Details for: Six6

Gene ID: 20476

Symbol: Six6

Ensembl ID: ENSMUSG00000021099

Description: sine oculis-related homeobox 6

Associated with

Other Information

Genular Protein ID: 1655812888

Symbol: SIX6_MOUSE

Name: Homeobox protein SIX6

UniProtKB Accession Codes:

Q9QZ28 O88423

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 Ensembl 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9724757

Title: The optx2 homeobox gene is expressed in early precursors of the eye and activates retina-specific genes.

PubMed ID: 9724757

DOI: 10.1073/pnas.95.18.10643

PubMed ID: 10473118

Title: Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk.

PubMed ID: 10473118

DOI: 10.1016/s0925-4773(99)00068-4

PubMed ID: 10381575

Title: Six9 (Optx2), a new member of the Six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development.

PubMed ID: 10381575

DOI: 10.1016/s0925-4773(99)00017-9

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 12050133

Title: Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors.

PubMed ID: 12050133

DOI: 10.1242/dev.129.12.2835

Sequence Information:

  • Length: 246
  • Mass: 27741
  • Checksum: F1332D5E617B2CF1
  • Sequence:
    • MFQLPILNFS PQQVAGVCET LEESGDVERL GRFLWSLPVA PAACEALNKN ESVLRARAIV 
AFHGGNYREL YHILENHKFT KESHAKLQAL WLEAHYQEAE KLRGRPLGPV DKYRVRKKFP 
LPRTIWDGEQ KTHCFKERTR HLLREWYLQD PYPNPSKKRE LAQATGLTPT QVGNWFKNRR 
QRDRAAAAKN RLQQQVLSQG PGRVLRSEGE GTPEVLGVAS SPAASLSSKA ATSAISITSS 
DSECDI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.