Genular: Defining Cellular Identity and Function

Details for: Sec23a

Gene ID: 20334

Symbol: Sec23a

Ensembl ID: ENSMUSG00000020986

Description: SEC23 homolog A, COPII coat complex component

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen presentation: folding, assembly and peptide loading of class i mhc
(R-MMU-983170)
Asparagine n-linked glycosylation
(R-MMU-446203)
Cargo concentration in the er
(R-MMU-5694530)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Copii-mediated vesicle transport
(R-MMU-204005)
Er to golgi anterograde transport
(R-MMU-199977)
Immune system
(R-MMU-168256)
Membrane trafficking
(R-MMU-199991)
Metabolism of proteins
(R-MMU-392499)
Mhc class ii antigen presentation
(R-MMU-2132295)
Post-translational protein modification
(R-MMU-597592)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Copii-coated er to golgi transport vesicle
(GO:0030134)
Copii-coated vesicle budding
(GO:0090114)
Copii-coated vesicle cargo loading
(GO:0090110)
Copii vesicle coat
(GO:0030127)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum exit site
(GO:0070971)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum to golgi vesicle-mediated transport
(GO:0006888)
Er to golgi transport vesicle membrane
(GO:0012507)
Golgi membrane
(GO:0000139)
Gtpase activator activity
(GO:0005096)
Intracellular protein transport
(GO:0006886)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Perinuclear region of cytoplasm
(GO:0048471)
Protein binding
(GO:0005515)
Protein localization to plasma membrane
(GO:0072659)
Protein transport
(GO:0015031)
Vesicle-mediated transport
(GO:0016192)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

SEC23-related protein A
Q8C1E4_MOUSE

Genular Protein ID: 1940806108

Symbol: SC23A_MOUSE

Name: SEC23-related protein A

UniProtKB Accession Codes:

Q01405 Q8JZL4

Database IDs:

Citations:

PubMed ID: 12193656

Title: Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER.

PubMed ID: 12193656

DOI: 10.1073/pnas.182412799

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8417978

Title: Identification and differential expression of yeast SEC23-related gene (Msec23) in mouse tissues.

PubMed ID: 8417978

DOI: 10.1016/0014-5793(93)81161-r

PubMed ID: 10400679

Title: p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins.

PubMed ID: 10400679

DOI: 10.1074/jbc.274.29.20505

PubMed ID: 15466885

Title: New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting.

PubMed ID: 15466885

DOI: 10.1242/jcs.01379

PubMed ID: 17428803

Title: Mammalian Sec16/p250 plays a role in membrane traffic from the endoplasmic reticulum.

PubMed ID: 17428803

DOI: 10.1074/jbc.m611237200

PubMed ID: 17452640

Title: Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity.

PubMed ID: 17452640

DOI: 10.1073/pnas.0610964104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27354378

Title: SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes.

PubMed ID: 27354378

DOI: 10.1083/jcb.201509052

Sequence Information:

Length: 765
Mass: 86162
Checksum: C0FD4C2C1578B6A5
Sequence:

MTTYLEFIQQ NEERDGVRFS WNVWPSSRLE ATRMVVPVAA LFTPLKERPD LPPIQYEPVL 
CSRTTCRAVL NPLCQVDYRA KLWACNFCYQ RNQFPPTYAG ISELNQPAEL LPQFSSIEYV 
VLRGPQMPLI FLYVVDTCIE DEDLQALKES MQMSLSLLPP TALVGLITFG RMVQVHELGC 
EGISKSYVFR GTKDLSAKQL QEMLGLSKVP VTQATRGPQV QQPPPSNRFL QPVQKIDMNL 
TDLLGELQRD PWPVPQGKRP LRSSGVALSI AVGLLECTFP NTGARIMMFI GGPATQGPGM 
VVGDELKTPI RSWHDIEKDN AKYVKKGTKH FEALANRAAT TGHVIDIYAC ALDQTGLLEM 
KCCPNLTGGY MVMGDSFNTS LFKQTFQRVF TKDIHGQFKM GFGGTLEIKT SREIKISGAI 
GPCVSLNSKG PCVSENEIGT GGTCQWKICG LSPTTTLAIY FEVVNQHNAP IPQGGRGAVQ 
FVTQYQHSSG QRRIRVTTIA RNWADAQTQI QNIAASFDQE AAAILMARLA IYRAETEEGP 
DVLRWLDRQL IRLCQKFGEY HKDDPNSFRF SETFSLYPQF MFHLRRSPFL QVFNNSPDES 
SYYRHHFMRQ DLTQSLIMIQ PILYAYSFSG PPEPVLLDSS SILADRILLM DTFFQILIYH 
GETIAQWRKS GYQDMPEYEN FRHLLQAPVD DAQEILHSRF PMPRYIDTEH GGSQARFLLS 
KVNPSQTHNN MYAWGQESGA PILTDDVSLQ VFMDHLKKLA VSSAA

Genular Protein ID: 3641725754

Symbol: Q8C1E4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8C1E4

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 765
Mass: 86089
Checksum: E7CB688415BBA644
Sequence:

MTTYLEFIQQ NEKRDGVRFS WNVWPSSRLE ATRMVVPVAA LFTPLKERPD LPPIQYEPVL 
CSRTTCRAVL NPLCQVDYRA KLWACNFCYQ RNQFPPTYAG ISELNQPAEL LPQFSSIEYV 
VLRGPQMPLI FLYVVDTCIE DEDLQALKES MQMSLSLLPP TALVGLITFG RMVQVHELGC 
EGISKSYVFR GTKDLSAKQL QEMLGLSKVP VTQATRGPQV QQPPPSNRFL QPVQKIDMNL 
TDLLGELQRD PWPVPQGKRP LRSSGVALSI AVGLLECTFP NTGARIMMFI GGPATQGPGM 
VVGDELKTPI RSWHDIEKDN AKYVKKGTKH FEALANRAAT TGHVIDIYAC ALDQTGLLEM 
KCCPNLTGGY MVMGDSFNTS LFKQTFQRVF TKDIHGQFKM GFGGTLEIKT SREIKISGAI 
GPCVSLNSKG PCVSENGIGT GGTCQWKICG LSPTTTLAIY FEVVNQHNAP IPQGGRGAVQ 
FVTQYQHSSG QRRIRVTTIA RNWADAQTQI QNIAASFDQE AAAILMARLA IYRAETEEGP 
DVLRWLDRQL IRLCQKFGEY HKDDPNSFRF SETFSLYPQF MFHLRRSPFL QVFNNSPDES 
SYYRHHFMRQ DLTQSLIMIQ PILYAYSFSG PPEPVLLDSS SILADRILLM DTFFQILIYH 
GETIAQWRKS GYQDMPEYEN FRHLLQAPVD DAQEILHSRF PMPRYIDTEH GGSQARFLLS 
KVNPSQTHNN MYAWGQESGA PILTDDVSLQ VFMDHLKKLA VSSAA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sec23a

Associated with

Other Information

Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER. PubMed ID: 12193656

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification and differential expression of yeast SEC23-related gene (Msec23) in mouse tissues. PubMed ID: 8417978

p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins. PubMed ID: 10400679

New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. PubMed ID: 15466885

Mammalian Sec16/p250 plays a role in membrane traffic from the endoplasmic reticulum. PubMed ID: 17428803

Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity. PubMed ID: 17452640

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes. PubMed ID: 27354378

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073