Genular: Defining Cellular Identity and Function

Details for: Slc7a7

Gene ID: 20540

Symbol: Slc7a7

Ensembl ID: ENSMUSG00000000958

Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

Associated with

Amino acid transport across the plasma membrane
(R-MMU-352230)
Basigin interactions
(R-MMU-210991)
Cell surface interactions at the vascular wall
(R-MMU-202733)
Hemostasis
(R-MMU-109582)
Slc-mediated transmembrane transport
(R-MMU-425407)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-MMU-425393)
Transport of small molecules
(R-MMU-382551)
Amino acid transmembrane transport
(GO:0003333)
Amino acid transport
(GO:0006865)
Basic amino acid transmembrane transport
(GO:1990822)
Basic amino acid transmembrane transporter activity
(GO:0015174)
Basolateral plasma membrane
(GO:0016323)
L-amino acid transmembrane transporter activity
(GO:0015179)
L-arginine transmembrane transport
(GO:1903826)
Leucine transport
(GO:0015820)
Membrane
(GO:0016020)
Plasma membrane
(GO:0005886)
Regulation of arginine metabolic process
(GO:0000821)
Transmembrane transport
(GO:0055085)
Transmembrane transporter activity
(GO:0022857)

Other Information

Proteins

Solute carrier family 7 member 7

Genular Protein ID: 2848252900

Symbol: YLAT1_MOUSE

Name: Solute carrier family 7 member 7

UniProtKB Accession Codes:

Q9Z1K8 Q9QWS1

Database IDs:

Citations:

PubMed ID: 9878049

Title: Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family.

PubMed ID: 9878049

DOI: 10.1093/emboj/18.1.49

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17376816

Title: Slc7a7 disruption causes fetal growth retardation by downregulating Igf1 in the mouse model of lysinuric protein intolerance.

PubMed ID: 17376816

DOI: 10.1152/ajpcell.00583.2006

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 31653080

Title: Inducible Slc7a7 Knockout Mouse Model Recapitulates Lysinuric Protein Intolerance Disease.

PubMed ID: 31653080

DOI: 10.3390/ijms20215294

Sequence Information:

Length: 510
Mass: 55677
Checksum: 9F30FB1B88126F6C
Sequence:

MVNSTKYEVA AQHEADDGSA LGDGASPVAE QVKLKKEISL LNGVCLIVGN MIGSGIFVSP 
KGVLMYSASF GLSLVIWAVG GIFSVFGALC YAELGTTIKK SGASYAYILE AFGGFLAFIR 
LWTSLLIIEP TSQAVIAITF ANYMVQPLFP SCGAPYAAGR LLAAACICLL TFINCAYVKW 
GTLVQDIFTY AKVLALIAVI IAGIVRLGQG ATANFENSFE GSSFAMGDIA LALYSALFSY 
SGWDTLNYVT EEIRNPERNL PLSIGISMPI VTIIYLLTNV AYYSVLDIKE ILASDAVAVT 
FADQIFGVFN WIIPVAVAFS CFGGLNASIV AASRLLFVGS REGHLPDAIC MVHVERFTPV 
PSLLFNGVLS LVYLCVEDIF QLINYYSFSY WFFVGLSIVG QLYLRWKDPD RPRPLKLSLF 
FPIIFCLCTI FLVAVPLYSD TINSLIGIGI ALSGLPFYFF IIRVPEHKRP LFLRRIVASI 
TRYLQILCMS VAAEMDLEDG ELSKQDPKSK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Slc7a7

Associated with

Other Information

Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family. PubMed ID: 9878049

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Slc7a7 disruption causes fetal growth retardation by downregulating Igf1 in the mouse model of lysinuric protein intolerance. PubMed ID: 17376816

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Inducible Slc7a7 Knockout Mouse Model Recapitulates Lysinuric Protein Intolerance Disease. PubMed ID: 31653080