Details for: Slc22a5

Gene ID: 20520

Symbol: Slc22a5

Ensembl ID: ENSMUSG00000018900

Description: solute carrier family 22 (organic cation transporter), member 5

Associated with

Other Information

Genular Protein ID: 1374626527

Symbol: S22A5_MOUSE

Name: Organic cation/carnitine transporter 2

UniProtKB Accession Codes:

Q9Z0E8

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 21 ChEMBL 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 33 Gene3D 1 GeneTree 1 Genevisible 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 10 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9916797

Title: Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter.

PubMed ID: 9916797

DOI: 10.1038/5030

PubMed ID: 9837751

Title: A missense mutation of mouse OCTN2, a sodium-dependent carnitine cotransporter, in the juvenile visceral steatosis mouse.

PubMed ID: 9837751

DOI: 10.1006/bbrc.1998.9708

PubMed ID: 10454528

Title: Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.

PubMed ID: 10454528

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11010964

Title: Molecular and functional characterization of organic cation/carnitine transporter family in mice.

PubMed ID: 11010964

DOI: 10.1074/jbc.m005340200

PubMed ID: 15523054

Title: PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2.

PubMed ID: 15523054

DOI: 10.1124/mol.104.002212

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20722056

Title: Cytokine regulation of OCTN2 expression and activity in small and large intestine.

PubMed ID: 20722056

DOI: 10.1002/ibd.21444

Sequence Information:

  • Length: 557
  • Mass: 62780
  • Checksum: 6093F0EE9612B204
  • Sequence:
    • MRDYDEVTAF LGEWGPFQRL IFFLLSASII PNGFNGMSIV FLAGTPEHRC LVPHTVNLSS 
AWRNHSIPLE TKDGRQVPQK CRRYRLATIA NFSELGLEPG RDVDLEQLEQ ESCLDGWEYD 
KDVFLSTIVT EWDLVCKDDW KAPLTTSLFF VGVLMGSFIS GQLSDRFGRK NVLFLTMGMQ 
TGFSFLQVFS VNFEMFTVLF VLVGMGQISN YVAAFVLGTE ILSKSIRIIF ATLGVCIFYA 
FGFMVLPLFA YFIRDWRMLL LALTVPGVLC GALWWFIPES PRWLISQGRI KEAEVIIRKA 
AKINGIVAPS TIFDPSELQD LNSTKPQLHH IYDLIRTRNI RVITIMSIIL WLTISVGYFG 
LSLDTPNLHG DIYVNCFLLA AVEVPAYVLA WLLLQYLPRR YSISAALFLG GSVLLFMQLV 
PSELFYLSTA LVMVGKFGIT SAYSMVYVYT AELYPTVVRN MGVGVSSTAS RLGSILSPYF 
VYLGAYDRFL PYILMGSLTI LTAILTLFFP ESFGVPLPDT IDQMLRVKGI KQWQIQSQTR 
MQKDGEESPT VLKSTAF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.