Details for: Slpi

Gene ID: 20568

Symbol: Slpi

Ensembl ID: ENSMUSG00000017002

Description: secretory leukocyte peptidase inhibitor

Associated with

Other Information

Genular Protein ID: 846367337

Symbol: SLPI_MOUSE

Name: Antileukoproteinase

UniProtKB Accession Codes:

P97430 O09081 O09082

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 2 KEGG 1 MEROPS 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 9039268

Title: Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide.

PubMed ID: 9039268

DOI: 10.1016/s0092-8674(00)81880-2

PubMed ID: 9126337

Title: The cloning and characterization of a murine secretory leukocyte protease inhibitor cDNA.

PubMed ID: 9126337

DOI: 10.1006/bbrc.1997.6358

PubMed ID: 9351627

Title: Bacterial pneumonia causes augmented expression of the secretory leukoprotease inhibitor gene in the murine lung.

PubMed ID: 9351627

DOI: 10.1164/ajrccm.156.4.9701075

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11017147

Title: Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing.

PubMed ID: 11017147

DOI: 10.1038/80489

PubMed ID: 12526812

Title: Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair.

PubMed ID: 12526812

DOI: 10.1016/s0092-8674(02)01141-8

PubMed ID: 12615907

Title: Increased susceptibility to LPS-induced endotoxin shock in secretory leukoprotease inhibitor (SLPI)-deficient mice.

PubMed ID: 12615907

DOI: 10.1084/jem.20021824

PubMed ID: 18322212

Title: Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor.

PubMed ID: 18322212

DOI: 10.4049/jimmunol.180.6.4032

PubMed ID: 25030421

Title: Aberrant host defense against Leishmania major in the absence of SLPI.

PubMed ID: 25030421

DOI: 10.1189/jlb.4a0612-295rr

Sequence Information:

  • Length: 131
  • Mass: 14308
  • Checksum: A57C9E30FE711B8F
  • Sequence:
    • MKSCGLLPFT VLLALGILAP WTVEGGKNDA IKIGACPAKK PAQCLKLEKP QCRTDWECPG 
KQRCCQDACG SKCVNPVPIR KPVWRKPGRC VKTQARCMML NPPNVCQRDG QCDGKYKCCE 
GICGKVCLPP M

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.