Genular: Defining Cellular Identity and Function

Details for: Sema3c

Gene ID: 20348

Symbol: Sema3c

Ensembl ID: ENSMUSG00000028780

Description: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

Associated with

Axon guidance
(GO:0007411)
Blood vessel remodeling
(GO:0001974)
Cardiac endothelial to mesenchymal transition
(GO:0140074)
Cardiac right ventricle morphogenesis
(GO:0003215)
Cell differentiation
(GO:0030154)
Chemorepellent activity
(GO:0045499)
Collagen-containing extracellular matrix
(GO:0062023)
Dichotomous subdivision of terminal units involved in salivary gland branching
(GO:0060666)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Heart development
(GO:0007507)
Limb bud formation
(GO:0060174)
Multicellular organism development
(GO:0007275)
Negative chemotaxis
(GO:0050919)
Negative regulation of axon extension involved in axon guidance
(GO:0048843)
Nervous system development
(GO:0007399)
Neural crest cell migration
(GO:0001755)
Neural tube development
(GO:0021915)
Outflow tract morphogenesis
(GO:0003151)
Outflow tract septum morphogenesis
(GO:0003148)
Plasma membrane
(GO:0005886)
Positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
(GO:1905312)
Positive regulation of cell migration
(GO:0030335)
Post-embryonic development
(GO:0009791)
Pulmonary myocardium development
(GO:0003350)
Semaphorin-plexin signaling pathway
(GO:0071526)
Semaphorin receptor binding
(GO:0030215)
Somitogenesis
(GO:0001756)

Other Information

Proteins

Semaphorin-3C

Genular Protein ID: 2339920637

Symbol: SEM3C_MOUSE

Name: Semaphorin-3C

UniProtKB Accession Codes:

Q62181 Q6NXW7

Database IDs:

Citations:

PubMed ID: 7748561

Title: Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension.

PubMed ID: 7748561

DOI: 10.1016/0896-6273(95)90332-1

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11688556

Title: Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption.

PubMed ID: 11688556

DOI: 10.1242/dev.128.16.3061

PubMed ID: 15239958

Title: PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development.

PubMed ID: 15239958

DOI: 10.1016/j.devcel.2004.06.002

PubMed ID: 17021275

Title: Functional interaction between matrix metalloproteinase-3 and semaphorin-3C during cortical axonal growth and guidance.

PubMed ID: 17021275

DOI: 10.1093/cercor/bhl082

Sequence Information:

Length: 751
Mass: 85289
Checksum: 32537E9D664123EE
Sequence:

MAFRAICVLV GVFICSICVR GSSQPQARVY LTFDELRETK TSEYFSLSHQ QLDYRILLMD 
EDQDRIYVGS KDHILSLNIN NISQEPLSVF WPASTIKVEE CKMAGKDPTH GCGNFVRVIQ 
TFNRTHLYVC GSGAFSPVCT YLNRGRRSED QVFMIDSKCE SGKGRCSFNP NVNTVSVMIN 
EELFSGMYID FMGTDAAIFR SLTKRNAVRT DQHNSKWLSE PMFVDAHVIP DGTDPNDAKV 
YFFFKERLTD NNRSTKQIHS MIARICPNDT GGQRSLVNKW TTFLKARLVC SVTDEDGPET 
HFDELEDVFL LETDNPRTTL VYGIFTTSSS VFKGSAVCVY HLSDIQTVFN GPFAHKEGPN 
HQLISYQGRI PYPRPGTCPG GAFTPNMRTT KDFPDDVVTF IRNHPLMYNS IYPIHRRPLI 
VRIGTDYKYT KIAVDRVNAA DGRYHVLFLG TDRGTVQKVV VLPTNSSASG ELILEELEVF 
KNHVPITTMK ISSKKQQLYV SSNEGVSQVS LHRCHIYGTA CADCCLARDP YCAWDGHSCS 
RFYPTGKRRS RRQDVRHGNP LTQCRGFNLK AYRNAAEIVQ YGVRNNSTFL ECAPKSPQAS 
IKWLLQKDKD RRKEVKLNER IIATSQGLLI RSVQDSDQGL YHCIATENSF KQTIAKINFK 
VLDSEMVAVV TDKWSPWTWA GSVRALPFHP KDILGAFSHS EMQLINQYCK DTRQQQQLGE 
EPQKMRGDYG KLKALINSRK SRNRRNQLPE S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sema3c

Associated with

Other Information

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. PubMed ID: 7748561

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. PubMed ID: 11688556