Genular: Defining Cellular Identity and Function

Details for: St8sia1

Gene ID: 20449

Symbol: St8sia1

Ensembl ID: ENSMUSG00000030283

Description: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-MMU-446193)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Sialic acid metabolism
(R-MMU-4085001)
Synthesis of substrates in n-glycan biosythesis
(R-MMU-446219)
Alpha-n-acetylneuraminate alpha-2,8-sialyltransferase activity
(GO:0003828)
Cell population proliferation
(GO:0008283)
Cellular response to heat
(GO:0034605)
Epithelial cell proliferation
(GO:0050673)
Glycosyltransferase activity
(GO:0016757)
Golgi apparatus
(GO:0005794)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
N-glycan processing
(GO:0006491)
Oligosaccharide metabolic process
(GO:0009311)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Protein glycosylation
(GO:0006486)
Sialyltransferase activity
(GO:0008373)
Sphingolipid metabolic process
(GO:0006665)
Transferase activity
(GO:0016740)

Other Information

Proteins

Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
Q3V3B1_MOUSE

Genular Protein ID: 1739875383

Symbol: SIA8A_MOUSE

Name: Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

UniProtKB Accession Codes:

Q64687 Q8K1C1

Database IDs:

Citations:

PubMed ID: 8910600

Title: Molecular cloning and expression of a fifth type of alpha2,8-sialyltransferase (ST8Sia V). Its substrate specificity is similar to that of SAT-V/III, which synthesize GD1c, GT1a, GQ1b and GT3.

PubMed ID: 8910600

DOI: 10.1074/jbc.271.46.29366

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15843597

Title: The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach.

PubMed ID: 15843597

DOI: 10.1093/glycob/cwi063

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 355
Mass: 40324
Checksum: 220BD56BBEE6E6C6
Sequence:

MSPCGRALHT SRGAMAMLAR KFPRTRLPVG ASALCVVVLC WLYIFPVYRL PNEKEIVQGV 
LAQRTAWRTN QTSASLFRRQ MEDCCDPAHL FAMTKMNSPM GKSLWYDGEL LYSFTIDNST 
YSLFPQATPF QLPLKKCAVV GNGGILKMSG CGRQIDEANF VMRCNLPPLS SEYTRDVGSK 
TQLVTANPSI IRQRFENLLW SRKKFVDNMK IYNHSYIYMP AFSMKTGTEP SLRVYYTLKD 
VGANQTVLFA NPNFLRNIGK FWKSRGIHAK RLSTGLFLVS AALGLCEEVS IYGFWPFSVN 
MQGDPISHHY YDNVLPFSGY HAMPEEFLQL WYLHKIGALR MQLDPCEEPS PQPTS

Genular Protein ID: 1463137004

Symbol: Q3V3B1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3V3B1

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 275
Mass: 31293
Checksum: 948E84CD64AC63E8
Sequence:

MEDCCDPAHL FAMTKMNSPM GKSLWYDGEL LYSFTIDNST YSLFPQATPF QLPLKKCAVV 
GNGGILKMSG CGRQIDEANF VMRCNLPPLS SEYTRDVGSK TQLVTANPSI IRQRFENLLW 
SRKKFVDNMK IYNHSYIYMP AFSMKTGTEP SLRVYYTLKD VGANQTVLFA NPNFLRNIGK 
FWKSRGIHAK RLSTGLFLVS AALGLCEEVS IYGFWPFSVN MQGDPISHHY YDNVLPFSGY 
HAMPEEFLQL WYLHKIGALR MQLDPCEEPS PQPTS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: St8sia1

Associated with

Other Information

Molecular cloning and expression of a fifth type of alpha2,8-sialyltransferase (ST8Sia V). Its substrate specificity is similar to that of SAT-V/III, which synthesize GD1c, GT1a, GQ1b and GT3. PubMed ID: 8910600

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. PubMed ID: 15843597

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073