Details for: Sim1

Gene ID: 20464

Symbol: Sim1

Ensembl ID: ENSMUSG00000019913

Description: single-minded family bHLH transcription factor 1

Associated with

Other Information

Genular Protein ID: 2757342514

Symbol: SIM1_MOUSE

Name: Single-minded homolog 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8812055

Title: Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.

PubMed ID: 8812055

DOI: 10.1006/mcne.1996.0001

PubMed ID: 8875433

Title:

PubMed ID: 8875433

DOI: 10.1006/mcne.1996.0037

PubMed ID: 9199934

Title: Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.

PubMed ID: 9199934

DOI: 10.1101/gr.7.6.615

PubMed ID: 8927054

Title: Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis.

PubMed ID: 8927054

DOI: 10.1128/mcb.16.10.5865

PubMed ID: 9020169

Title: Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein.

PubMed ID: 9020169

DOI: 10.1074/jbc.272.7.4451

PubMed ID: 27782878

Title: NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.

PubMed ID: 27782878

DOI: 10.7554/elife.18790

Sequence Information:

  • Length: 765
  • Mass: 85541
  • Checksum: B1A7F7DA8578CD17
  • Sequence:
  • MKEKSKNAAR TRREKENSEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL KMRVVFPEGL 
    GEAWGHTSRT SPLDNVGREL GSHLLQTLDG FIFVVAPDGK IMYISETASV HLGLSQVELT 
    GNSIYEYIHP ADHDEMTAVL TAHQPYHSHF VQEYEIERSF FLRMKCVLAK RNAGLTCGGY 
    KVIHCSGYLK IRQYSLDMSP FDGCYQNVGL VAVGHSLPPS AVTEIKLHSN MFMFRASLDM 
    KLIFLDSRVA ELTGYEPQDL IEKTLYHHVH GCDTFHLRCA HHLLLVKGQV TTKYYRFLAK 
    QGGWVWVQSY ATIVHNSRSS RPHCIVSVNY VLTDTEYKGL QLSLDQISAS KPTFSYTSSS 
    TPTISDNRKG AKSRLSSSKS KSRTSPYPQY SGFHTERSES DHDSQWGGSP LTDTASPQLL 
    DPERPGSQHE LSCAYRQFPD RSSLCYGFAL DHSRLVEDRH FHTQACEGGR CEAGRYFLGA 
    PPTGRDPWWG SRAALPLTKA SPESREAYEN SMPHITSIHR IHGRGHWDED SVVSSPDPGS 
    ASESGDRYRT EQYQNSPHEP SKIETLIRAT QQMIKEEENR LQLRKAPPDQ LASINGAGKK 
    HSLCFANYQQ PPPTGEVCHS SALASTSPCD HIQQREGKML SPHENDYDNS PTALSRISSP 
    SSDRITKSSL ILAKDYLHSD MSPHQTAGDH PAISPNCFGS HRQYFDKHAY TLTGYALEHL 
    YDSETIRNYS LGCNGSHFDV TSHLRMQPDP AQGHKGTSVI ITNGS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.