Genular: Defining Cellular Identity and Function

Details for: St3gal2

Gene ID: 20444

Symbol: St3gal2

Ensembl ID: ENSMUSG00000031749

Description: ST3 beta-galactoside alpha-2,3-sialyltransferase 2

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-MMU-446193)
Glycosaminoglycan metabolism
(R-MMU-1630316)
Glycosphingolipid biosynthesis
(R-MMU-9840309)
Glycosphingolipid metabolism
(R-MMU-1660662)
Keratan sulfate/keratin metabolism
(R-MMU-1638074)
Keratan sulfate biosynthesis
(R-MMU-2022854)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Metabolism of lipids
(R-MMU-556833)
Metabolism of proteins
(R-MMU-392499)
O-linked glycosylation
(R-MMU-5173105)
O-linked glycosylation of mucins
(R-MMU-913709)
Post-translational protein modification
(R-MMU-597592)
Sialic acid metabolism
(R-MMU-4085001)
Sphingolipid metabolism
(R-MMU-428157)
Synthesis of substrates in n-glycan biosythesis
(R-MMU-446219)
Termination of o-glycan biosynthesis
(R-MMU-977068)
Beta-d-galactosyl-(1->3)-n-acetyl-beta-d-galactosaminide alpha-2,3- sialyltransferase
(GO:0047288)
Beta-galactoside (cmp) alpha-2,3-sialyltransferase activity
(GO:0003836)
Extracellular region
(GO:0005576)
Ganglioside biosynthetic process via lactosylceramide
(GO:0010706)
Globoside biosynthetic process via lactosylceramide
(GO:0010707)
Glycolipid biosynthetic process
(GO:0009247)
Glycoprotein biosynthetic process
(GO:0009101)
Glycosyltransferase activity
(GO:0016757)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Lipid glycosylation
(GO:0030259)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Oligosaccharide biosynthetic process
(GO:0009312)
Protein glycosylation
(GO:0006486)
Protein homodimerization activity
(GO:0042803)
Protein sialylation
(GO:1990743)
Sialylation
(GO:0097503)
Sialyltransferase activity
(GO:0008373)
Transferase activity
(GO:0016740)

Other Information

Proteins

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

Genular Protein ID: 4079002497

Symbol: SIA4B_MOUSE

Name: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

UniProtKB Accession Codes:

Q11204 Q8BPL0

Database IDs:

Citations:

PubMed ID: 8144500

Title: Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase.

PubMed ID: 8144500

DOI: 10.1016/s0021-9258(17)36985-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9184827

Title: Mouse beta-galactoside alpha2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression.

PubMed ID: 9184827

DOI: 10.1093/glycob/7.4.469

PubMed ID: 22735313

Title: Biosynthesis of the major brain gangliosides GD1a and GT1b.

PubMed ID: 22735313

DOI: 10.1093/glycob/cws103

PubMed ID: 32030804

Title: GT1b functions as a novel endogenous agonist of toll-like receptor 2 inducing neuropathic pain.

PubMed ID: 32030804

DOI: 10.15252/embj.2019102214

Sequence Information:

Length: 350
Mass: 40130
Checksum: 3C59FA39E6A03E4D
Sequence:

MKCSLRVWFL SMAFLLVFIM SLLFTYSHHS MATLPYLDSG ALGGTHRVKL VPGYSGLQRL 
GKEGLLGRNC ACSRCMGDAS TSEWFDSHFD GNISPVWTRD NMNLPPDVQR WWMMLQPQFK 
SHNTNEVLEK LFQIVPGENP YRFRDPQQCR RCAVVGNSGN LRGSGYGQEV DSHNFIMRMN 
QAPTVGFEKD VGSRTTHHFM YPESAKNLPA NVSFVLVPFK ALDLMWIASA LSTGQIRFTY 
APVKSFLRVD KEKVQIYNPA FFKYIHDRWT EHHGRYPSTG MLVLFFALHV CDEVNVYGFG 
ADSRGNWHHY WENNRYAGEF RKTGVHDADF EAHIIDMLAK ASKIEVYRGN

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: St3gal2

Associated with

Other Information

Cloning and expression of cDNA for a new type of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase. PubMed ID: 8144500

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mouse beta-galactoside alpha2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression. PubMed ID: 9184827

Biosynthesis of the major brain gangliosides GD1a and GT1b. PubMed ID: 22735313