Details for: Sgk1

Gene ID: 20393

Symbol: Sgk1

Ensembl ID: ENSMUSG00000019970

Description: serum/glucocorticoid regulated kinase 1

Associated with

Other Information

Genular Protein ID: 1153457787

Symbol: SGK1_MOUSE

Name: Serine/threonine-protein kinase Sgk1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10358046

Title: sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial Na+ channels.

PubMed ID: 10358046

DOI: 10.1074/jbc.274.24.16973

PubMed ID: 10751222

Title: Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel.

PubMed ID: 10751222

DOI: 10.1152/ajprenal.2000.278.4.f613

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8647846

Title: p53 stimulates promoter activity of the sgk. serum/glucocorticoid-inducible serine/threonine protein kinase gene in rodent mammary epithelial cells.

PubMed ID: 8647846

DOI: 10.1074/jbc.271.21.12414

PubMed ID: 12488318

Title: Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells.

PubMed ID: 12488318

DOI: 10.1074/jbc.m211649200

PubMed ID: 12684516

Title: Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A.

PubMed ID: 12684516

DOI: 10.1074/jbc.m212301200

PubMed ID: 15774535

Title: Glucocorticoid adrenal steroids and glucocorticoid-inducible kinase isoforms in the regulation of GluR6 expression.

PubMed ID: 15774535

DOI: 10.1113/jphysiol.2004.079624

PubMed ID: 19756449

Title: Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

PubMed ID: 19756449

DOI: 10.1007/s00109-009-0525-5

PubMed ID: 20568246

Title: Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis.

PubMed ID: 20568246

DOI: 10.1002/dvdy.22345

PubMed ID: 20525693

Title: Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.

PubMed ID: 20525693

DOI: 10.1074/jbc.m110.103432

PubMed ID: 19965929

Title: Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1.

PubMed ID: 19965929

DOI: 10.1210/me.2009-0265

PubMed ID: 21385992

Title: Stimulation of Ca2+-channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1).

PubMed ID: 21385992

DOI: 10.1096/fj.10-178210

PubMed ID: 21757730

Title: mSIN1 protein mediates SGK1 protein interaction with mTORC2 protein complex and is required for selective activation of the epithelial sodium channel.

PubMed ID: 21757730

DOI: 10.1074/jbc.m111.257592

PubMed ID: 21147854

Title: Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.

PubMed ID: 21147854

DOI: 10.1242/jcs.073924

PubMed ID: 21865597

Title: Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.

PubMed ID: 21865597

DOI: 10.1091/mbc.e11-04-0328

Sequence Information:

  • Length: 431
  • Mass: 48928
  • Checksum: 6DF5B8464A4C2754
  • Sequence:
  • MTVKAEAARS TLTYSRMRGM VAILIAFMKQ RRMGLNDFIQ KIASNTYACK HAEVQSILKM 
    SHPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE 
    EVFYAVKVLQ KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHFSFQTAD KLYFVLDYIN 
    GGELFYHLQR ERCFLEPRAR FYAAEIASAL GYLHSLNIVY RDLKPENILL DSQGHIVLTD 
    FGLCKENIEH NGTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR 
    NTAEMYDNIL NKPLQLKPNI TNSARHLLEG LLQKDRTKRL GAKDDFMEIK SHIFFSLINW 
    DDLINKKITP PFNPNVSGPS DLRHFDPEFT EEPVPSSIGR SPDSILVTAS VKEAAEAFLG 
    FSYAPPVDSF L

Genular Protein ID: 3410832934

Symbol: E9Q1B0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 417
  • Mass: 47563
  • Checksum: 0D1843E7C5FDB55A
  • Sequence:
  • MKEETLRSPW KAFMKQRRMG LNDFIQKIAS NTYACKHAEV QSILKMSHPQ EPELMNANPS 
    PPPSPSQQIN LGPSSNPHAK PSDFHFLKVI GKGSFGKVLL ARHKAEEVFY AVKVLQKKAI 
    LKKKEEKHIM SERNVLLKNV KHPFLVGLHF SFQTADKLYF VLDYINGGEL FYHLQRERCF 
    LEPRARFYAA EIASALGYLH SLNIVYRDLK PENILLDSQG HIVLTDFGLC KENIEHNGTT 
    STFCGTPEYL APEVLHKQPY DRTVDWWCLG AVLYEMLYGL PPFYSRNTAE MYDNILNKPL 
    QLKPNITNSA RHLLEGLLQK DRTKRLGAKD DFMEIKSHIF FSLINWDDLI NKKITPPFNP 
    NVSGPSDLRH FDPEFTEEPV PSSIGRSPDS ILVTASVKEA AEAFLGFSYA PPVDSFL

Genular Protein ID: 916340085

Symbol: E9Q8C1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 404
  • Mass: 45958
  • Checksum: CCB7ADEFBCECF264
  • Sequence:
  • MKQRRMGLND FIQKIASNTY ACKHAEVQSI LKMSHPQEPE LMNANPSPPP SPSQQINLGP 
    SSNPHAKPSD FHFLKVIGKG SFGKVLLARH KAEEVFYAVK VLQKKAILKK KEEKHIMSER 
    NVLLKNVKHP FLVGLHFSFQ TADKLYFVLD YINGGELFYH LQRERCFLEP RARFYAAEIA 
    SALGYLHSLN IVYRDLKPEN ILLDSQGHIV LTDFGLCKEN IEHNGTTSTF CGTPEYLAPE 
    VLHKQPYDRT VDWWCLGAVL YEMLYGLPPF YSRNTAEMYD NILNKPLQLK PNITNSARHL 
    LEGLLQKDRT KRLGAKDDFM EIKSHIFFSL INWDDLINKK ITPPFNPNVS GPSDLRHFDP 
    EFTEEPVPSS IGRSPDSILV TASVKEAAEA FLGFSYAPPV DSFL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.