Details for: AK2

Gene ID: 204

Symbol: AK2

Ensembl ID: ENSG00000004455

Description: adenylate kinase 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 3.4
    Marker Score: 3,544
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.1
    Marker Score: 3,718
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.95
    Marker Score: 6,132
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 1.92
    Marker Score: 3,187
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.88
    Marker Score: 7,404
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.88
    Marker Score: 7,258
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 1.88
    Marker Score: 3,928
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.86
    Marker Score: 8,936
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.84
    Marker Score: 15,892
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.84
    Marker Score: 1,955
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.82
    Marker Score: 2,923
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.8
    Marker Score: 1,902
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.79
    Marker Score: 1,019
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.76
    Marker Score: 4,802
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.75
    Marker Score: 4,407
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.71
    Marker Score: 4,063
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.7
    Marker Score: 13,304
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.7
    Marker Score: 1,154
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.7
    Marker Score: 1,806
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.69
    Marker Score: 1,126
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.66
    Marker Score: 5,887
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.65
    Marker Score: 1,666
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 1.64
    Marker Score: 584
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.64
    Marker Score: 2,787
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 1.63
    Marker Score: 2,592
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.61
    Marker Score: 1,740
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.61
    Marker Score: 2,643
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.61
    Marker Score: 2,370
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.61
    Marker Score: 3,926
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.59
    Marker Score: 1,923
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 1.59
    Marker Score: 449
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.58
    Marker Score: 4,700
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 1.58
    Marker Score: 2,883
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.57
    Marker Score: 4,211
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 1.55
    Marker Score: 631
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.54
    Marker Score: 812
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 1.54
    Marker Score: 4,192
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.54
    Marker Score: 1,213
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 1.54
    Marker Score: 821
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.52
    Marker Score: 7,477
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.52
    Marker Score: 15,297
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.51
    Marker Score: 3,563
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.51
    Marker Score: 753
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.51
    Marker Score: 11,208
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 1.5
    Marker Score: 2,316
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.49
    Marker Score: 2,107
  • Cell Name: club cell (CL0000158)
    Fold Change: 1.48
    Marker Score: 1,730
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.47
    Marker Score: 51,018
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.47
    Marker Score: 714
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.47
    Marker Score: 809
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.47
    Marker Score: 3,654
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.46
    Marker Score: 7,699
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.46
    Marker Score: 343
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.46
    Marker Score: 2,095
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.45
    Marker Score: 5,921
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 1.44
    Marker Score: 9,388
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.44
    Marker Score: 1,203
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.43
    Marker Score: 6,180
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.43
    Marker Score: 1,904
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.42
    Marker Score: 1,832
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.42
    Marker Score: 550
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 1.41
    Marker Score: 1,326
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.4
    Marker Score: 1,320
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 1.4
    Marker Score: 692
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: 1.4
    Marker Score: 875
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.39
    Marker Score: 3,159
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 1.38
    Marker Score: 18,267
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 1.38
    Marker Score: 1,476
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.37
    Marker Score: 15,921
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 1.37
    Marker Score: 1,938
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.37
    Marker Score: 674
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.36
    Marker Score: 2,368
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 1.35
    Marker Score: 391
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.34
    Marker Score: 542
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.34
    Marker Score: 8,567
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.34
    Marker Score: 974
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 1.34
    Marker Score: 340
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.32
    Marker Score: 903
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.32
    Marker Score: 882
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.32
    Marker Score: 4,875
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.32
    Marker Score: 1,335
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.31
    Marker Score: 44,505
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.31
    Marker Score: 256
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 1.31
    Marker Score: 979
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.3
    Marker Score: 945
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.3
    Marker Score: 2,961
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 1.3
    Marker Score: 480
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.3
    Marker Score: 325
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.29
    Marker Score: 8,432
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.28
    Marker Score: 1,716
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.27
    Marker Score: 702
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.27
    Marker Score: 446
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.27
    Marker Score: 604
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 1.27
    Marker Score: 1,587
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.27
    Marker Score: 406
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.26
    Marker Score: 302
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 1.25
    Marker Score: 788
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 1.25
    Marker Score: 471
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 1.25
    Marker Score: 1,112
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 1.25
    Marker Score: 1,459

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AK2 exhibits a unique substrate specificity, with a preference for ADP and ATP, and is also capable of interconverting other nucleotides, such as AMP and GMP. Its activity is essential for maintaining the energy balance within cells, particularly in high-energy-demanding tissues like the heart and skeletal muscle. Additionally, AK2 has been implicated in the regulation of cell proliferation, differentiation, and survival, underscoring its role as a key player in various cellular processes. **Pathways and Functions:** AK2 is involved in several key pathways, including: 1. **Adenylate Kinase Activity:** AK2 catalyzes the interconversion of ADP and ATP, facilitating the transfer of phosphate groups between these molecules. 2. **Adp Biosynthetic Process:** AK2 plays a crucial role in generating ADP from ATP, a process essential for maintaining energy homeostasis within cells. 3. **Amp Metabolic Process:** AK2 interconverts AMP and ADP, regulating the balance of these nucleotides and maintaining cellular energy homeostasis. 4. **Atp Metabolic Process:** AK2 is involved in the regulation of ATP metabolism, influencing the production and utilization of ATP within cells. 5. **Cytoplasmic and Mitochondrial Functions:** AK2 is localized to both the cytoplasm and mitochondria, where it plays a critical role in regulating energy metabolism and maintaining cellular homeostasis. **Clinical Significance:** Dysregulation of AK2 has been implicated in various diseases, including: 1. **Neurodegenerative Disorders:** AK2 has been shown to play a role in the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's, where energy metabolism is disrupted. 2. **Cancer:** AK2 has been implicated in the regulation of cell proliferation and differentiation, making it a potential target for cancer therapy. 3. **Cardiovascular Disease:** AK2 has been shown to play a role in the regulation of energy metabolism in the heart, making it a potential therapeutic target for cardiovascular disease. 4. **Reproductive Disorders:** AK2 has been implicated in the regulation of sperm function and fertility, highlighting its importance in reproductive health. In conclusion, AK2 is a multifaceted enzyme with a critical role in maintaining energy homeostasis and regulating various cellular processes. Its dysregulation has been implicated in various diseases, highlighting the need for further research into the molecular mechanisms underlying AK2 function and its potential therapeutic applications.

Genular Protein ID: 3158744612

Symbol: KAD2_HUMAN

Name: N/A

UniProtKB Accession Codes:

P54819 A8K6L1 B4DHH7 B4DL64 Q16856 Q5EB54 Q5TIF7 Q8TCY2 Q8TCY3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChEBI 15 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 6 EC 1 EMBL 18 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HAMAP 2 HAMAP-Rule 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 2 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 5 Rhea 1 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8843353

Title: Cloning and characterization of cDNA for human adenylate kinase 2A.

PubMed ID: 8843353

DOI: 10.1080/15216549600201931

PubMed ID: 9504408

Title: Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in human muscle tissues.

PubMed ID: 9504408

DOI: 10.1093/oxfordjournals.jbchem.a021915

PubMed ID: 9434148

Title: cDNA cloning and tissue-specific expression of the gene encoding human adenylate kinase isozyme 2.

PubMed ID: 9434148

DOI: 10.1016/s0167-4781(97)00193-0

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 19043417

Title: Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2.

PubMed ID: 19043417

DOI: 10.1038/ng.265

PubMed ID: 19043416

Title: Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness.

PubMed ID: 19043416

DOI: 10.1038/ng.278

Sequence Information:

  • Length: 239
  • Mass: 26478
  • Checksum: 86FA94F9EE33629F
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL 
GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE 
KLDSVIEFSI PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE 
KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKA TCKDLVMFI

Genular Protein ID: 112587425

Symbol: G3V213_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3V213

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HAMAP 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 133
  • Mass: 14325
  • Checksum: 120BCEE169339A59
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL 
GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM ADSPQEWPFL 
PRGVQPSKRA HER

Genular Protein ID: 2944593348

Symbol: F8VY04_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8VY04

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 GenomeRNAi 1 HAMAP 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 190
  • Mass: 21226
  • Checksum: D91C7E049AA0810E
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QVSDEMVVEL IEKNLETPLC KNGFLLDGFP 
RTVRQAEMLD DLMEKRKEKL DSVIEFSIPD SLLIRRITGR LIHPKSGRSY HEEFNPPKEP 
MKDDITGEPL IRRSDDNEKA LKIRLQAYHT QTTPLIEYYR KRGIHSAIDA SQTPDVVFAS 
ILAAFSKATS

Genular Protein ID: 1534397822

Symbol: F8W1A4_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8W1A4

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 14 ChiTaRS 1 DNASU 1 EC 1 EMBL 1 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 GenomeRNAi 1 HAMAP 2 HAMAP-Rule 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 232
  • Mass: 25631
  • Checksum: 7FAEE1A97D81D401
  • Sequence:
    • MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL 
GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE 
KLDSVIEFSI PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE 
KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKA TC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.