Genular: Defining Cellular Identity and Function

Details for: Sod1

Gene ID: 20655

Symbol: Sod1

Ensembl ID: ENSMUSG00000022982

Description: superoxide dismutase 1, soluble

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Detoxification of reactive oxygen species
(R-MMU-3299685)
Hemostasis
(R-MMU-109582)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Platelet degranulation
(R-MMU-114608)
Response to elevated platelet cytosolic ca2+
(R-MMU-76005)
Action potential initiation
(GO:0099610)
Anterograde axonal transport
(GO:0008089)
Antioxidant activity
(GO:0016209)
Apoptotic process
(GO:0006915)
Auditory receptor cell stereocilium organization
(GO:0060088)
Copper ion binding
(GO:0005507)
Cytoplasm
(GO:0005737)
Determination of adult lifespan
(GO:0008340)
Ectopic germ cell programmed cell death
(GO:0035234)
Embryo implantation
(GO:0007566)
Enzyme binding
(GO:0019899)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Gene expression
(GO:0010467)
Glutathione metabolic process
(GO:0006749)
Heart contraction
(GO:0060047)
Hydrogen peroxide biosynthetic process
(GO:0050665)
Identical protein binding
(GO:0042802)
Intracellular iron ion homeostasis
(GO:0006879)
Locomotory behavior
(GO:0007626)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Muscle cell cellular homeostasis
(GO:0046716)
Myeloid cell homeostasis
(GO:0002262)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of cholesterol biosynthetic process
(GO:0045541)
Negative regulation of developmental process
(GO:0051093)
Negative regulation of inflammatory response
(GO:0050728)
Negative regulation of neuron apoptotic process
(GO:0043524)
Negative regulation of reproductive process
(GO:2000242)
Neurofilament cytoskeleton organization
(GO:0060052)
Neuronal action potential
(GO:0019228)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Ovarian follicle development
(GO:0001541)
Oxidoreductase activity
(GO:0016491)
Peripheral nervous system myelin maintenance
(GO:0032287)
Positive regulation of catalytic activity
(GO:0043085)
Positive regulation of cytokine production
(GO:0001819)
Positive regulation of mapk cascade
(GO:0043410)
Positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
(GO:1902177)
Positive regulation of phagocytosis
(GO:0050766)
Positive regulation of superoxide anion generation
(GO:0032930)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein phosphatase 2b binding
(GO:0030346)
Reactive oxygen species metabolic process
(GO:0072593)
Regulation of blood pressure
(GO:0008217)
Regulation of gtpase activity
(GO:0043087)
Regulation of mitochondrial membrane potential
(GO:0051881)
Regulation of multicellular organism growth
(GO:0040014)
Regulation of protein kinase activity
(GO:0045859)
Relaxation of vascular associated smooth muscle
(GO:0060087)
Removal of superoxide radicals
(GO:0019430)
Response to axon injury
(GO:0048678)
Response to copper ion
(GO:0046688)
Response to ethanol
(GO:0045471)
Response to heat
(GO:0009408)
Response to hydrogen peroxide
(GO:0042542)
Response to nutrient levels
(GO:0031667)
Response to organic substance
(GO:0010033)
Response to oxidative stress
(GO:0006979)
Response to reactive oxygen species
(GO:0000302)
Response to superoxide
(GO:0000303)
Response to xenobiotic stimulus
(GO:0009410)
Retina homeostasis
(GO:0001895)
Retrograde axonal transport
(GO:0008090)
Sensory perception of sound
(GO:0007605)
Small gtpase binding
(GO:0031267)
Spermatogenesis
(GO:0007283)
Superoxide anion generation
(GO:0042554)
Superoxide dismutase activity
(GO:0004784)
Superoxide metabolic process
(GO:0006801)
Transmission of nerve impulse
(GO:0019226)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

SODC_MOUSE

Genular Protein ID: 766035797

Symbol: SODC_MOUSE

Name: N/A

UniProtKB Accession Codes:

P08228

Database IDs:

Citations:

PubMed ID: 3362683

Title: cDNA and deduced amino acid sequence of murine Cu-Zn superoxide dismutase.

PubMed ID: 3362683

DOI: 10.1093/nar/16.6.2728

PubMed ID: 2022332

Title: Isolation and analysis of the mouse genomic sequence encoding Cu(2+)-Zn2+ superoxide dismutase.

PubMed ID: 2022332

DOI: 10.1016/0378-1119(91)90126-v

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2391363

Title: Purification of an inhibitor of erythroid progenitor cell cycling and antagonist to interleukin 3 from mouse marrow cell supernatants and its identification as cytosolic superoxide dismutase.

PubMed ID: 2391363

DOI: 10.1083/jcb.111.3.1217

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21420488

Title: Knockout of SOD1 promotes conversion of selenocysteine to dehydroalanine in murine hepatic GPX1 protein.

PubMed ID: 21420488

DOI: 10.1016/j.freeradbiomed.2011.03.018

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 20727846

Title: Structures of mouse SOD1 and human/mouse SOD1 chimeras.

PubMed ID: 20727846

DOI: 10.1016/j.abb.2010.08.014

Sequence Information:

Length: 154
Mass: 15943
Checksum: CAE548C66043BAC4
Sequence:

MAMKAVCVLK GDGPVQGTIH FEQKASGEPV VLSGQITGLT EGQHGFHVHQ YGDNTQGCTS 
AGPHFNPHSK KHGGPADEER HVGDLGNVTA GKDGVANVSI EDRVISLSGE HSIIGRTMVV 
HEKQDDLGKG GNEESTKTGN AGSRLACGVI GIAQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sod1

Associated with

Other Information

cDNA and deduced amino acid sequence of murine Cu-Zn superoxide dismutase. PubMed ID: 3362683

Isolation and analysis of the mouse genomic sequence encoding Cu(2+)-Zn2+ superoxide dismutase. PubMed ID: 2022332

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Purification of an inhibitor of erythroid progenitor cell cycling and antagonist to interleukin 3 from mouse marrow cell supernatants and its identification as cytosolic superoxide dismutase. PubMed ID: 2391363

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Knockout of SOD1 promotes conversion of selenocysteine to dehydroalanine in murine hepatic GPX1 protein. PubMed ID: 21420488

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753

Structures of mouse SOD1 and human/mouse SOD1 chimeras. PubMed ID: 20727846