Genular: Defining Cellular Identity and Function

Details for: St3gal4

Gene ID: 20443

Symbol: St3gal4

Ensembl ID: ENSMUSG00000032038

Description: ST3 beta-galactoside alpha-2,3-sialyltransferase 4

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-MMU-446193)
Blood group systems biosynthesis
(R-MMU-9033658)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Keratan sulfate/keratin metabolism
(R-MMU-1638074)
Keratan sulfate biosynthesis
(R-MMU-2022854)
Lewis blood group biosynthesis
(R-MMU-9037629)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of proteins
(R-MMU-392499)
N-glycan antennae elongation
(R-MMU-975577)
N-glycan antennae elongation in the medial/trans-golgi
(R-MMU-975576)
O-linked glycosylation
(R-MMU-5173105)
O-linked glycosylation of mucins
(R-MMU-913709)
Post-translational protein modification
(R-MMU-597592)
Sialic acid metabolism
(R-MMU-4085001)
Synthesis of substrates in n-glycan biosythesis
(R-MMU-446219)
Termination of o-glycan biosynthesis
(R-MMU-977068)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Beta-d-galactosyl-(1->3)-n-acetyl-beta-d-galactosaminide alpha-2,3- sialyltransferase
(GO:0047288)
Beta-galactoside (cmp) alpha-2,3-sialyltransferase activity
(GO:0003836)
Cognition
(GO:0050890)
Glycolipid biosynthetic process
(GO:0009247)
Glycoprotein biosynthetic process
(GO:0009101)
Glycosyltransferase activity
(GO:0016757)
Golgi apparatus
(GO:0005794)
Lipid glycosylation
(GO:0030259)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
N-acetyllactosaminide alpha-2,3-sialyltransferase activity
(GO:0008118)
Oligosaccharide biosynthetic process
(GO:0009312)
Positive regulation of blood coagulation
(GO:0030194)
Positive regulation of leukocyte tethering or rolling
(GO:1903238)
Protein glycosylation
(GO:0006486)
Protein sialylation
(GO:1990743)
Sialylation
(GO:0097503)
Sialyltransferase activity
(GO:0008373)
Transferase activity
(GO:0016740)

Other Information

Proteins

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

Genular Protein ID: 1884370710

Symbol: SIA4C_MOUSE

Name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

UniProtKB Accession Codes:

Q91Y74 P97354 Q61325

Database IDs:

Citations:

PubMed ID: 9184827

Title: Mouse beta-galactoside alpha2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression.

PubMed ID: 9184827

DOI: 10.1093/glycob/7.4.469

PubMed ID: 11389169

Title: Differential expression of mRNAs for sialyltransferase isoenzymes induced in the hippocampus of mouse following kindled seizures.

PubMed ID: 11389169

DOI: 10.1046/j.1471-4159.2001.00319.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12097641

Title: Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.

PubMed ID: 12097641

DOI: 10.1073/pnas.142005099

PubMed ID: 18519646

Title: Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.

PubMed ID: 18519646

DOI: 10.1084/jem.20070846

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25498912

Title: ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes.

PubMed ID: 25498912

DOI: 10.1182/blood-2014-07-588590

Sequence Information:

Length: 333
Mass: 38058
Checksum: 4EAB2F09502B54F4
Sequence:

MTSKSHWKLL ALALVLVVVM VWYSISREDR YIEFFYFPIS EKKEPCFQGE AERQASKIFG 
NRSREQPIFL QLKDYFWVKT PSTYELPFGT KGSEDLLLRV LAITSYSIPE SIKSLECRRC 
VVVGNGHRLR NSSLGGVINK YDVVIRLNNA PVAGYEGDVG SKTTIRLFYP ESAHFDPKIE 
NNPDTLLVLV AFKAMDFHWI ETILSDKKRV RKGFWKQPPL IWDVNPKQVR ILNPFFMEIA 
ADKLLSLPIQ QPRKIKQKPT TGLLAITLAL HLCDLVHIAG FGYPDASNKK QTIHYYEQIT 
LKSMAGSGHN VSQEAIAIKR MLEMGAVKNL TYF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: St3gal4

Associated with

Other Information

Mouse beta-galactoside alpha2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression. PubMed ID: 9184827

Differential expression of mRNAs for sialyltransferase isoenzymes induced in the hippocampus of mouse following kindled seizures. PubMed ID: 11389169

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands. PubMed ID: 12097641

Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. PubMed ID: 18519646

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes. PubMed ID: 25498912