Genular: Defining Cellular Identity and Function

Details for: St3gal1

Gene ID: 20442

Symbol: St3gal1

Ensembl ID: ENSMUSG00000013846

Description: ST3 beta-galactoside alpha-2,3-sialyltransferase 1

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-MMU-446193)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Keratan sulfate/keratin metabolism
(R-MMU-1638074)
Keratan sulfate biosynthesis
(R-MMU-2022854)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of proteins
(R-MMU-392499)
O-linked glycosylation
(R-MMU-5173105)
O-linked glycosylation of mucins
(R-MMU-913709)
Post-translational protein modification
(R-MMU-597592)
Sialic acid metabolism
(R-MMU-4085001)
Synthesis of substrates in n-glycan biosythesis
(R-MMU-446219)
Termination of o-glycan biosynthesis
(R-MMU-977068)
Beta-d-galactosyl-(1->3)-n-acetyl-beta-d-galactosaminide alpha-2,3- sialyltransferase
(GO:0047288)
Beta-galactoside (cmp) alpha-2,3-sialyltransferase activity
(GO:0003836)
Extracellular region
(GO:0005576)
Ganglioside biosynthetic process via lactosylceramide
(GO:0010706)
Glycosyltransferase activity
(GO:0016757)
Golgi apparatus
(GO:0005794)
Golgi medial cisterna membrane
(GO:1990675)
Golgi trans cisterna membrane
(GO:1990676)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Memory b cell differentiation
(GO:0002319)
Negative regulation of activated cd8-positive, alpha-beta t cell apoptotic process
(GO:1905403)
Protein glycosylation
(GO:0006486)
Protein phosphorylation
(GO:0006468)
Protein sialylation
(GO:1990743)
Sialylation
(GO:0097503)
Sialyltransferase activity
(GO:0008373)
Trans-golgi network membrane
(GO:0032588)
Transferase activity
(GO:0016740)

Other Information

Proteins

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

Genular Protein ID: 2111110049

Symbol: SIA4A_MOUSE

Name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

UniProtKB Accession Codes:

P54751 Q11202

Database IDs:

Citations:

PubMed ID: 8375377

Title: Molecular cloning and expression of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase from mouse brain.

PubMed ID: 8375377

DOI: 10.1111/j.1432-1033.1993.tb18155.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8144500

Title: Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase.

PubMed ID: 8144500

DOI: 10.1016/s0021-9258(17)36985-5

PubMed ID: 9184827

Title: Mouse beta-galactoside alpha2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression.

PubMed ID: 9184827

DOI: 10.1093/glycob/7.4.469

PubMed ID: 10755614

Title: The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis.

PubMed ID: 10755614

DOI: 10.1016/s1074-7613(00)80180-6

Sequence Information:

Length: 337
Mass: 39073
Checksum: CB54929D1EC047D1
Sequence:

MRRKTLKYLT FFLLFIFLTS FVLNYSNTGV PSAWFPKQML LELSENFRRF IKSQPCTCRH 
CISQDKVSYW FDQRFNKTMQ PLLTVHNALM EEDTYRWWLR LQRERKPNNL SDTVKELFRL 
VPGNVDPMLN KRLVGCRRCA VVGNSGNLKD SSYGPEIDSH DFVLRMNKAP TVGFEADVGS 
RTTHHLVYPE SFRELGENVN MVLVPFKTTD LQWVISATTT GTITHTYVPV PPKIKVKQEK 
ILIYHPAFIK YVFDNWLQGH GRYPSTGILS IIFSIHICDE VDLYGFGADS KGNWHHYWEN 
NPSAGAFRKT GVHDGDFEYN ITTTLAAINK IRIFKGR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: St3gal1

Associated with

Other Information

Molecular cloning and expression of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase from mouse brain. PubMed ID: 8375377

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase. PubMed ID: 8144500