Details for: AK2

Gene ID: 204

Symbol: AK2

Ensembl ID: ENSG00000004455

Description: adenylate kinase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 233.5655
    Cell Significance Index: -36.3300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 122.9482
    Cell Significance Index: -31.1900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 110.1596
    Cell Significance Index: -45.3800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 95.9737
    Cell Significance Index: -38.9900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 93.3868
    Cell Significance Index: -44.0900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 85.4418
    Cell Significance Index: -43.9500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 65.6014
    Cell Significance Index: -44.0200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 41.3096
    Cell Significance Index: -39.4400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.7563
    Cell Significance Index: -41.6200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.9943
    Cell Significance Index: -34.8100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.9882
    Cell Significance Index: -43.3600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.7864
    Cell Significance Index: -33.1300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.4569
    Cell Significance Index: -16.3200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.1109
    Cell Significance Index: 284.2900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 1.8838
    Cell Significance Index: 50.3900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.6244
    Cell Significance Index: 12.9700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.5237
    Cell Significance Index: 113.5600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.4629
    Cell Significance Index: 39.8200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.4623
    Cell Significance Index: 68.1800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.2376
    Cell Significance Index: 33.0500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.2207
    Cell Significance Index: 143.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.1708
    Cell Significance Index: 55.0300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.0443
    Cell Significance Index: 54.2500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.0163
    Cell Significance Index: 183.2100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.9748
    Cell Significance Index: 125.9400
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.9700
    Cell Significance Index: 10.5500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9595
    Cell Significance Index: 524.0300
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.9074
    Cell Significance Index: 6.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8816
    Cell Significance Index: 108.4000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8730
    Cell Significance Index: 39.5700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8685
    Cell Significance Index: 141.2500
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.8397
    Cell Significance Index: 5.1700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.8384
    Cell Significance Index: 17.5500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.7944
    Cell Significance Index: 7.3200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.7849
    Cell Significance Index: 27.2800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7659
    Cell Significance Index: 152.0000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7436
    Cell Significance Index: 52.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7351
    Cell Significance Index: 100.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7074
    Cell Significance Index: 45.6400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6785
    Cell Significance Index: 299.9900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.6528
    Cell Significance Index: 83.6800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6520
    Cell Significance Index: 130.7900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.6378
    Cell Significance Index: 16.7700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5863
    Cell Significance Index: 529.3900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5664
    Cell Significance Index: 15.8300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4848
    Cell Significance Index: 37.2100
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.3709
    Cell Significance Index: 8.5700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3450
    Cell Significance Index: 123.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3188
    Cell Significance Index: 54.4300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2862
    Cell Significance Index: 8.2100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2349
    Cell Significance Index: 6.9000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1895
    Cell Significance Index: 36.0600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1833
    Cell Significance Index: 11.5600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1715
    Cell Significance Index: 3.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1544
    Cell Significance Index: 8.0400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1418
    Cell Significance Index: 14.0300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1334
    Cell Significance Index: 1.5900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.1234
    Cell Significance Index: 1.5800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0842
    Cell Significance Index: 63.7100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0699
    Cell Significance Index: 128.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0674
    Cell Significance Index: 103.7700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0541
    Cell Significance Index: 101.9200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0319
    Cell Significance Index: 23.3600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0174
    Cell Significance Index: 23.6800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0107
    Cell Significance Index: 0.1800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0009
    Cell Significance Index: 0.0100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0003
    Cell Significance Index: 0.1900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0060
    Cell Significance Index: -2.7200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0102
    Cell Significance Index: -6.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0150
    Cell Significance Index: -11.0900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0230
    Cell Significance Index: -2.3500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0342
    Cell Significance Index: -19.2600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0371
    Cell Significance Index: -1.3100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0772
    Cell Significance Index: -8.8100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0908
    Cell Significance Index: -19.1200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0936
    Cell Significance Index: -2.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0994
    Cell Significance Index: -3.1900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.1106
    Cell Significance Index: -1.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1210
    Cell Significance Index: -14.1000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1300
    Cell Significance Index: -37.4100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1396
    Cell Significance Index: -7.3300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1514
    Cell Significance Index: -22.0100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.1710
    Cell Significance Index: -3.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1862
    Cell Significance Index: -21.3300
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.1864
    Cell Significance Index: -1.1900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2190
    Cell Significance Index: -13.4600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.2262
    Cell Significance Index: -1.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2299
    Cell Significance Index: -12.9000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2668
    Cell Significance Index: -3.6400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2865
    Cell Significance Index: -8.2600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2986
    Cell Significance Index: -8.0000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3014
    Cell Significance Index: -6.5300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3084
    Cell Significance Index: -5.2900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.3163
    Cell Significance Index: -4.7400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3165
    Cell Significance Index: -25.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3174
    Cell Significance Index: -21.3400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3363
    Cell Significance Index: -3.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3583
    Cell Significance Index: -37.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4144
    Cell Significance Index: -10.3600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4538
    Cell Significance Index: -6.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AK2 exhibits a unique substrate specificity, with a preference for ADP and ATP, and is also capable of interconverting other nucleotides, such as AMP and GMP. Its activity is essential for maintaining the energy balance within cells, particularly in high-energy-demanding tissues like the heart and skeletal muscle. Additionally, AK2 has been implicated in the regulation of cell proliferation, differentiation, and survival, underscoring its role as a key player in various cellular processes. **Pathways and Functions:** AK2 is involved in several key pathways, including: 1. **Adenylate Kinase Activity:** AK2 catalyzes the interconversion of ADP and ATP, facilitating the transfer of phosphate groups between these molecules. 2. **Adp Biosynthetic Process:** AK2 plays a crucial role in generating ADP from ATP, a process essential for maintaining energy homeostasis within cells. 3. **Amp Metabolic Process:** AK2 interconverts AMP and ADP, regulating the balance of these nucleotides and maintaining cellular energy homeostasis. 4. **Atp Metabolic Process:** AK2 is involved in the regulation of ATP metabolism, influencing the production and utilization of ATP within cells. 5. **Cytoplasmic and Mitochondrial Functions:** AK2 is localized to both the cytoplasm and mitochondria, where it plays a critical role in regulating energy metabolism and maintaining cellular homeostasis. **Clinical Significance:** Dysregulation of AK2 has been implicated in various diseases, including: 1. **Neurodegenerative Disorders:** AK2 has been shown to play a role in the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's, where energy metabolism is disrupted. 2. **Cancer:** AK2 has been implicated in the regulation of cell proliferation and differentiation, making it a potential target for cancer therapy. 3. **Cardiovascular Disease:** AK2 has been shown to play a role in the regulation of energy metabolism in the heart, making it a potential therapeutic target for cardiovascular disease. 4. **Reproductive Disorders:** AK2 has been implicated in the regulation of sperm function and fertility, highlighting its importance in reproductive health. In conclusion, AK2 is a multifaceted enzyme with a critical role in maintaining energy homeostasis and regulating various cellular processes. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the molecular mechanisms underlying AK2 function and its potential therapeutic applications.

Genular Protein ID: 3158744612

Symbol: KAD2_HUMAN

Name: N/A

UniProtKB Accession Codes:

P54819 A8K6L1 B4DHH7 B4DL64 Q16856 Q5EB54 Q5TIF7 Q8TCY2 Q8TCY3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 15 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 6 EC 1 EMBL 18 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 2 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 5 Rhea 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8843353

Title: Cloning and characterization of cDNA for human adenylate kinase 2A.

PubMed ID: 8843353

DOI: 10.1080/15216549600201931

PubMed ID: 9504408

Title: Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissues.

PubMed ID: 9504408

DOI: 10.1093/oxfordjournals.jbchem.a021915

PubMed ID: 9434148

Title: cDNA cloning and tissue-specific expression of the gene encoding human adenylate kinase isozyme 2.

PubMed ID: 9434148

DOI: 10.1016/s0167-4781(97)00193-0

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 19043417

Title: Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.

PubMed ID: 19043417

DOI: 10.1038/ng.265

PubMed ID: 19043416

Title: Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness.

PubMed ID: 19043416

DOI: 10.1038/ng.278

Sequence Information:

  • Length: 239
  • Mass: 26478
  • Checksum: 86FA94F9EE33629F
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL 
GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE 
KLDSVIEFSI PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE 
KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKA TCKDLVMFI

Genular Protein ID: 1534397822

Symbol: F8W1A4_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8W1A4

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 14 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 HAMAP 2 HAMAP-Rule 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 232
  • Mass: 25631
  • Checksum: 7FAEE1A97D81D401
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL 
GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE 
KLDSVIEFSI PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE 
KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKA TC

Genular Protein ID: 112587425

Symbol: G3V213_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3V213

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 HAMAP 1 HGNC 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 133
  • Mass: 14325
  • Checksum: 120BCEE169339A59
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL 
GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM ADSPQEWPFL 
PRGVQPSKRA HER

Genular Protein ID: 2944593348

Symbol: F8VY04_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8VY04

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HAMAP 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 190
  • Mass: 21226
  • Checksum: D91C7E049AA0810E
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QVSDEMVVEL IEKNLETPLC KNGFLLDGFP 
RTVRQAEMLD DLMEKRKEKL DSVIEFSIPD SLLIRRITGR LIHPKSGRSY HEEFNPPKEP 
MKDDITGEPL IRRSDDNEKA LKIRLQAYHT QTTPLIEYYR KRGIHSAIDA SQTPDVVFAS 
ILAAFSKATS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.