(GO:0045202)
Synapse organization
(GO:0050808)
Synaptic membrane
(GO:0097060)
Trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
(GO:0099557)
Transmembrane transporter binding
(GO:0044325)
Type 1 fibroblast growth factor receptor binding
(GO:0005105)
Visual learning
(GO:0008542)

Other Information

Proteins

Neuroplastin

Genular Protein ID: 1951953422

Symbol: NPTN_MOUSE

Name: Neuroplastin

UniProtKB Accession Codes:

P97300 Q3U519 Q8C637 Q8C6H8

Database IDs:

Citations:

PubMed ID: 8938438

Title: Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method.

PubMed ID: 8938438

DOI: 10.1006/geno.1996.0560

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 16944957

Title: Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PubMed ID: 16944957

DOI: 10.1021/pr060186m

PubMed ID: 19656770

Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.

PubMed ID: 19656770

DOI: 10.1074/mcp.m900195-mcp200

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 28827723

Title: A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.

PubMed ID: 28827723

DOI: 10.1038/s41598-017-08519-4

Sequence Information:

Length: 397
Mass: 44373
Checksum: E9C19EE0BD3A324A
Sequence:

MSGSSLPGAL ALSLLLVSGS LLPGPGAAQN AGFVKSPMSE TKLTGDAFEL YCDVVGSPTP 
EIQWWYAEVN RAESFRQLWD GARKRRVTVN TAYGSNGVSV LRITRLTLED SGTYECRASN 
DPKRNDLRQN PSITWIRAQA TISVLQKPRI VTSEEVIIRE SLLPVTLQCN LTSSSHTLMY 
SYWTRNGVEL TATRKNASNM EYRINKPRAE DSGEYHCVYH FVSAPKANAT IEVKAAPDIT 
GHKRSENKNE GQDAMMYCKS VGYPHPEWIW RKKENGVFEE ISNSSGRFFI TNKENYTELS 
IVNLQITEDP GEYECNATNS IGSASVSTVL RVRSHLAPLW PFLGILAEII ILVVIIVVYE 
KRKRPDEVPD DDEPAGPMKT NSTNNHKDKN LRQRNTN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nptn

Associated with

Other Information

Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. PubMed ID: 8938438

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Proteome-wide characterization of N-glycosylation events by diagonal chromatography. PubMed ID: 16944957

The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. PubMed ID: 19656770

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation. PubMed ID: 28827723