Genular: Defining Cellular Identity and Function

Details for: Sst

Gene ID: 20604

Symbol: Sst

Ensembl ID: ENSMUSG00000004366

Description: somatostatin

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Gaba-ergic synapse
(GO:0098982)
Hormone activity
(GO:0005179)
Identical protein binding
(GO:0042802)
Neuronal cell body
(GO:0043025)
Neuronal dense core vesicle
(GO:0098992)
Receptor ligand activity
(GO:0048018)
Regulation of cell migration
(GO:0030334)
Regulation of postsynaptic membrane neurotransmitter receptor levels
(GO:0099072)
Somatostatin signaling pathway
(GO:0038170)

Other Information

Proteins

Somatostatin

Genular Protein ID: 716379149

Symbol: SMS_MOUSE

Name: Somatostatin

UniProtKB Accession Codes:

P60041 P01167

Database IDs:

Citations:

PubMed ID: 1969620

Title: Nucleotide sequence of the mouse preprosomatostatin gene.

PubMed ID: 1969620

DOI: 10.1093/nar/18.5.1287

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18753129

Title: Neuronostatin encoded by the somatostatin gene regulates neuronal, cardiovascular, and metabolic functions.

PubMed ID: 18753129

DOI: 10.1074/jbc.m804784200

PubMed ID: 24735892

Title: Neuronostatin inhibits glucose-stimulated insulin secretion via direct action on the pancreatic alpha-cell.

PubMed ID: 24735892

DOI: 10.1152/ajpendo.00599.2013

PubMed ID: 25012062

Title: Neuronostatin attenuates myocardial contractile function through inhibition of sarcoplasmic reticulum Ca2+-ATPase in murine heart.

PubMed ID: 25012062

DOI: 10.1159/000362969

PubMed ID: 26561648

Title: Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic alpha-cells.

PubMed ID: 26561648

DOI: 10.1152/ajpregu.00369.2014

Sequence Information:

Length: 116
Mass: 12746
Checksum: D48B5454C4490375
Sequence:

MLSCRLQCAL AALCIVLALG GVTGAPSDPR LRQFLQKSLA AATGKQELAK YFLAELLSEP 
NQTENDALEP EDLPQAAEQD EMRLELQRSA NSNPAMAPRE RKAGCKNFFW KTFTSC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sst

Associated with

Other Information

Nucleotide sequence of the mouse preprosomatostatin gene. PubMed ID: 1969620

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Neuronostatin encoded by the somatostatin gene regulates neuronal, cardiovascular, and metabolic functions. PubMed ID: 18753129

Neuronostatin inhibits glucose-stimulated insulin secretion via direct action on the pancreatic alpha-cell. PubMed ID: 24735892

Neuronostatin attenuates myocardial contractile function through inhibition of sarcoplasmic reticulum Ca2+-ATPase in murine heart. PubMed ID: 25012062