Details for: Sh3gl2

Gene ID: 20404

Symbol: Sh3gl2

Ensembl ID: ENSMUSG00000028488

Description: SH3-domain GRB2-like 2

Associated with

Other Information

Genular Protein ID: 3480775261

Symbol: SH3G2_MOUSE

Name: Endophilin-1

UniProtKB Accession Codes:

Q62420 Q3UTL7 Q3UY49 Q8BXS6 Q8VBV1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 DisProt 1 EMBL 9 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 34 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 2 PaxDb 1 Pfam 2 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 9 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9630982

Title: Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins.

PubMed ID: 9630982

DOI: 10.1038/nbt0696-741

PubMed ID: 11978849

Title: Congenic mapping of alcohol and pentobarbital withdrawal liability loci to a <1 centimorgan interval of murine chromosome 4: identification of Mpdz as a candidate gene.

PubMed ID: 11978849

DOI: 10.1523/jneurosci.22-09-03730.2002

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10531379

Title: Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.

PubMed ID: 10531379

DOI: 10.1074/jbc.274.44.31693

PubMed ID: 10490020

Title: Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.

PubMed ID: 10490020

DOI: 10.1038/43613

PubMed ID: 18602463

Title: Ataxin-2 associates with the endocytosis complex and affects EGF receptor trafficking.

PubMed ID: 18602463

DOI: 10.1016/j.cellsig.2008.05.018

PubMed ID: 19481455

Title: The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1.

PubMed ID: 19481455

DOI: 10.1016/j.cub.2009.05.022

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21849472

Title: Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB early endocytic trafficking and signaling from early endosomes.

PubMed ID: 21849472

DOI: 10.1091/mbc.e11-04-0308

PubMed ID: 16023669

Title: Crystal structure of the endophilin-A1 BAR domain.

PubMed ID: 16023669

DOI: 10.1016/j.jmb.2005.06.013

PubMed ID: 28891236

Title: A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity.

PubMed ID: 28891236

DOI: 10.1002/humu.23336

Sequence Information:

  • Length: 352
  • Mass: 39955
  • Checksum: 8C2B6F0FB245DCD3
  • Sequence:
    • MSVAGLKKQF HKATQKVSEK VGGAEGTKLD DDFKEMERKV DVTSRAVMEI MTKTIEYLQP 
NPASRAKLSM INTMSKIRGQ EKGPGYPQAE ALLAEAMLKF GRELGDDCNF GPALGEVGEA 
MRELSEVKDS LDMEVKQNFI DPLQNLHDKD LREIQHHLKK LEGRRLDFDY KKKRQGKIPD 
EELRQALEKF DESKEIAESS MFNLLEMDIE QVSQLSALVQ AQLEYHKQAV QILQQVTVRL 
EERIRQASSQ PRREYQPKPR MSLEFATGDS TQPNGGLSHT GTPKPPGVQM DQPCCRALYD 
FEPENEGELG FKEGDIITLT NQIDENWYEG MLHGQSGFFP INYVEILVAL PH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.