Details for: AK4

Gene ID: 205

Symbol: AK4

Ensembl ID: ENSG00000162433

Description: adenylate kinase 4

Associated with

Other Information

Genular Protein ID: 1967786300

Symbol: KAD4_HUMAN

Name: N/A

UniProtKB Accession Codes:

P27144 B2R927 D3DQ62 Q6IBH4 Q6NXQ5 Q8IUU9

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 2 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 22 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 3 EMBL 15 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HAMAP 3 HAMAP-Rule 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 3 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 3 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1639383

Title: Characterization of human adenylate kinase 3 (AK3) cDNA and mapping of the AK3 pseudogene to an intron of the NF1 gene.

PubMed ID: 1639383

DOI: 10.1016/0888-7543(92)90122-9

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11485571

Title: Structure and expression of human mitochondrial adenylate kinase targeted to the mitochondrial matrix.

PubMed ID: 11485571

DOI: 10.1042/0264-6021:3580225

PubMed ID: 19130895

Title: Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase.

PubMed ID: 19130895

DOI: 10.1016/j.biocel.2008.12.002

PubMed ID: 19766732

Title: Evidence of an intact N-terminal translocation sequence of human mitochondrial adenylate kinase 4.

PubMed ID: 19766732

DOI: 10.1016/j.biocel.2009.09.007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23474458

Title: Differential expression of adenylate kinase 4 in the context of disparate stress response strategies of HEK293 and HepG2 cells.

PubMed ID: 23474458

DOI: 10.1016/j.abb.2013.02.014

PubMed ID: 23416111

Title: The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase.

PubMed ID: 23416111

DOI: 10.1016/j.biocel.2013.02.004

PubMed ID: 24767988

Title: A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels.

PubMed ID: 24767988

DOI: 10.1016/j.celrep.2014.03.065

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26980435

Title: Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4.

PubMed ID: 26980435

DOI: 10.1186/s13046-016-0322-2

PubMed ID: 19073142

Title: Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion.

PubMed ID: 19073142

DOI: 10.1016/j.bbrc.2008.12.012

Sequence Information:

  • Length: 223
  • Mass: 25268
  • Checksum: 653341A8EB3BC723
  • Sequence:
    • MASKLLRAVI LGPPGSGKGT VCQRIAQNFG LQHLSSGHFL RENIKASTEV GEMAKQYIEK 
SLLVPDHVIT RLMMSELENR RGQHWLLDGF PRTLGQAEAL DKICEVDLVI SLNIPFETLK 
DRLSRRWIHP PSGRVYNLDF NPPHVHGIDD VTGEPLVQQE DDKPEAVAAR LRQYKDVAKP 
VIELYKSRGV LHQFSGTETN KIWPYVYTLF SNKITPIQSK EAY

Genular Protein ID: 80100134

Symbol: F8VS11_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8VS11

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 DNASU 1 EMBL 5 EPD 1 Ensembl 2 GO 5 Gene3D 1 GeneTree 1 HAMAP 1 HGNC 1 InterPro 5 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 Pfam 3 Proteomes 3 RefSeq 2 RuleBase 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 171
  • Mass: 19781
  • Checksum: 88D269262743092C
  • Sequence:
    • MAKQYIEKSL LVPDHVITRL MMSELENRRG QHWLLDGFPR TLGQAEALDK ICEVDLVISL 
NIPFETLKDR LSRRWIHPPS GRVYNLDFNP PHVHGIDDVT GEPLVQQEDD KPEAVAARLR 
QYKDVAKPVI ELYKSRGVLH QFSGTETNKI WPYVYTLFSN KITPIQSKEA Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.