Genular: Defining Cellular Identity and Function

Details for: Slc22a2

Gene ID: 20518

Symbol: Slc22a2

Ensembl ID: ENSMUSG00000040966

Description: solute carrier family 22 (organic cation transporter), member 2

Associated with

Abacavir adme
(R-MMU-2161522)
Abacavir transmembrane transport
(R-MMU-2161517)
Drug adme
(R-MMU-9748784)
Na+/cl- dependent neurotransmitter transporters
(R-MMU-442660)
Neuronal system
(R-MMU-112316)
Neurotransmitter clearance
(R-MMU-112311)
Neurotransmitter release cycle
(R-MMU-112310)
Norepinephrine neurotransmitter release cycle
(R-MMU-181430)
Organic cation/anion/zwitterion transport
(R-MMU-549132)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transmission across chemical synapses
(R-MMU-112315)
Transport of bile salts and organic acids, metal ions and amine compounds
(R-MMU-425366)
Transport of small molecules
(R-MMU-382551)
Acetylcholine transmembrane transporter activity
(GO:0005277)
Acetylcholine transport
(GO:0015870)
Amine transmembrane transporter activity
(GO:0005275)
Amine transport
(GO:0015837)
Amino acid import across plasma membrane
(GO:0089718)
Apical plasma membrane
(GO:0016324)
Basal plasma membrane
(GO:0009925)
Basolateral plasma membrane
(GO:0016323)
Cholinergic synapse
(GO:0098981)
Choline transmembrane transporter activity
(GO:0015220)
Choline transport
(GO:0015871)
Dopamine transport
(GO:0015872)
Dopamine uptake
(GO:0090494)
Efflux transmembrane transporter activity
(GO:0015562)
Epinephrine transport
(GO:0048241)
Export across plasma membrane
(GO:0140115)
Histamine transport
(GO:0051608)
Histamine uptake
(GO:0051615)
L-alpha-amino acid transmembrane transport
(GO:1902475)
L-amino acid transmembrane transporter activity
(GO:0015179)
L-arginine import across plasma membrane
(GO:0097638)
L-arginine transmembrane transporter activity
(GO:0061459)
Membrane
(GO:0016020)
Monoamine transmembrane transporter activity
(GO:0008504)
Monoatomic cation transport
(GO:0006812)
Monoatomic ion transport
(GO:0006811)
Neurotransmitter transmembrane transporter activity
(GO:0005326)
Neurotransmitter transport
(GO:0006836)
Norepinephrine transport
(GO:0015874)
Norepinephrine uptake
(GO:0051620)
Organic anion transmembrane transporter activity
(GO:0008514)
Organic cation transmembrane transporter activity
(GO:0015101)
Organic cation transport
(GO:0015695)
Plasma membrane
(GO:0005886)
Positive regulation of gene expression
(GO:0010628)
Presynaptic membrane
(GO:0042734)
Prostaglandin transmembrane transporter activity
(GO:0015132)
Prostaglandin transport
(GO:0015732)
Putrescine transmembrane transporter activity
(GO:0015489)
Putrescine transport
(GO:0015847)
Pyrimidine nucleoside transmembrane transporter activity
(GO:0015214)
Quaternary ammonium group transmembrane transporter activity
(GO:0015651)
Quaternary ammonium group transport
(GO:0015697)
Serotonin transport
(GO:0006837)
Serotonin uptake
(GO:0051610)
Steroid binding
(GO:0005496)
Synaptic vesicle membrane
(GO:0030672)
Thiamine transmembrane transport
(GO:0071934)
Thiamine transmembrane transporter activity
(GO:0015234)
Toxin transmembrane transporter activity
(GO:0019534)
Toxin transport
(GO:1901998)
Transmembrane transport
(GO:0055085)
Transmembrane transporter activity
(GO:0022857)
Xenobiotic transmembrane transporter activity
(GO:0042910)
Xenobiotic transport
(GO:0042908)
Xenobiotic transport across blood-brain barrier
(GO:1990962)

Other Information

Proteins

S22A2_MOUSE

Genular Protein ID: 1072310809

Symbol: S22A2_MOUSE

Name: N/A

UniProtKB Accession Codes:

O70577 Q8BWF6 Q8K4X8

Database IDs:

Citations:

PubMed ID: 10051314

Title: Cloning of the mouse organic cation transporter 2 gene, Slc22a2, from an enhancer-trap transgene integration locus.

PubMed ID: 10051314

DOI: 10.1007/s003359900976

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23458604

Title: Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3.

PubMed ID: 23458604

DOI: 10.1021/mp400024d

PubMed ID: 26979622

Title: A phosphotyrosine switch regulates organic cation transporters.

PubMed ID: 26979622

DOI: 10.1038/ncomms10880

Sequence Information:

Length: 553
Mass: 61831
Checksum: 1E9744F0D5415483
Sequence:

MPTVDDILEH IGEFHLFQKQ TFFLLALLSG AFTPIYVGIV FLGFTPNHHC RSPGVAELSQ 
RCGWSPAEEL NYTVPGLGSA GEVSFLSQCM RYEVDWNQST LDCVDPLSSL AANRSHLPLS 
PCEHGWVYDT PGSSIVTEFN LVCAHSWMLD LFQSLVNVGF FIGAVGIGYL ADRFGRKFCL 
LVTILINAIS GVLMAISPNY AWMLVFRFLQ GLVSKAGWLI GYILITEFVG LGYRRTVGIC 
YQIAFTVGLL ILAGVAYALP NWRWLQFAVT LPNFCFLLYF WCIPESPRWL ISQNKNAKAM 
KIIKHIAKKN GKSVPVSLQS LTADEDTGMK LNPSFLDLVR TPQIRKHTLI LMYNWFTSSV 
LYQGLIMHMG LAGDNIYLDF FYSALVEFPA AFIIILTIDR IGRRYPWAVS NMVAGAACLA 
SVFIPDDLQW LKITVACLGR MGITIAYEMV CLVNAELYPT YIRNLAVLVC SSMCDIGGIV 
TPFLVYRLTD IWLEFPLVVF AVVGLVAGGL VLLLPETKGK ALPETIEDAE KMQRPRKKKE 
KRIYLQVKKA ELS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc22a2

Associated with

Other Information

Cloning of the mouse organic cation transporter 2 gene, Slc22a2, from an enhancer-trap transgene integration locus. PubMed ID: 10051314

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3. PubMed ID: 23458604