Genular: Defining Cellular Identity and Function

Details for: St8sia2

Gene ID: 20450

Symbol: St8sia2

Ensembl ID: ENSMUSG00000025789

Description: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

Associated with

Asparagine n-linked glycosylation
(R-MMU-446203)
Axon guidance
(R-MMU-422475)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-MMU-446193)
Developmental biology
(R-MMU-1266738)
Metabolism of proteins
(R-MMU-392499)
N-glycan antennae elongation
(R-MMU-975577)
N-glycan antennae elongation in the medial/trans-golgi
(R-MMU-975576)
Ncam1 interactions
(R-MMU-419037)
Ncam signaling for neurite out-growth
(R-MMU-375165)
Nervous system development
(R-MMU-9675108)
Post-translational protein modification
(R-MMU-597592)
Sialic acid metabolism
(R-MMU-4085001)
Synthesis of substrates in n-glycan biosythesis
(R-MMU-446219)
Transport to the golgi and subsequent modification
(R-MMU-948021)
Alpha-n-acetylneuraminate alpha-2,8-sialyltransferase activity
(GO:0003828)
Early endosome
(GO:0005769)
Extracellular region
(GO:0005576)
Ganglioside biosynthetic process
(GO:0001574)
Glycosyltransferase activity
(GO:0016757)
Golgi apparatus
(GO:0005794)
Membrane
(GO:0016020)
N-glycan processing
(GO:0006491)
Neuron projection extension
(GO:1990138)
Oligosaccharide metabolic process
(GO:0009311)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of neuron apoptotic process
(GO:0043525)
Positive regulation of synapse assembly
(GO:0051965)
Protein binding
(GO:0005515)
Protein glycosylation
(GO:0006486)
Recycling endosome
(GO:0055037)
Sialylation
(GO:0097503)
Sialyltransferase activity
(GO:0008373)
Transferase activity
(GO:0016740)

Other Information

Proteins

Alpha-2,8-sialyltransferase 8B

Genular Protein ID: 3176903223

Symbol: SIA8B_MOUSE

Name: Alpha-2,8-sialyltransferase 8B

UniProtKB Accession Codes:

O35696 Q4VA47

Database IDs:

Citations:

PubMed ID: 8939967

Title: Genomic structure and promoter activity of the mouse polysialic acid synthase gene (mST8Sia II). Brain-specific expression from a TATA-less GC-rich sequence.

PubMed ID: 8939967

DOI: 10.1074/jbc.271.47.30167

PubMed ID: 7875291

Title: Enzymatic activity of a developmentally regulated member of the sialyltransferase family (STX): evidence for alpha 2,8-sialyltransferase activity toward N-linked oligosaccharides.

PubMed ID: 7875291

DOI: 10.1016/0014-5793(95)00059-i

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 375
Mass: 42411
Checksum: 34F43C519A0236CF
Sequence:

MQLQFRSWML AALTLLVVFL IFADISEIEE EIGNSGGRGT IRSAVNSLHS KSNRAEVVIN 
GSSPPAVADR SNESLKHNIQ PASSKWRHNQ TLSLRIRKQI LKFLDAEKDI SVLKGTLKPG 
DIIHYIFDRD STMNVSQNLY ELLPRTSPLK NKHFQTCAIV GNSGVLLNSG CGQEIDTHSF 
VIRCNLAPVQ EYARDVGLKT DLVTMNPSVI QRAFEDLVNA TWREKLLQRL HGLNGSILWI 
PAFMARGGKE RVEWVNALIL KHHVNVRTAY PSLRLLHAVR GYWLTNKVHI KRPTTGLLMY 
TLATRFCNQI YLYGFWPFPL DQNQNPVKYH YYDSLKYGYT SQASPHTMPL EFKALKSLHE 
QGALKLTVGQ CDGAT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.