Genular: Defining Cellular Identity and Function

Details for: Selp

Gene ID: 20344

Symbol: Selp

Ensembl ID: ENSMUSG00000026580

Description: selectin, platelet

Associated with

Cell surface interactions at the vascular wall
(R-MMU-202733)
Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
(GO:0016339)
Calcium-dependent protein binding
(GO:0048306)
Calcium-mediated signaling using intracellular calcium source
(GO:0035584)
Calcium ion binding
(GO:0005509)
Carbohydrate binding
(GO:0030246)
Cell-cell adhesion
(GO:0098609)
Cell adhesion
(GO:0007155)
Cellular response to interleukin-6
(GO:0071354)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Fucose binding
(GO:0042806)
Heparin binding
(GO:0008201)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
(GO:0007157)
Inflammatory response
(GO:0006954)
Leukocyte cell-cell adhesion
(GO:0007159)
Leukocyte migration
(GO:0050900)
Leukocyte tethering or rolling
(GO:0050901)
Lipopolysaccharide binding
(GO:0001530)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Oligosaccharide binding
(GO:0070492)
Plasma membrane
(GO:0005886)
Platelet alpha granule membrane
(GO:0031092)
Positive regulation of cell adhesion
(GO:0045785)
Positive regulation of leukocyte migration
(GO:0002687)
Positive regulation of leukocyte tethering or rolling
(GO:1903238)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of platelet activation
(GO:0010572)
Protein binding
(GO:0005515)
Regulation of cellular extravasation
(GO:0002691)
Regulation of integrin activation
(GO:0033623)
Response to cytokine
(GO:0034097)
Sialic acid binding
(GO:0033691)

Other Information

Proteins

P-selectin

Genular Protein ID: 209960553

Symbol: LYAM3_MOUSE

Name: P-selectin

UniProtKB Accession Codes:

Q01102 Q32MF1

Database IDs:

Citations:

PubMed ID: 1378846

Title: Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.

PubMed ID: 1378846

DOI: 10.1016/s0021-9258(18)42162-x

PubMed ID: 1379089

Title: Molecular cloning and analysis of in vivo expression of murine P-selectin.

PubMed ID: 1379089

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12370362

Title: P-, E-, and L-selectin mediate migration of activated CD8+ T lymphocytes into inflamed skin.

PubMed ID: 12370362

DOI: 10.4049/jimmunol.169.8.4307

PubMed ID: 12393631

Title: N-terminal residues in murine P-selectin glycoprotein ligand-1 required for binding to murine P-selectin.

PubMed ID: 12393631

DOI: 10.1182/blood-2001-11-0036

Sequence Information:

Length: 768
Mass: 83099
Checksum: E5173074D2F66E68
Sequence:

MAGCPKGSWT PRLRSVILGG AQLIWFSALI SELVNQKEVA AWTYNYSTKA YSWNNSRVFC 
RRHFTDLVAI QNKNEIAHLN DVIPFFNSYY WIGIRKINNK WTWVGTNKTL TEEAENWADN 
EPNNKKNNQD CVEIYIKSNS APGKWNDEPC FKRKRALCYT ASCQDMSCSN QGECIETIGS 
YTCSCYPGFY GPECEYVKEC GKVNIPQHVL MNCSHPLGEF SFNSQCTFSC AEGYELDGPG 
ELQCLASGIW TNNPPKCDAV QCQSLEAPPH GTMACMHPIA AFAYDSSCKF ECQPGYRARG 
SNTLHCTGSG QWSEPLPTCE AIACEPPEIP IHGSMDCVPS TGTFGYNSSC TFLCAEGFVL 
KGNDAIQCAD SGQWTAPAPF CEALQCPEFP VPSKAQVNCS DPFGTLTYQS VCSFSCDEGS 
LLVGASVIRC LATGHWNGAP PECQAVSCAP MLSPENGSMT CVQPLGNSTY KSTCQFMCDE 
GFYLSGPERL DCSPSGHWTG TPPTCEAIKC PGIFAPEQGN LDCSHVHGEF GVGSICHFSC 
NEDFELLGSE NVECTVSGRW SAPPPTCKGI TSLPAPAVRC PALTTPGQGT MSCQHHLGSF 
GPNTTCYFGC KTGFTLRGAN SLRCRASGQW TAVTPMCRAV KCSELHMDTA VAMNCSNPWG 
NFSYGSTCTF QCPEGQSLNG SVRATCREDG HWSDAMPTCQ AGTLTIQEAL TYLGGAVAST 
TGLAVGGTLL ALLRKRLRKK DDGKCPLNPH SHLGTYGVFT NAAYDPTP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Selp

Associated with

Other Information

Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha. PubMed ID: 1378846

Molecular cloning and analysis of in vivo expression of murine P-selectin. PubMed ID: 1379089

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334