Details for: Slc19a1

Gene ID: 20509

Symbol: Slc19a1

Ensembl ID: ENSMUSG00000001436

Description: solute carrier family 19 (folate transporter), member 1

Associated with

Other Information

Genular Protein ID: 416430598

Symbol: S19A1_MOUSE

Name: N/A

UniProtKB Accession Codes:

P41438 Q62450 Q62451

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 EMBL 22 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 19 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 3 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 7 Rhea 2 SAM 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 8276792

Title: A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells.

PubMed ID: 8276792

DOI: 10.1016/s0021-9258(17)42301-5

PubMed ID: 8664315

Title: Intestinal folate transport: identification of a cDNA involved in folate transport and the functional expression and distribution of its mRNA.

PubMed ID: 8664315

DOI: 10.1016/0005-2736(96)00005-3

PubMed ID: 7559435

Title: Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line.

PubMed ID: 7559435

DOI: 10.1074/jbc.270.39.22974

PubMed ID: 9161403

Title: Organization, structure and alternate splicing of the murine RFC-1 gene encoding a folate transporter.

PubMed ID: 9161403

DOI: 10.1016/s0378-1119(96)00676-2

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 10787414

Title: Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium.

PubMed ID: 10787414

DOI: 10.1074/jbc.m002328200

PubMed ID: 9111015

Title: RFC-1 gene expression regulates folate absorption in mouse small intestine.

PubMed ID: 9111015

DOI: 10.1074/jbc.272.17.11165

PubMed ID: 9748272

Title: Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate.

PubMed ID: 9748272

DOI: 10.1074/jbc.273.40.25953

PubMed ID: 31511694

Title: SLC19A1 transports immunoreactive cyclic dinucleotides.

PubMed ID: 31511694

DOI: 10.1038/s41586-019-1553-0

Sequence Information:

  • Length: 512
  • Mass: 58150
  • Checksum: 640CB7AD2624BF67
  • Sequence:
    • MVPTGQVAEK QAYEEPRQDH ELKSWRCLVF YLCFFGFMAQ LRPGESFITP FLLERKFTKE 
QVTNEIIPML PYSHLAVLVP VFLLTDYLRY KPVLVLQCLS FVCVWLLLLL GTSVVHMQLM 
EVFYSVTMAA RIAYSSYIFS LVHPSRYQRM ASYSRAAVLL GVFISSVLGQ ALVTVGHIST 
YTLNCVSLGF ILFSLVLSLF LKRPKRSLFF NRSTLARGAL PCELDQMHPG PDRPETRKLD 
RMLGTCRDSF LVRMLSELVE NARQPQLRLW CLWWVFNSSG YYLITYYVHV LWRSTDSSLS 
YNGAVDAAST LLSAITSFSA GFLSIRWTLW SKLVIAGVIA IQASLVFCMF QIRDIWVCYV 
TFVLFRGAYQ FLVPIATFQI ASSLSKELCA LVFGINTFLA TALKTCITLV VSDKRGLGLQ 
VRDQFRIYFI YFLMLSITCF AWAGLDGLRY CQRGRHQPLA QAQELRSPLE TSVQAISLQD 
GDLRGPQPSA PQLLSEDGME DDRGDLRVEA KA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.